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Select item 108168501.

Congenital Hyperinsulinism in Humans and Insulin Secretory Dysfunction in Mice Caused by Biallelic DNAJC3 Variants

Alena Welters, Oliver Nortmann, Laura Wörmeyer, Clemens Freiberg, Daniel Eberhard, Nadine Bachmann, Carsten Bergmann, Ertan Mayatepek, Thomas Meissner, Sebastian Kummer

Int J Mol Sci. 2024 Jan; 25(2): 1270. Published online 2024 Jan 20. doi: 10.3390/ijms25021270

PMCID:: PMC10816850

Abstract Article PDF–979K

Select item 102971872.

Neuronal p58^IPK Protects Retinal Ganglion Cells Independently of Macrophage/Microglia Activation in Ocular Hypertension

Todd McLaughlin, Jinli Wang, Liyun Jia, Fuguo Wu, Yaqin Wang, Joshua J. Wang, Xiuqian Mu, Sarah X. Zhang

Cells. 2023 Jun; 12(12): 1558. Published online 2023 Jun 6. doi: 10.3390/cells12121558

PMCID:: PMC10297187

Abstract Article PDF–4.9M

Select item 79387703.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 66927704.

Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics

Joel D. Federspiel, Todd M. Greco, Krystal K. Lum, Ileana M. Cristea

Mol Cell Proteomics. 2019 Aug 9; 18(8 Suppl 1): S92–S113. Published online 2019 Apr 30. doi: 10.1074/mcp.RA118.001253

PMCID:: PMC6692770

Abstract Article PDF–7.7M

Select item 62980405.

Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors

Hyeonwoo Kim, Christiane D. Wrann, Mark Jedrychowski, Sara Vidoni, Yukiko Kitase, Kenichi Nagano, Chenhe Zhou, Joshua Chou, Virginia-Jeni A. Parkman, Scott J. Novick, Timothy S. Strutzenberg, Bruce D. Pascal, Phuong T. Le, Daniel J. Brooks, Alexander M. Roche, Kaitlyn K. Gerber, Laura Mattheis, Wenjing Chen, Hua Tu, Mary L. Bouxsein, Patrick R. Griffin, Roland Baron, Clifford J. Rosen, Lynda F. Bonewald, Bruce M. Spiegelman

Cell. Author manuscript; available in PMC 2019 Dec 13.

Published in final edited form as: Cell. 2018 Dec 13; 175(7): 1756–1768.e17. doi: 10.1016/j.cell.2018.10.025

Correction in:: Cell. 2019 Jul 11; 178(2): 507–508.

PMCID:: PMC6298040

Abstract Article PDF–1.2M

Select item 61373206.

p58^IPK Is an Endogenous Neuroprotectant for Retinal Ganglion Cells

Todd McLaughlin, Narayan Dhimal, Junhua Li, Joshua Jianxin Wang, Sarah Xin Zhang

Front Aging Neurosci. 2018; 10: 267. Published online 2018 Sep 7. doi: 10.3389/fnagi.2018.00267

PMCID:: PMC6137320

Abstract Article PDF–1.6M

Select item 58258707.

The ATPase activity of Asna1/TRC40 is required for pancreatic progenitor cell survival

Stefan Norlin, Vishal Parekh, Helena Edlund

Development. 2018 Jan 1; 145(1): dev154468. doi: 10.1242/dev.154468

PMCID:: PMC5825870

Abstract Article

Select item 50689258.

Hepatocyte DACH1 is Increased in Obesity Via Nuclear Exclusion of HDAC4 and Promotes Hepatic Insulin Resistance

Lale Ozcan, Devram S. Ghorpade, Ze Zheng, Jane Cristina de Souza, Ke Chen, Marc Bessler, Melissa Bagloo, Beth Schrope, Richard Pestell, Ira Tabas

Cell Rep. Author manuscript; available in PMC 2016 Oct 18.

Published in final edited form as: Cell Rep. 2016 Jun 7; 15(10): 2214–2225. Published online 2016 May 26. doi: 10.1016/j.celrep.2016.05.006

Correction in:: Cell Rep. 2022 Jun 21; 39(12): 111015.

PMCID:: PMC5068925

Abstract Article PDF–1.7M

Select item 50503239.

Disruption of Protein Processing in the Endoplasmic Reticulum of DYT1 Knock-in Mice Implicates Novel Pathways in Dystonia Pathogenesis

Genevieve Beauvais, Nicole M. Bode, Jaime L. Watson, Hsiang Wen, Kevin A. Glenn, Hiroyuki Kawano, N. Charles Harata, Michelle E. Ehrlich, Pedro Gonzalez-Alegre

J Neurosci. 2016 Oct 5; 36(40): 10245–10256. doi: 10.1523/JNEUROSCI.0669-16.2016

PMCID:: PMC5050323

Abstract Article PDF–3.1M

Select item 494220810.

The 78-kD Glucose-Regulated Protein Regulates Endoplasmic Reticulum Homeostasis and Distal Epithelial Cell Survival during Lung Development

Per Flodby, Changgong Li, Yixin Liu, Hongjun Wang, Crystal N. Marconett, Ite A. Laird-Offringa, Parviz Minoo, Amy S. Lee, Beiyun Zhou

Am J Respir Cell Mol Biol. 2016 Jul; 55(1): 135–149. doi: 10.1165/rcmb.2015-0327OC

PMCID:: PMC4942208

Abstract Article PDF–3.7M

Select item 451221411.

Antioxidants Complement the Requirement for Protein Chaperone Function to Maintain β-Cell Function and Glucose Homeostasis

Jaeseok Han, Benbo Song, Jiun Kim, Vamsi K. Kodali, Anita Pottekat, Miao Wang, Justin Hassler, Shiyu Wang, Subramaniam Pennathur, Sung Hoon Back, Michael G. Katze, Randal J. Kaufman

Diabetes. 2015 Aug; 64(8): 2892–2904. Published online 2015 Mar 20. doi: 10.2337/db14-1357

PMCID:: PMC4512214

Abstract Article PDF–3.1M

Select item 434043212.

Identification of p58^IPK as a Novel Neuroprotective Factor for Retinal Neurons

Evgenii Boriushkin, Joshua J. Wang, Junhua Li, Guangjun Jing, Gail M. Seigel, Sarah X. Zhang

Invest Ophthalmol Vis Sci. 2015 Feb; 56(2): 1374–1386. Published online 2015 Feb 25. doi: 10.1167/iovs.14-15196

PMCID:: PMC4340432

Abstract Article PDF–2.4M

Select item 420114913.

Deletion of P58^IPK, the Cellular Inhibitor of the Protein Kinases PKR and PERK, Causes Bone Changes and Joint Degeneration in Mice

Sophie J. Gilbert, Lee B. Meakin, Cleo S. Bonnet, Mari A. Nowell, Warren C. Ladiges, John Morton, Victor C. Duance, Deborah J. Mason

Front Endocrinol (Lausanne) 2014; 5: 174. Published online 2014 Oct 17. doi: 10.3389/fendo.2014.00174

PMCID:: PMC4201149

Abstract Article PDF–4.2M

Select item 390105014.

Synthetic embryonic lethality upon deletion of the ER cochaperone p58^IPK and the ER stress sensor ATF6α

Javier A. Gomez, Heather M. Tyra, Diane DeZwaan McCabe, Alicia K. Olivier, D. Thomas Rutkowski

Biochem Biophys Res Commun. Author manuscript; available in PMC 2015 Jan 3.

Published in final edited form as: Biochem Biophys Res Commun. 2014 Jan 3; 443(1): 115–119. Published online 2013 Nov 22. doi: 10.1016/j.bbrc.2013.11.060

PMCID:: PMC3901050

Abstract Article PDF–1.6M

Select item 344473015.

D-2-hydroxyglutarate produced by mutant IDH1 perturbs collagen maturation and basement membrane function

Masato Sasaki, Christiane B. Knobbe, Momoe Itsumi, Andrew J. Elia, Isaac S. Harris, Iok In Christine Chio, Rob A. Cairns, Susan McCracken, Andrew Wakeham, Jillian Haight, Annick You Ten, Bryan Snow, Takeshi Ueda, Satoshi Inoue, Kazuo Yamamoto, Myunggon Ko, Anjana Rao, Katharine E. Yen, Shinsan M. Su, Tak Wah Mak

Genes Dev. 2012 Sep 15; 26(18): 2038–2049. doi: 10.1101/gad.198200.112

PMCID:: PMC3444730

Abstract Article PDF–1.6M

Select item 317805916.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 291899917.

Coxsackievirus B3 Infection Activates the Unfolded Protein Response and Induces Apoptosis through Downregulation of p58^IPK and Activation of CHOP and SREBP1

Huifang M. Zhang, Xin Ye, Yue Su, Ji Yuan, Zhen Liu, David A. Stein, Decheng Yang

J Virol. 2010 Sep; 84(17): 8446–8459. Published online 2010 Jun 16. doi: 10.1128/JVI.01416-09

PMCID:: PMC2918999

Abstract Article PDF–2.0M

Select item 285953218.

Deficiency of Suppressor Enhancer Lin12 1 Like (SEL1L) in Mice Leads to Systemic Endoplasmic Reticulum Stress and Embryonic Lethality

Adam B. Francisco, Rajni Singh, Shuai Li, Anish K. Vani, Liu Yang, Robert J. Munroe, Giuseppe Diaferia, Marina Cardano, Ida Biunno, Ling Qi, John C. Schimenti, Qiaoming Long

J Biol Chem. 2010 Apr 30; 285(18): 13694–13703. Published online 2010 Mar 2. doi: 10.1074/jbc.M109.085340

PMCID:: PMC2859532

Abstract Article PDF–2.5M

Select item 285199719.

Progressive renal injury from transgenic expression of human carbonic anhydrase IV folding mutants is enhanced by deficiency of p58^IPK

Rupak Datta, Gul N. Shah, Timothy S. Rubbelke, Abdul Waheed, Michael Rauchman, Alan G. Goodman, Michael G. Katze, William S. Sly

Proc Natl Acad Sci U S A. 2010 Apr 6; 107(14): 6448–6452. Published online 2010 Mar 22. doi: 10.1073/pnas.1001905107

PMCID:: PMC2851997

Abstract Article PDF–507K

Select item 284702920.

Crystal structure of P58(IPK) TPR fragment reveals the mechanism for its molecular chaperone activity in UPR

Jiahui Tao, Kseniya Petrova, David Ron, Bingdong Sha

J Mol Biol. Author manuscript; available in PMC 2011 Apr 16.

Published in final edited form as: J Mol Biol. 2010 Apr 16; 397(5): 1307–1315. Published online 2010 Feb 22. doi: 10.1016/j.jmb.2010.02.028

PMCID:: PMC2847029

Abstract Article PDF–3.0M

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