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Items: 1 to 20 of 36

1.
Viral protein engagement of GBF1 induces host cell vulnerability through synthetic lethality
Arti T. Navare, Fred D. Mast, Jean Paul Olivier, Thierry Bertomeu, Maxwell L. Neal, Lindsay N. Carpp, Alexis Kaushansky, Jasmin Coulombe-Huntington, Mike Tyers, John D. Aitchison
J Cell Biol. 2022 Nov 7; 221(11): e202011050. Published online 2022 Oct 28. doi: 10.1083/jcb.202011050
PMCID:
PMC9623979
AbstractArticlePDF–3.7M
2.
Quantitative Interaction Proteomics of Neurodegenerative Disease Proteins
Fabian Hosp, Hannes Vossfeldt, Matthias Heinig, Djordje Vasiljevic, Anup Arumughan, Emanuel Wyler, Genetic and Environmental Risk for Alzheimer’s Disease (GERAD1) Consortium, Markus Landthaler, Norbert Hubner, Erich E. Wanker, Lars Lannfelt, Martin Ingelsson, Maciej Lalowski, Aaron Voigt, Matthias Selbach
Cell Rep. Author manuscript; available in PMC 2022 Apr 18.
Published in final edited form as: Cell Rep. 2015 May 19; 11(7): 1134–1146. Published online 2015 May 7. doi: 10.1016/j.celrep.2015.04.030
PMCID:
PMC9014711
AbstractArticlePDF–2.2M
3.
SARS‐CoV‐2–host proteome interactions for antiviral drug discovery
Xiaonan Liu, Sini Huuskonen, Tuomo Laitinen, Taras Redchuk, Mariia Bogacheva, Kari Salokas, Ina Pöhner, Tiina Öhman, Arun Kumar Tonduru, Antti Hassinen, Lisa Gawriyski, Salla Keskitalo, Maria K Vartiainen, Vilja Pietiäinen, Antti Poso, Markku Varjosalo
Mol Syst Biol. 2021 Nov; 17(11): e10396. Published online 2021 Oct 28. doi: 10.15252/msb.202110396
PMCID:
PMC8552907
AbstractArticlePDF–3.9M
4.
KDELR2 promotes breast cancer proliferation via HDAC3‐mediated cell cycle progression
Haoran Wei, Wenhao Ma, Xiaofei Lu, Haiying Liu, Kashuai Lin, Yinghui Wang, Zijian Ye, Linchong Sun, Zhitong Huang, Tingting Pan, Zilong Zhou, Eric Y. Cheng, Huafeng Zhang, Ping Gao, Xiuying Zhong
Cancer Commun (Lond) 2021 Sep; 41(9): 904–920. Published online 2021 Jun 19. doi: 10.1002/cac2.12180
PMCID:
PMC8441056
AbstractArticlePDF–5.8M
5.
Two novel bi‐allelic KDELR2 missense variants cause osteogenesis imperfecta with neurodevelopmental features
Stephanie Efthymiou, Isabella Herman, Fatima Rahman, Najwa Anwar, Reza Maroofian, Janice Yip, Tadahiro Mitani, Daniel G. Calame, Jill V. Hunter, V. Reid Sutton, Elif Yilmaz Gulec, Ruizhi Duan, Jawid M. Fatih, Dana Marafi, Davut Pehlivan, Shalini N. Jhangiani, Richard A. Gibbs, Jennifer E. Posey, SYNAPS Study Group, Shazia Maqbool, James R. Lupski, Henry Houlden
Am J Med Genet A. 2021 Jul; 185(7): 2241–2249. Published online 2021 May 8. doi: 10.1002/ajmg.a.62221
PMCID:
PMC8436746
ArticlePDF–2.0M
6.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
7.
GREB1: An evolutionarily conserved protein with a glycosyltransferase domain links ERα glycosylation and stability to cancer
Eun Myoung Shin, Vinh Thang Huynh, Sultan Abda Neja, Chia Yi Liu, Anandhkumar Raju, Kelly Tan, Nguan Soon Tan, Jayantha Gunaratne, Xuezhi Bi, Lakshminarayan M. Iyer, L. Aravind, Vinay Tergaonkar
Sci Adv. 2021 Mar; 7(12): eabe2470. Published online 2021 Mar 17. doi: 10.1126/sciadv.abe2470
PMCID:
PMC7968844
AbstractArticlePDF–1.1M
8.
Interaction between KDELR2 and HSP47 as a Key Determinant in Osteogenesis Imperfecta Caused by Bi-allelic Variants in KDELR2
Fleur S. van Dijk, Oliver Semler, Julia Etich, Anna Köhler, Juan A. Jimenez-Estrada, Nathalie Bravenboer, Lauria Claeys, Elise Riesebos, Sejla Gegic, Sander R. Piersma, Connie R. Jimenez, Quinten Waisfisz, Carmen-Lisset Flores, Julian Nevado, Arjan J. Harsevoort, Guus J.M. Janus, Anton A.M. Franken, Astrid M. van der Sar, Hanne Meijers-Heijboer, Karen E. Heath, Pablo Lapunzina, Peter G.J. Nikkels, Gijs W.E. Santen, Julian Nüchel, Markus Plomann, Raimund Wagener, Mirko Rehberg, Heike Hoyer-Kuhn, Elisabeth M.W. Eekhoff, Gerard Pals, Matthias Mörgelin, Simon Newstead, Brian T. Wilson, Victor L. Ruiz-Perez, Alessandra Maugeri, Christian Netzer, Frank Zaucke, Dimitra Micha
Am J Hum Genet. 2020 Nov 5; 107(5): 989–999. Published online 2020 Oct 13. doi: 10.1016/j.ajhg.2020.09.009
PMCID:
PMC7675035
AbstractArticlePDF–2.7M
9.
Cell-type-specific differences in KDEL receptor clustering in mammalian cells
Achim Bauer, Ludger Santen, Manfred J. Schmitt, M. Reza Shaebani, Björn Becker
PLoS One. 2020; 15(7): e0235864. Published online 2020 Jul 9. doi: 10.1371/journal.pone.0235864
PMCID:
PMC7347126
AbstractArticlePDF–1.8M
10.
Loss-of-Function Variants in TBC1D32 Underlie Syndromic Hypopituitarism
Johanna Hietamäki, Louise C Gregory, Sandy Ayoub, Anna-Pauliina Iivonen, Kirsi Vaaralahti, Xiaonan Liu, Nina Brandstack, Andrew J Buckton, Tiina Laine, Johanna Känsäkoski, Matti Hero, Päivi J Miettinen, Markku Varjosalo, Emma Wakeling, Mehul T Dattani, Taneli Raivio
J Clin Endocrinol Metab. 2020 Jun; 105(6): 1748–1758. Published online 2020 Feb 15. doi: 10.1210/clinem/dgaa078
PMCID:
PMC7138537
AbstractArticle
11.
A brefeldin A-like phenotype is induced by the overexpression of a human ERD-2-like protein, ELP-1
Victor W. Hsu, Nicky Shah, Richard D. Klausner
Cell. 1992 May 15; 69(4): 625–635. Published online 2004 Apr 16. doi: 10.1016/0092-8674(92)90226-3
PMCID:
PMC7133352
AbstractArticlePDF–2.7M
12.
Proteomic Analysis Reveals a Role for RSK in p120-catenin Phosphorylation and Melanoma Cell-Cell Adhesion
Antoine Méant, Beichen Gao, Geneviève Lavoie, Sami Nourreddine, Flora Jung, Léo Aubert, Joseph Tcherkezian, Anne-Claude Gingras, Philippe P. Roux
Mol Cell Proteomics. 2020 Jan; 19(1): 50–64. Published online 2019 Nov 2. doi: 10.1074/mcp.RA119.001811
PMCID:
PMC6944238
AbstractArticlePDF–5.7M
13.
KDEL receptor regulates secretion by lysosome relocation- and autophagy-dependent modulation of lipid-droplet turnover
Diego Tapia, Tomás Jiménez, Constanza Zamora, Javier Espinoza, Riccardo Rizzo, Alexis González-Cárdenas, Danitza Fuentes, Sergio Hernández, Viviana A. Cavieres, Andrea Soza, Fanny Guzmán, Gloria Arriagada, María Isabel Yuseff, Gonzalo A. Mardones, Patricia V. Burgos, Alberto Luini, Alfonso González, Jorge Cancino
Nat Commun. 2019; 10: 735. Published online 2019 Feb 13. doi: 10.1038/s41467-019-08501-w
PMCID:
PMC6374470
AbstractArticlePDF–8.8M
14.
KDELR2 Competes with Measles Virus Envelope Proteins for Cellular Chaperones Reducing Their Chaperone-Mediated Cell Surface Transport
Vishakha Tiwarekar, Markus Fehrholz, Jürgen Schneider-Schaulies
Viruses. 2019 Jan; 11(1): 27. Published online 2019 Jan 4. doi: 10.3390/v11010027
PMCID:
PMC6356275
AbstractArticlePDF–2.1M
15.
CRISPR/Cas9-mediated Genomic Editing of Cluap1/IFT38 Reveals a New Role in Actin Arrangement
Tina Beyer, Sylvia Bolz, Katrin Junger, Nicola Horn, Muhammad Moniruzzaman, Yasmin Wissinger, Marius Ueffing, Karsten Boldt
Mol Cell Proteomics. 2018 Jul; 17(7): 1285–1294. Published online 2018 Apr 3. doi: 10.1074/mcp.RA117.000487
PMCID:
PMC6030719
AbstractArticlePDF–2.7M
16.
RNA-binding activity of TRIM25 is mediated by its PRY/SPRY domain and is required for ubiquitination
Nila Roy Choudhury, Gregory Heikel, Maryia Trubitsyna, Peter Kubik, Jakub Stanislaw Nowak, Shaun Webb, Sander Granneman, Christos Spanos, Juri Rappsilber, Alfredo Castello, Gracjan Michlewski
BMC Biol. 2017; 15: 105. Published online 2017 Nov 8. doi: 10.1186/s12915-017-0444-9
PMCID:
PMC5678581
AbstractArticlePDF–3.2M
17.
Prohibitin 1 regulates tumor cell apoptosis via the interaction with X-linked inhibitor of apoptosis protein
Yingjie Xu, Wen Yang, Jinjun Shi, Bruce R. Zetter
J Mol Cell Biol. 2016 Jun; 8(3): 282–285. Published online 2016 Jul 7. doi: 10.1093/jmcb/mjw018
PMCID:
PMC5525133
ArticlePDF–1.9M
18.
Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing
Teng Fei, Yiwen Chen, Tengfei Xiao, Wei Li, Laura Cato, Peng Zhang, Maura B. Cotter, Michaela Bowden, Rosina T. Lis, Shuang G. Zhao, Qiu Wu, Felix Y. Feng, Massimo Loda, Housheng Hansen He, X. Shirley Liu, Myles Brown
Proc Natl Acad Sci U S A. 2017 Jun 27; 114(26): E5207–E5215. Published online 2017 Jun 13. doi: 10.1073/pnas.1617467114
PMCID:
PMC5495225
AbstractArticlePDF–1.3M
19.
The OncoPPi network of cancer-focused protein–protein interactions to inform biological insights and therapeutic strategies
Zenggang Li, Andrei A. Ivanov, Rina Su, Valentina Gonzalez-Pecchi, Qi Qi, Songlin Liu, Philip Webber, Elizabeth McMillan, Lauren Rusnak, Cau Pham, Xiaoqian Chen, Xiulei Mo, Brian Revennaugh, Wei Zhou, Adam Marcus, Sahar Harati, Xiang Chen, Margaret A. Johns, Michael A. White, Carlos S. Moreno, Lee A. D. Cooper, Yuhong Du, Fadlo R. Khuri, Haian Fu
Nat Commun. 2017; 8: 14356. Published online 2017 Feb 16. doi: 10.1038/ncomms14356
Correction in:
Nat Commun. 2017; 8: 15350.
PMCID:
PMC5316855
AbstractArticlePDF–4.1M
20.
A dynamic protein interaction landscape of the human centrosome-cilium interface
Gagan D. Gupta, Étienne Coyaud, João Gonçalves, Bahareh A. Mojarad, Yi Liu, Qianzhu Wu, Ladan Gheiratmand, David Comartin, Johnny M. Tkach, Sally W.T. Cheung, Mikhail Bashkurov, Monica Hasegan, James D. Knight, Zhen-Yuan Lin, Markus Schueler, Friedhelm Hildebrandt, Jason Moffat, Anne-Claude Gingras, Brian Raught, Laurence Pelletier
Cell. Author manuscript; available in PMC 2016 Dec 3.
Published in final edited form as: Cell. 2015 Dec 3; 163(6): 1484–1499. doi: 10.1016/j.cell.2015.10.065
PMCID:
PMC5089374
AbstractArticlePDF–1.5M

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