PMC Links for GEO Profiles (Select 75242395) - PMC

Links from GEO Profiles

Items: 1 to 20 of 150

<< First< Prev

Page of 8

Select item 107193131.

Enhanced SREBP2-driven cholesterol biosynthesis by PKCλ/ι deficiency in intestinal epithelial cells promotes aggressive serrated tumorigenesis

Yu Muta, Juan F. Linares, Anxo Martinez-Ordoñez, Angeles Duran, Tania Cid-Diaz, Hiroto Kinoshita, Xiao Zhang, Qixiu Han, Yuki Nakanishi, Naoko Nakanishi, Thekla Cordes, Gurpreet K. Arora, Marc Ruiz-Martinez, Miguel Reina-Campos, Hiroaki Kasashima, Masakazu Yashiro, Kiyoshi Maeda, Ana Albaladejo-Gonzalez, Daniel Torres-Moreno, José García-Solano, Pablo Conesa-Zamora, Giorgio Inghirami, Christian M. Metallo, Timothy F. Osborne, Maria T. Diaz-Meco, Jorge Moscat

Nat Commun. 2023; 14: 8075. Published online 2023 Dec 13. doi: 10.1038/s41467-023-43690-5

PMCID:: PMC10719313

Abstract Article PDF–7.4M

Select item 98450192.

Protein kinase C_ι and SRC signaling define reciprocally related subgroups of glioblastoma with distinct therapeutic vulnerabilities

Rajappa S. Kenchappa, Yi Liu, Michael G. Argenziano, Matei A. Banu, Ann C. Mladek, Rita West, Amanda Luu, Alfredo Quiñones-Hinojosa, Dolores Hambardzumyan, Verline Justilien, Michael Leitges, Jann N. Sarkaria, Peter A. Sims, Peter Canoll, Nicole R. Murray, Alan P. Fields, Steven S. Rosenfeld

Cell Rep. Author manuscript; available in PMC 2023 Jan 17.

Published in final edited form as: Cell Rep. 2021 Nov 23; 37(8): 110054. doi: 10.1016/j.celrep.2021.110054

PMCID:: PMC9845019

Abstract Article PDF–2.7M

Select item 98161113.

An entosis-like process induces mitotic disruption in Pals1 microcephaly pathogenesis

Noelle A. Sterling, Jun Young Park, Raehee Park, Seo-Hee Cho, Seonhee Kim

Nat Commun. 2023; 14: 82. Published online 2023 Jan 5. doi: 10.1038/s41467-022-35719-y

PMCID:: PMC9816111

Abstract Article PDF–7.8M

Select item 92121704.

Identification of Arhgef12 and Prkci as genetic modifiers of retinal dysplasia in the Crb1^rd8 mouse model

Sonia M. Weatherly, Gayle B. Collin, Jeremy R. Charette, Lisa Stone, Nattaya Damkham, Lillian F. Hyde, James G. Peterson, Wanda Hicks, Gregory W. Carter, Jürgen K. Naggert, Mark P. Krebs, Patsy M. Nishina

PLoS Genet. 2022 Jun; 18(6): e1009798. Published online 2022 Jun 8. doi: 10.1371/journal.pgen.1009798

PMCID:: PMC9212170

Abstract Article PDF–6.4M

Select item 91708185.

Maternal nicotine exposure induces congenital heart defects in the offspring of mice

Elizabeth R. Greco, Anish Engineer, Tana Saiyin, Xiangru Lu, MengQi Zhang, Douglas L. Jones, Qingping Feng

J Cell Mol Med. 2022 Jun; 26(11): 3223–3234. Published online 2022 May 6. doi: 10.1111/jcmm.17328

PMCID:: PMC9170818

Abstract Article PDF–4.0M

Select item 90669856.

Deficiency of PKCλ/ι alleviates the liver pathologic impairment of Schistosoma japonicum infection by thwarting Th2 response

Congjin Mei, Yingying Yang, Panpan Dong, Lijun Song, Yonghua Zhou, Yongliang Xu, Chuanxin Yu

Parasit Vectors. 2022; 15: 154. Published online 2022 May 3. doi: 10.1186/s13071-022-05283-x

PMCID:: PMC9066985

Abstract Article PDF–2.6M

Select item 85710547.

PKCλ/ι inhibition activates an ULK2-mediated interferon response to repress tumorigenesis

Juan F. Linares, Xiao Zhang, Anxo Martinez-Ordoñez, Angeles Duran, Hiroto Kinoshita, Hiroaki Kasashima, Naoko Nakanishi, Yuki Nakanishi, Ryan Carelli, Luca Cappelli, Esperanza Arias, Masakazu Yashiro, Masaichi Ohira, Sanjay Patel, Giorgio Inghirami, Massimo Loda, Ana Maria Cuervo, Maria T. Diaz-Meco, Jorge Moscat

Mol Cell. Author manuscript; available in PMC 2022 Nov 4.

Published in final edited form as: Mol Cell. 2021 Nov 4; 81(21): 4509–4526.e10. Published online 2021 Sep 23. doi: 10.1016/j.molcel.2021.08.039

PMCID:: PMC8571054

Abstract Article PDF–4.2M

Select item 81291418.

EMX2-GPR156-Gαi reverses hair cell orientation in mechanosensory epithelia

Katie S. Kindt, Anil Akturk, Amandine Jarysta, Matthew Day, Alisha Beirl, Michaela Flonard, Basile Tarchini

Nat Commun. 2021; 12: 2861. Published online 2021 May 17. doi: 10.1038/s41467-021-22997-1

PMCID:: PMC8129141

Abstract Article PDF–12M

Select item 81091939.

Atypical protein kinase C is essential for embryonic vascular development in mice

Zee Chen, Yaoyun Duan, Hong Wang, Huayuan Tang, Shijia Wang, Xinru Wang, Jie Liu, Xi Fang, Kunfu Ouyang

Genesis. Author manuscript; available in PMC 2021 May 10.

Published in final edited form as: Genesis. 2021 Mar; 59(3): e23412. Published online 2021 Feb 6. doi: 10.1002/dvg.23412

PMCID:: PMC8109193

Abstract Article PDF–1.3M

Select item 810850810.

The cell polarity kinase Par1b/MARK2 activation selects specific NF-kB transcripts via phosphorylation of core mediator Med17/TRAP80

Anastasia Mashukova, Radia Forteza, Viraj N. Shah, Pedro J. Salas

Mol Biol Cell. 2021 Apr 15; 32(8): 690–702. doi: 10.1091/mbc.E20-10-0646

PMCID:: PMC8108508

Abstract Article PDF–3.7M

Select item 798842711.

FoxL1⁺ mesenchymal cells are a critical source of Wnt5a for midgut elongation during mouse embryonic intestinal development

Ayano Kondo, Klaus H. Kaestner

Cells Dev. Author manuscript; available in PMC 2022 Mar 1.

Published in final edited form as: Cells Dev. 2021 Mar; 165: 203662. Published online 2021 Jan 28. doi: 10.1016/j.cdev.2021.203662

PMCID:: PMC7988427

Abstract Article PDF–2.7M

Select item 793877012.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 785601113.

Stromal upregulation of SOX2 promotes tumorigenesis through the generation of a SFRP1/2-expressing cancer-associated fibroblast population

Hiroaki Kasashima, Angeles Duran, Anxo Martinez-Ordoñez, Yuki Nakanishi, Hiroto Kinoshita, Juan F. Linares, Miguel Reina-Campos, Yotaro Kudo, Antoine L’Hermitte, Masakazu Yashiro, Masaichi Ohira, Fei Bao, Daniele V.F. Tauriello, Eduard Batlle, Maria T. Diaz-Meco, Jorge Moscat

Dev Cell. Author manuscript; available in PMC 2022 Jan 11.

Published in final edited form as: Dev Cell. 2021 Jan 11; 56(1): 95–110.e10. Published online 2020 Nov 17. doi: 10.1016/j.devcel.2020.10.014

PMCID:: PMC7856011

Abstract Article PDF–3.5M

Select item 778866314.

Transmembrane and Immunoglobulin Domain Containing 1, a Putative Tumor Suppressor, Induces G2/M Cell Cycle Checkpoint Arrest in Colon Cancer Cells

Kyle O.C. De La Cena, Rachel X.-Y. Ho, Razie Amraei, Nick Woolf, Joseph Y. Tashjian, Qing Zhao, Sean Richards, Josh Walker, Juanni Huang, Vipul C. Chitalia, Nader Rahimi

Am J Pathol. 2021 Jan; 191(1): 157–167. doi: 10.1016/j.ajpath.2020.09.015

PMCID:: PMC7788663

Abstract Article PDF–3.0M

Select item 742369015.

PKCλ/ι loss induces autophagy, oxidative phosphorylation, and NRF2 to promote liver cancer progression

Yotaro Kudo, Masayuki Sugimoto, Esperanza Arias, Hiroaki Kasashima, Thekla Cordes, Juan F. Linares, Angeles Duran, Yuki Nakanishi, Naoko Nakanishi, Antoine L’Hermitte, Alex Campos, Nadia Senni, Tarmo Rooslid, Lewis R. Roberts, Ana Maria Cuervo, Christian M. Metallo, Michael Karin, Maria T. Diaz-Meco, Jorge Moscat

Cancer Cell. Author manuscript; available in PMC 2021 Aug 10.

Published in final edited form as: Cancer Cell. 2020 Aug 10; 38(2): 247–262.e11. Published online 2020 Jun 25. doi: 10.1016/j.ccell.2020.05.018

PMCID:: PMC7423690

Abstract Article PDF–3.7M

Select item 732203316.

Atypical protein kinase C iota (PKCλ/ι) ensures mammalian development by establishing the maternal–fetal exchange interface

Bhaswati Bhattacharya, Pratik Home, Avishek Ganguly, Soma Ray, Ananya Ghosh, Md. Rashedul Islam, Valerie French, Courtney Marsh, Sumedha Gunewardena, Hiroaki Okae, Takahiro Arima, Soumen Paul

Proc Natl Acad Sci U S A. 2020 Jun 23; 117(25): 14280–14291. Published online 2020 Jun 8. doi: 10.1073/pnas.1920201117

PMCID:: PMC7322033

Abstract Article PDF–3.4M

Select item 721376017.

The actin-cytoskeleton linker protein ezrin is regulated during osteosarcoma metastasis by PKC

L Ren, SH Hong, J Cassavaugh, T Osborne, AJ Chou, SY Kim, R Gorlick, SM Hewitt, C Khanna

Oncogene. Author manuscript; available in PMC 2020 May 11.

Published in final edited form as: Oncogene. 2009 Feb 12; 28(6): 792–802. Published online 2008 Dec 8. doi: 10.1038/onc.2008.437

PMCID:: PMC7213760

Abstract Article PDF–2.0M

Select item 710874618.

Crumbs2 mediates ventricular layer remodelling to form the spinal cord central canal

Christine M. Tait, Kavitha Chinnaiya, Elizabeth Manning, Mariyam Murtaza, John-Paul Ashton, Nicholas Furley, Chris J. Hill, C. Henrique Alves, Jan Wijnholds, Kai S. Erdmann, Andrew Furley, Penny Rashbass, Raman M. Das, Kate G. Storey, Marysia Placzek

PLoS Biol. 2020 Mar; 18(3): e3000470. Published online 2020 Mar 9. doi: 10.1371/journal.pbio.3000470

PMCID:: PMC7108746

Abstract Article PDF–4.7M

Select item 692605119.

WNT/RYK signaling restricts goblet cell differentiation during lung development and repair

Hyun-Taek Kim, Wenguang Yin, Yuko Nakamichi, Paolo Panza, Beate Grohmann, Carmen Buettner, Stefan Guenther, Clemens Ruppert, Yasuhiro Kobayashi, Andreas Guenther, Didier Y. R. Stainier

Proc Natl Acad Sci U S A. 2019 Dec 17; 116(51): 25697–25706. Published online 2019 Nov 27. doi: 10.1073/pnas.1911071116

PMCID:: PMC6926051

Abstract Article PDF–2.9M

Select item 672691020.

Proteostasis is essential during cochlear development for neuron survival and hair cell polarity

Stephen Freeman, Susana Mateo Sánchez, Ronald Pouyo, Pierre‐Bernard Van Lerberghe, Kevin Hanon, Nicolas Thelen, Marc Thiry, Giovanni Morelli, Laura Van Hees, Sophie Laguesse, Alain Chariot, Laurent Nguyen, Laurence Delacroix, Brigitte Malgrange

EMBO Rep. 2019 Sep; 20(9): e47097. Published online 2019 Jul 19. doi: 10.15252/embr.201847097

PMCID:: PMC6726910

Abstract Article PDF–16M

PMC

Result Filters

Article attributes

Text availability

Publication date

Custom date range

Research Funder

Additional filters

Display Settings:

Send to:

Links from GEO Profiles

Items: 1 to 20 of 150

Display Settings:

Send to:

Supplemental Content

Find related data

Recent activity