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Select item 105454371.

DOT1L deletion impairs the development of cortical parvalbumin-expressing interneurons

Arquimedes Cheffer, Marta Garcia-Miralles, Esther Maier, Ipek Akol, Henriette Franz, Vandana Shree Vedartham Srinivasan, Tanja Vogel

Cereb Cortex. 2023 Oct 1; 33(19): 10272–10285. Published online 2023 Aug 11. doi: 10.1093/cercor/bhad281

PMCID:: PMC10545437

Abstract Article PDF–2.8M

Select item 105308922.

Conditional Deletion of Foxg1 Delayed Myelination during Early Postnatal Brain Development

Guangliang Cao, Congli Sun, Hualin Shen, Dewei Qu, Chuanlu Shen, Haiqin Lu

Int J Mol Sci. 2023 Sep; 24(18): 13921. Published online 2023 Sep 10. doi: 10.3390/ijms241813921

PMCID:: PMC10530892

Abstract Article PDF–4.2M

Select item 105220213.

Notch pathway mutants do not equivalently perturb mouse embryonic retinal development

Bernadett Bosze, Julissa Suarez-Navarro, Illiana Cajias, Joseph A. Brzezinski IV, Nadean L. Brown

PLoS Genet. 2023 Sep; 19(9): e1010928. Published online 2023 Sep 26. doi: 10.1371/journal.pgen.1010928

PMCID:: PMC10522021

Abstract Article PDF–5.9M

Select item 105064004.

Inactivation of Fgf3 and Fgf4 within the Fgf3/Fgf4/Fgf15 gene cluster reveals their redundant requirement for mouse inner ear induction and embryonic survival

Laura Zelarayan, Victor Vendrell, Elena Domínguez-Frutos, Iris López-Hernández, Kiril Schimmang-Alonso, María Teresa Alonso, Yolanda Alvarez, Hannes Maier, Matthew J. Anderson, Mark Lewandoski, Thomas Schimmang

Dev Dyn. Author manuscript; available in PMC 2023 Sep 18.

Published in final edited form as: Dev Dyn. 2022 May; 251(5): 877–884. Published online 2021 Nov 12. doi: 10.1002/dvdy.435

PMCID:: PMC10506400

Abstract Article PDF–1.3M

Select item 104098005.

SNIP1 and PRC2 coordinate cell fates of neural progenitors during brain development

Yurika Matsui, Mohamed Nadhir Djekidel, Katherine Lindsay, Parimal Samir, Nina Connolly, Gang Wu, Xiaoyang Yang, Yiping Fan, Beisi Xu, Jamy C. Peng

Nat Commun. 2023; 14: 4754. Published online 2023 Aug 8. doi: 10.1038/s41467-023-40487-4

PMCID:: PMC10409800

Abstract Article PDF–5.3M

Select item 103904926.

Three-dimensional molecular architecture of mouse organogenesis

Fangfang Qu, Wenjia Li, Jian Xu, Ruifang Zhang, Jincan Ke, Xiaodie Ren, Xiaogao Meng, Lexin Qin, Jingna Zhang, Fangru Lu, Xin Zhou, Xi Luo, Zhen Zhang, Minhan Wang, Guangming Wu, Duanqing Pei, Jiekai Chen, Guizhong Cui, Shengbao Suo, Guangdun Peng

Nat Commun. 2023; 14: 4599. Published online 2023 Jul 31. doi: 10.1038/s41467-023-40155-7

PMCID:: PMC10390492

Abstract Article PDF–13M

Select item 103095807.

Notch directs telencephalic development and controls neocortical neuron fate determination by regulating microRNA levels

Jisoo S. Han, Elizabeth Fishman-Williams, Steven C. Decker, Keiko Hino, Raenier V. Reyes, Nadean L. Brown, Sergi Simó, Anna La Torre

Development. 2023 Jun 1; 150(11): dev201408. Published online 2023 Jun 5. doi: 10.1242/dev.201408

PMCID:: PMC10309580

Abstract Article

Select item 102682408.

ZBTB20 is essential for cochlear maturation and hearing in mice

Zhifang Xie, Xian-Hua Ma, Qiu-Fang Bai, Jie Tang, Jian-He Sun, Fei Jiang, Wei Guo, Chen-Ma Wang, Rui Yang, Yin-Chuan Wen, Fang-Yuan Wang, Yu-Xia Chen, Hai Zhang, David Z. He, Matthew W. Kelley, Shiming Yang, Weiping J. Zhang

Proc Natl Acad Sci U S A. 2023 Jun 13; 120(24): e2220867120. Published online 2023 Jun 6. doi: 10.1073/pnas.2220867120

PMCID:: PMC10268240

Abstract Article PDF–7.7M

Select item 102473809.

Myelin dysfunction drives amyloid-β deposition in models of Alzheimer’s disease

Constanze Depp, Ting Sun, Andrew Octavian Sasmita, Lena Spieth, Stefan A. Berghoff, Taisiia Nazarenko, Katharina Overhoff, Agnes A. Steixner-Kumar, Swati Subramanian, Sahab Arinrad, Torben Ruhwedel, Wiebke Möbius, Sandra Göbbels, Gesine Saher, Hauke B. Werner, Alkmini Damkou, Silvia Zampar, Oliver Wirths, Maik Thalmann, Mikael Simons, Takashi Saito, Takaomi Saido, Dilja Krueger-Burg, Riki Kawaguchi, Michael Willem, Christian Haass, Daniel Geschwind, Hannelore Ehrenreich, Ruth Stassart, Klaus-Armin Nave

Nature. 2023; 618(7964): 349–357. Published online 2023 May 31. doi: 10.1038/s41586-023-06120-6

PMCID:: PMC10247380

Abstract Article PDF–19M

Select item 1018337010.

POLR1A variants underlie phenotypic heterogeneity in craniofacial, neural, and cardiac anomalies

Kelly Smallwood, Kristin E.N. Watt, Satoru Ide, Kristina Baltrunaite, Chad Brunswick, Katherine Inskeep, Corrine Capannari, Margaret P. Adam, Amber Begtrup, Debora R. Bertola, Laurie Demmer, Erin Demo, Orrin Devinsky, Emily R. Gallagher, Maria J. Guillen Sacoto, Robert Jech, Boris Keren, Jennifer Kussmann, Roger Ladda, Lisa A. Lansdon, Sebastian Lunke, Anne Mardy, Kirsty McWalters, Richard Person, Laura Raiti, Noriko Saitoh, Carol J. Saunders, Rhonda Schnur, Matej Skorvanek, Susan L. Sell, Anne Slavotinek, Bonnie R. Sullivan, Zornitza Stark, Joseph D. Symonds, Tara Wenger, Sacha Weber, Sandra Whalen, Susan M. White, Juliane Winkelmann, Michael Zech, Shimriet Zeidler, Kazuhiro Maeshima, Rolf W. Stottmann, Paul A. Trainor, K. Nicole Weaver

Am J Hum Genet. 2023 May 4; 110(5): 809–825. Published online 2023 Apr 18. doi: 10.1016/j.ajhg.2023.03.014

PMCID:: PMC10183370

Abstract Article PDF–4.3M

Select item 993437611.

Cell-autonomous requirement for ACE2 across organs in lethal mouse SARS-CoV-2 infection

Alan T. Tang, David W. Buchholz, Katherine M. Szigety, Brian Imbiakha, Siqi Gao, Maxwell Frankfurter, Min Wang, Jisheng Yang, Peter Hewins, Patricia Mericko-Ishizuka, N Adrian Leu, Stephanie Sterling, Isaac A. Monreal, Julie Sahler, Avery August, Xuming Zhu, Kellie A. Jurado, Mingang Xu, Edward E. Morrisey, Sarah E. Millar, Hector C. Aguilar, Mark L. Kahn

PLoS Biol. 2023 Feb; 21(2): e3001989. Published online 2023 Feb 6. doi: 10.1371/journal.pbio.3001989

PMCID:: PMC9934376

Abstract Article PDF–8.2M

Select item 993121712.

FOXG1 drives transcriptomic networks to specify principal neuron subtypes during the development of the medial pallium

Ru Ba, Lin Yang, Baoshen Zhang, Pengfei Jiang, Zhipeng Ding, Xue Zhou, Zhengang Yang, Chunjie Zhao

Sci Adv. 2023 Feb; 9(7): eade2441. Published online 2023 Feb 15. doi: 10.1126/sciadv.ade2441

PMCID:: PMC9931217

Abstract Article PDF–2.5M

Select item 990802113.

Cx26 heterozygous mutations cause hyperacusis-like hearing oversensitivity and increase susceptibility to noise

Li-Man Liu, Chun Liang, Jin Chen, Shu Fang, Hong-Bo Zhao

Sci Adv. 2023 Feb; 9(6): eadf4144. Published online 2023 Feb 8. doi: 10.1126/sciadv.adf4144

PMCID:: PMC9908021

Abstract Article PDF–1.6M

Select item 984574514.

Overactive Wnt5a signaling disrupts hair follicle polarity during mouse skin development

Laura Simonson, Ethan Oldham, Hao Chang

Development. 2022 Nov 15; 149(22): dev200816. Published online 2022 Nov 16. doi: 10.1242/dev.200816

PMCID:: PMC9845745

Abstract Article

Select item 981279515.

Differential vulnerability of adult neurogenic niches to dosage of the neurodevelopmental-disorder linked gene Foxg1

Iris Schäffner, Marie-Theres Wittmann, Tanja Vogel, D. Chichung Lie

Mol Psychiatry. 2023; 28(1): 497–514. Published online 2022 Mar 22. doi: 10.1038/s41380-022-01497-8

PMCID:: PMC9812795

Abstract Article PDF–10M

Select item 973585416.

FOXG1 Contributes Adult Hippocampal Neurogenesis in Mice

Jia Wang, Hong-Ru Zhai, Si-Fei Ma, Hou-Zhen Shi, Wei-Jun Zhang, Qi Yun, Wen-Jun Liu, Zi-Zhong Liu, Wei-Ning Zhang

Int J Mol Sci. 2022 Dec; 23(23): 14979. Published online 2022 Nov 29. doi: 10.3390/ijms232314979

PMCID:: PMC9735854

Abstract Article PDF–7.3M

Select item 958362017.

OFCD Syndrome and Extraembryonic Defects are Revealed by Conditional Mutation of the Polycomb-group Repressive Complex 1.1 (PRC1.1) Gene Bcor

Michelle Y. Hamline, Connie M. Corcoran, Joseph A. Wamstad, Isabelle Miletich, Jifan Feng, Jamie L. Lohr, Myriam Hemberger, Paul T. Sharpe, Micah D. Gearhart, Vivian J. Bardwell

Dev Biol. Author manuscript; available in PMC 2022 Oct 20.

Published in final edited form as: Dev Biol. 2020 Dec 1; 468(1-2): 110–132. Published online 2020 Jul 18. doi: 10.1016/j.ydbio.2020.06.013

PMCID:: PMC9583620

Abstract Article PDF–4.9M

Select item 958147818.

RGS12 polarizes the GPSM2-GNAI complex to organize and elongate stereocilia in sensory hair cells

Anil Akturk, Matthew Day, Basile Tarchini

Sci Adv. 2022 Oct; 8(42): eabq2826. Published online 2022 Oct 19. doi: 10.1126/sciadv.abq2826

PMCID:: PMC9581478

Abstract Article PDF–4.3M

Select item 957397919.

BAF (mSWI/SNF) complex regulates mediolateral cortical patterning in the developing forebrain

Huong Nguyen, Godwin Sokpor, Arpan Parichha, Linh Pham, Nidhi Saikhedkar, Yuanbin Xie, Pauline Antonie Ulmke, Joachim Rosenbusch, Mehdi Pirouz, Rüdiger Behr, Anastassia Stoykova, Beate Brand-Saberi, Huu Phuc Nguyen, Jochen F. Staiger, Shubha Tole, Tran Tuoc

Front Cell Dev Biol. 2022; 10: 1011109. Published online 2022 Oct 3. doi: 10.3389/fcell.2022.1011109

PMCID:: PMC9573979

Abstract Article PDF–5.6M

Select item 955562720.

Behavioral and brain anatomical analysis of Foxg1 heterozygous mice

Kirsty R. Erickson, Rebekah Farmer, Jonathan K. Merritt, Zeljka Miletic Lanaghan, Mark D. Does, Karthik Ramadass, Bennett A. Landman, Laurie E. Cutting, Jeffrey L. Neul

PLoS One. 2022; 17(10): e0266861. Published online 2022 Oct 12. doi: 10.1371/journal.pone.0266861

PMCID:: PMC9555627

Abstract Article PDF–1.0M

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