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Items: 1 to 20 of 147

1.
Stearoyl-CoA desaturase 1 inhibition induces ER stress-mediated apoptosis in ovarian cancer cells
Juwon Lee, Suin Jang, Jihye Im, Youngjin Han, Soochi Kim, HyunA Jo, Wenyu Wang, Untack Cho, Se Ik Kim, Aeran Seol, Boyun Kim, Yong Sang Song
J Ovarian Res. 2024; 17: 73. Published online 2024 Apr 2. doi: 10.1186/s13048-024-01389-1
PMCID:
PMC10988872
AbstractArticlePDF–5.6M
2.
Sulfotransferase SULT2B1 facilitates colon cancer metastasis by promoting SCD1‐mediated lipid metabolism
Gang Che, Wankun Wang, Jiawei Wang, Cheng He, Jie Yin, Zhendong Chen, Chao He, Xujing Wang, Yan Yang, Jian Liu
Clin Transl Med. 2024 Feb; 14(2): e1587. Published online 2024 Feb 19. doi: 10.1002/ctm2.1587
PMCID:
PMC10875708
AbstractArticlePDF–16M
3.
IGF2BP3 enhances lipid metabolism in cervical cancer by upregulating the expression of SCD
Chenying Han, Chenchen Hu, Tianyue Liu, Yuanjie Sun, Feiming Hu, Yuanli He, Jiaxing Zhang, Jiaxi Chen, Jiaqi Ding, Jiangjiang Fan, Xiyang Zhang, Jing Wang, Xupeng Qiao, Dongbo Jiang, Kun Yang, Shuya Yang
Cell Death Dis. 2024 Feb; 15(2): 138. Published online 2024 Feb 14. doi: 10.1038/s41419-024-06520-0
PMCID:
PMC10867090
AbstractArticlePDF–4.9M
4.
Allele-specific effect of various dietary fatty acids and ETS1 transcription factor on SCD1 expression
Kinga Tibori, Veronika Zámbó, Gabriella Orosz, Péter Szelényi, Farkas Sarnyai, Viola Tamási, Zsolt Rónai, Miklós Csala, Éva Kereszturi
Sci Rep. 2024; 14: 177. Published online 2024 Jan 2. doi: 10.1038/s41598-023-50700-5
PMCID:
PMC10761808
AbstractArticlePDF–1.6M
5.
Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis
Robert S. Kiss, Jarred Chicoine, Youssef Khalil, Robert Sladek, He Chen, Alessandro Pisaturo, Cyril Martin, Jessica D. Dale, Tegan A. Brudenell, Archith Kamath, Jeffrey Kyei-Boahen, Anouar Hafiane, Girija Daliah, Célia Alecki, Tayah S. Hopes, Martin Heier, Irene A. Aligianis, Jean-Jacques Lebrun, Julie Aspden, Emanuele Paci, Anja Kerksiek, Dieter Lütjohann, Peter Clayton, Jimi C. Wills, Alex von Kriegsheim, Tommy Nilsson, Eamonn Sheridan, Mark T. Handley
J Biol Chem. 2023 Nov; 299(11): 105295. Published online 2023 Sep 28. doi: 10.1016/j.jbc.2023.105295
PMCID:
PMC10641524
AbstractArticlePDF–3.8M
6.
The midnolin-proteasome pathway catches proteins for ubiquitination-independent degradation
Xin Gu, Christopher Nardone, Nolan Kamitaki, Aoyue Mao, Stephen J. Elledge, Michael E. Greenberg
Science. Author manuscript; available in PMC 2023 Oct 31.
Published in final edited form as: Science. 2023 Aug 25; 381(6660): eadh5021. Published online 2023 Aug 25. doi: 10.1126/science.adh5021
PMCID:
PMC10617673
AbstractArticlePDF–3.6M
7.
TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing
Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan
Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233
PMCID:
PMC10237422
AbstractArticlePDF–23M
8.
ADAR1-mediated RNA editing of SCD1 drives drug resistance and self-renewal in gastric cancer
Tin-Lok Wong, Jia-Jian Loh, Shixun Lu, Helen H. N. Yan, Hoi Cheong Siu, Ren Xi, Dessy Chan, Max J. F. Kam, Lei Zhou, Man Tong, John A. Copland, Leilei Chen, Jing-Ping Yun, Suet Yi Leung, Stephanie Ma
Nat Commun. 2023; 14: 2861. Published online 2023 May 19. doi: 10.1038/s41467-023-38581-8
PMCID:
PMC10199093
AbstractArticlePDF–6.6M
9.
PROX1 restrains ferroptosis via SCD transcription activation in colorectal cancer: PROX1 inhibits ferroptosis in CRC
Ruoxin Zhang, Dakui Luo, Zezhi Shan, Yufei Yang, Yi Qin, Qingguo Li, Xinxiang Li
Acta Biochim Biophys Sin (Shanghai) 2023 Apr; 55(4): 691–694. Published online 2023 Feb 23. doi: 10.3724/abbs.2023027
PMCID:
PMC10195136
ArticlePDF–824K
10.
Stearoyl-CoA Desaturases1 Accelerates Non-Small Cell Lung Cancer Metastasis by Promoting Aromatase Expression to Improve Estrogen Synthesis
Jiaping Chen, Yangwei Wang, Wangyang Meng, Rong Zhao, Wei Lin, Han Xiao, Yongde Liao
Int J Mol Sci. 2023 Apr; 24(7): 6826. Published online 2023 Apr 6. doi: 10.3390/ijms24076826
PMCID:
PMC10095487
AbstractArticlePDF–15M
11.
Assessment of community efforts to advance network-based prediction of protein–protein interactions
Xu-Wen Wang, Lorenzo Madeddu, Kerstin Spirohn, Leonardo Martini, Adriano Fazzone, Luca Becchetti, Thomas P. Wytock, István A. Kovács, Olivér M. Balogh, Bettina Benczik, Mátyás Pétervári, Bence Ágg, Péter Ferdinandy, Loan Vulliard, Jörg Menche, Stefania Colonnese, Manuela Petti, Gaetano Scarano, Francesca Cuomo, Tong Hao, Florent Laval, Luc Willems, Jean-Claude Twizere, Marc Vidal, Michael A. Calderwood, Enrico Petrillo, Albert-László Barabási, Edwin K. Silverman, Joseph Loscalzo, Paola Velardi, Yang-Yu Liu
Nat Commun. 2023; 14: 1582. Published online 2023 Mar 22. doi: 10.1038/s41467-023-37079-7
PMCID:
PMC10033937
AbstractArticlePDF–1.5M
12.
RUNX2 interacts with SCD1 and activates Wnt/β‐catenin signaling pathway to promote the progression of clear cell renal cell carcinoma
Xiandong Song, Junlong Liu, Bitian Liu, Chiyuan Piao, Chuize Kong, Zhenhua Li
Cancer Med. 2023 Mar; 12(5): 5764–5780. Published online 2022 Oct 6. doi: 10.1002/cam4.5326
PMCID:
PMC10028032
AbstractArticlePDF–18M
13.
SNORD88C guided 2′-O-methylation of 28S rRNA regulates SCD1 translation to inhibit autophagy and promote growth and metastasis in non-small cell lung cancer
Kangyu Wang, Shiwen Wang, Yue Zhang, Li Xie, Xingguo Song, Xianrang Song
Cell Death Differ. 2023 Feb; 30(2): 341–355. Published online 2022 Nov 14. doi: 10.1038/s41418-022-01087-9
PMCID:
PMC9950066
AbstractArticlePDF–6.1M
14.
Stearoyl CoA Desaturase-1 Silencing in Glioblastoma Cells: Phospholipid Remodeling and Cytotoxicity Enhanced upon Autophagy Inhibition
Catarina M. Morais, Ana M. Cardoso, Ana Rita D. Araújo, Ana Reis, Pedro Domingues, Maria Rosário M. Domingues, Maria C. Pedroso de Lima, Amália S. Jurado
Int J Mol Sci. 2022 Nov; 23(21): 13014. Published online 2022 Oct 27. doi: 10.3390/ijms232113014
PMCID:
PMC9654881
AbstractArticlePDF–3.3M
15.
SARS-CoV-2 Nsp6 damages Drosophila heart and mouse cardiomyocytes through MGA/MAX complex-mediated increased glycolysis
Jun-yi Zhu, Guanglei Wang, Xiaohu Huang, Hangnoh Lee, Jin-Gu Lee, Penghua Yang, Joyce van de Leemput, Weiliang Huang, Maureen A. Kane, Peixin Yang, Zhe Han
Commun Biol. 2022; 5: 1039. Published online 2022 Sep 30. doi: 10.1038/s42003-022-03986-6
PMCID:
PMC9523645
AbstractArticlePDF–3.9M
16.
SMYD3 Impedes Small Cell Lung Cancer Sensitivity to Alkylation Damage through RNF113A Methylation–Phosphorylation Cross-talk
Valentina Lukinović, Simone Hausmann, Gael S. Roth, Clement Oyeniran, Tanveer Ahmad, Ning Tsao, Joshua R. Brickner, Alexandre G. Casanova, Florent Chuffart, Ana Morales Benitez, Jessica Vayr, Rebecca Rodell, Marianne Tardif, Pascal W.T.C. Jansen, Yohann Couté, Michiel Vermeulen, Pierre Hainaut, Pawel K. Mazur, Nima Mosammaparast, Nicolas Reynoird
Cancer Discov. 2022 Sep 2; 12(9): 2158–2179. Published online 2022 Jul 12. doi: 10.1158/2159-8290.CD-21-0205
PMCID:
PMC9437563
AbstractArticlePDF–9.5M
17.
Selenocysteine Machinery Primarily Supports TXNRD1 and GPX4 Functions and Together They Are Functionally Linked with SCD and PRDX6
Didac Santesmasses, Vadim N. Gladyshev
Biomolecules. 2022 Aug; 12(8): 1049. Published online 2022 Jul 28. doi: 10.3390/biom12081049
PMCID:
PMC9405853
AbstractArticlePDF–2.0M
18.
Targeted inhibition of ubiquitin signaling reverses metabolic reprogramming and suppresses glioblastoma growth
Rossella Delle Donne, Rosa Iannucci, Laura Rinaldi, Luca Roberto, Maria A. Oliva, Emanuela Senatore, Domenica Borzacchiello, Luca Lignitto, Giorgio Giurato, Francesca Rizzo, Assunta Sellitto, Francesco Chiuso, Salvatore Castaldo, Giovanni Scala, Virginia Campani, Valeria Nele, Giuseppe De Rosa, Chiara D’Ambrosio, Corrado Garbi, Andrea Scaloni, Alessandro Weisz, Concetta Ambrosino, Antonella Arcella, Antonio Feliciello
Commun Biol. 2022; 5: 780. Published online 2022 Aug 2. doi: 10.1038/s42003-022-03639-8
PMCID:
PMC9345969
AbstractArticlePDF–2.3M
19.
HSF1 phosphorylation establishes an active chromatin state via the TRRAP–TIP60 complex and promotes tumorigenesis
Mitsuaki Fujimoto, Ryosuke Takii, Masaki Matsumoto, Mariko Okada, Keiich I. Nakayama, Ryuichiro Nakato, Katsunori Fujiki, Katsuhiko Shirahige, Akira Nakai
Nat Commun. 2022; 13: 4355. Published online 2022 Jul 29. doi: 10.1038/s41467-022-32034-4
PMCID:
PMC9338313
AbstractArticlePDF–2.8M
20.
Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery
Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili
Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z
PMCID:
PMC9279285
AbstractArticlePDF–2.5M

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