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Select item 111588461.

Haploinsufficiency and acquired loss of Bcl11b and H2AX induces blast crisis of chronic myelogenous leukemia in a transgenic mouse model

Akiko Nagamachi, Norimasa Yamasaki, Kazuko Miyazaki, Hideaki Oda, Masaki Miyazaki, Zen‐ichiro Honda, Ryo Kominami, Toshiya Inaba, Hiroaki Honda

Cancer Sci. 2009 Jul; 100(7): 1219–1226. Published online 2009 Mar 27. doi: 10.1111/j.1349-7006.2009.01172.x

PMCID:: PMC11158846

Abstract Article PDF–2.7M

Select item 110594082.

Atypical heat shock transcription factor HSF5 is critical for male meiotic prophase under non-stress conditions

Saori Yoshimura, Ryuki Shimada, Koji Kikuchi, Soichiro Kawagoe, Hironori Abe, Sakie Iisaka, Sayoko Fujimura, Kei-ichiro Yasunaga, Shingo Usuki, Naoki Tani, Takashi Ohba, Eiji Kondoh, Tomohide Saio, Kimi Araki, Kei-ichiro Ishiguro

Nat Commun. 2024; 15: 3330. Published online 2024 Apr 29. doi: 10.1038/s41467-024-47601-0

PMCID:: PMC11059408

Abstract Article PDF–8.4M

Select item 110154973.

Y chromosome damage underlies testicular abnormalities in ATR-X syndrome

Nayla Y. León, Thanh Nha Uyen Le, Andrew Garvie, Lee H. Wong, Stefan Bagheri-Fam, Vincent R. Harley

iScience. 2024 May 17; 27(5): 109629. Published online 2024 Mar 28. doi: 10.1016/j.isci.2024.109629

PMCID:: PMC11015497

Abstract Article PDF–4.6M

Select item 109402944.

Regulation of meiotic telomere dynamics through membrane fluidity promoted by AdipoR2-ELOVL2

Jingjing Zhang, Mario Ruiz, Per-Olof Bergh, Marcus Henricsson, Nena Stojanović, Ranjan Devkota, Marius Henn, Mohammad Bohlooly-Y, Abrahan Hernández-Hernández, Manfred Alsheimer, Jan Borén, Marc Pilon, Hiroki Shibuya

Nat Commun. 2024; 15: 2315. Published online 2024 Mar 14. doi: 10.1038/s41467-024-46718-6

PMCID:: PMC10940294

Abstract Article PDF–6.0M

Select item 108532165.

Compromised transcription-mRNA export factor THOC2 causes R-loop accumulation, DNA damage and adverse neurodevelopment

Rudrarup Bhattacharjee, Lachlan A. Jolly, Mark A. Corbett, Ing Chee Wee, Sushma R. Rao, Alison E. Gardner, Tarin Ritchie, Eline J. H. van Hugte, Ummi Ciptasari, Sandra Piltz, Jacqueline E. Noll, Nazzmer Nazri, Clare L. van Eyk, Melissa White, Dani Fornarino, Cathryn Poulton, Gareth Baynam, Lyndsey E. Collins-Praino, Marten F. Snel, Nael Nadif Kasri, Kim M. Hemsley, Paul Q. Thomas, Raman Kumar, Jozef Gecz

Nat Commun. 2024; 15: 1210. Published online 2024 Feb 8. doi: 10.1038/s41467-024-45121-5

PMCID:: PMC10853216

Abstract Article PDF–11M

Select item 107535876.

Loss of NR5A1 in mouse Sertoli cells after sex determination changes cellular identity and induces cell death by anoikis

Sirine Souali-Crespo, Diana Condrea, Nadège Vernet, Betty Féret, Muriel Klopfenstein, Erwan Grandgirard, Violaine Alunni, Marie Cerciat, Matthieu Jung, Chloé Mayere, Serge Nef, Manuel Mark, Frédéric Chalmel, Norbert B. Ghyselinck

Development. 2023 Dec 15; 150(24): dev201710. Published online 2023 Dec 11. doi: 10.1242/dev.201710

PMCID:: PMC10753587

Abstract Article

Select item 106864697.

Loss of Aspm causes increased apoptosis of developing neural cells during mouse cerebral corticogenesis

Madoka Tonosaki, Akira Fujimori, Takeshi Yaoi, Kyoko Itoh

PLoS One. 2023; 18(11): e0294893. Published online 2023 Nov 29. doi: 10.1371/journal.pone.0294893

PMCID:: PMC10686469

Abstract Article PDF–3.0M

Select item 106541018.

Transgenerational epigenetic effects imposed by neonicotinoid thiacloprid exposure

Ouzna Dali, Shereen D’Cruz, Louis Legoff, Mariam Diba Lahmidi, Celine Heitz, Pierre-Etienne Merret, Pierre-Yves Kernanec, Farzad Pakdel, Fatima Smagulova

Life Sci Alliance. 2024 Feb; 7(2): e202302237. Published online 2023 Nov 16. doi: 10.26508/lsa.202302237

PMCID:: PMC10654101

Abstract Article PDF–3.1M

Select item 106028899.

P53 independent pathogenic mechanisms contribute to BubR1 microcephaly

Noelle A. Sterling, Bethany K. Terry, Julia M. McDonnell, Seonhee Kim

Front Cell Dev Biol. 2023; 11: 1282182. Published online 2023 Oct 12. doi: 10.3389/fcell.2023.1282182

PMCID:: PMC10602889

Abstract Article PDF–7.3M

Select item 1047875310.

Lem2 is essential for cardiac development by maintaining nuclear integrity

Jacob A Ross, Nathaly Arcos-Villacis, Edmund Battey, Cornelis Boogerd, Constanza Avalos Orellana, Emilie Marhuenda, Pamela Swiatlowska, Didier Hodzic, Fabrice Prin, Tim Mohun, Norman Catibog, Olga Tapia, Larry Gerace, Thomas Iskratsch, Ajay M Shah, Matthew J Stroud

Cardiovasc Res. 2023 Aug; 119(11): 2074–2088. Published online 2023 Apr 17. doi: 10.1093/cvr/cvad061

PMCID:: PMC10478753

Abstract Article PDF–33M

Select item 1045619211.

Helicase-like transcription factor (Hltf)-deletion activates Hmgb1-Rage axis and granzyme A-mediated killing of pancreatic β cells resulting in neonatal lethality

Gurvinder Kaur, Rebecca A. Helmer, Dalia Martinez-Marin, Souad R. Sennoune, Rachel L. Washburn, Raul Martinez-Zaguilan, Jannette M. Dufour, Beverly S. Chilton

PLoS One. 2023; 18(8): e0286109. Published online 2023 Aug 25. doi: 10.1371/journal.pone.0286109

PMCID:: PMC10456192

Abstract Article PDF–3.7M

Select item 1040980012.

SNIP1 and PRC2 coordinate cell fates of neural progenitors during brain development

Yurika Matsui, Mohamed Nadhir Djekidel, Katherine Lindsay, Parimal Samir, Nina Connolly, Gang Wu, Xiaoyang Yang, Yiping Fan, Beisi Xu, Jamy C. Peng

Nat Commun. 2023; 14: 4754. Published online 2023 Aug 8. doi: 10.1038/s41467-023-40487-4

PMCID:: PMC10409800

Abstract Article PDF–5.3M

Select item 1030958913.

Myc promotes polyploidy in murine trophoblast cells and suppresses senescence

Vijay Pratap Singh, Huzaifa Hassan, Fengyan Deng, Dai Tsuchiya, Sean McKinney, Kevin Ferro, Jennifer L. Gerton

Development. 2023 Jun 1; 150(11): dev201581. Published online 2023 Jun 6. doi: 10.1242/dev.201581

PMCID:: PMC10309589

Abstract Article

Select item 1029964114.

The Role of Annexin A1 in DNA Damage Response in Placental Cells: Impact on Gestational Diabetes Mellitus

Jusciele Brogin Moreli, Mayk Ricardo dos Santos, Iracema de Mattos Paranhos Calderon, Cristina Bichels Hebeda, Sandra Helena Poliselli Farsky, Estela Bevilacqua, Sonia Maria Oliani

Int J Mol Sci. 2023 Jun; 24(12): 10155. Published online 2023 Jun 15. doi: 10.3390/ijms241210155

PMCID:: PMC10299641

Abstract Article PDF–11M

Select item 1029933215.

Nerve Injury-Induced γH2AX Reduction in Primary Sensory Neurons Is Involved in Neuropathic Pain Processing

Yan Zhang, Hao Gong, Ji-Shuai Wang, Meng-Na Li, De-Li Cao, Jun Gu, Lin-Xia Zhao, Xin-Dan Zhang, Yu-Tao Deng, Fu-Lu Dong, Yong-Jing Gao, Wen-Xing Sun, Bao-Chun Jiang

Int J Mol Sci. 2023 Jun; 24(12): 10148. Published online 2023 Jun 15. doi: 10.3390/ijms241210148

PMCID:: PMC10299332

Abstract Article PDF–22M

Select item 1028856016.

Trophoblast PR-SET7 dysfunction induces viral mimicry response and necroptosis associated with recurrent miscarriage

Xiaobo Zhou, Yingchun Xu, Shengnan Ren, Ningjie Yang, Yang Sun, Qibing Yang, Yue Zhang, Han Cai, Wenbo Deng, Jingsi Chen, Dunjin Chen, Bin Cao, Hongbo Qi, Haibin Wang, Jinhua Lu

Proc Natl Acad Sci U S A. 2023 Jun 20; 120(25): e2216206120. Published online 2023 Jun 12. doi: 10.1073/pnas.2216206120

PMCID:: PMC10288560

Abstract Article PDF–9.6M

Select item 1028770017.

Maternal NAT10 orchestrates oocyte meiotic cell-cycle progression and maturation in mice

Xue Jiang, Yu Cheng, Yuzhang Zhu, Caoling Xu, Qiaodan Li, Xuemei Xing, Wenqing Li, Jiaqi Zou, Lan Meng, Muhammad Azhar, Yuzhu Cao, Xianhong Tong, Weibing Qin, Xiaoli Zhu, Jianqiang Bao

Nat Commun. 2023; 14: 3729. Published online 2023 Jun 22. doi: 10.1038/s41467-023-39256-0

PMCID:: PMC10287700

Abstract Article PDF–13M

Select item 1023371518.

The exon junction complex component EIF4A3 is essential for mouse and human cortical progenitor mitosis and neurogenesis

Bianca M. Lupan, Rachel A. Solecki, Camila M. Musso, Fernando C. Alsina, Debra L. Silver

Development. 2023 May 15; 150(10): dev201619. Published online 2023 May 26. doi: 10.1242/dev.201619

PMCID:: PMC10233715

Abstract Article

Select item 1016458219.

SPIDR is required for homologous recombination during mammalian meiosis

Tao Huang, Xinyue Wu, Shiyu Wang, Ziyou Bao, Yanling Wan, Ziqi Wang, Mengjing Li, Xiaochen Yu, Yue Lv, Zhaojian Liu, Xiangfeng Chen, Wai-Yee Chan, Fei Gao, Gang Lu, Zi-Jiang Chen, Hongbin Liu

Nucleic Acids Res. 2023 May 8; 51(8): 3855–3868. Published online 2023 Mar 20. doi: 10.1093/nar/gkad154

PMCID:: PMC10164582

Abstract Article PDF–11M

Select item 1013048720.

DNA Methylation–Dependent Restriction of Tyrosine Hydroxylase Contributes to Pancreatic β-Cell Heterogeneity

Nazia Parveen, Jean Kimi Wang, Supriyo Bhattacharya, Janielle Cuala, Mohan Singh Rajkumar, Alexandra E. Butler, Xiwei Wu, Hung-Ping Shih, Senta K. Georgia, Sangeeta Dhawan

Diabetes. 2023 May; 72(5): 575–589. Published online 2023 Jan 6. doi: 10.2337/db22-0506

Correction in:: Diabetes. 2023 Dec; 72(12): 1882.

PMCID:: PMC10130487

Abstract Article PDF–1.8M

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