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Items: 1 to 20 of 992

1.
The relationship between high ratios of CD4/FOXP3 and CD8/CD163 and the improved survivability of metastatic triple-negative breast cancer patients: a multicenter cohort study
Jeffry Beta Tenggara, Andhika Rachman, Joedo Prihartono, Lisnawati Rachmadi, Sonar Soni Panigoro, Didik Setyo Heriyanto, Noorwati Sutandyo, Intan Russianna Nasution, Familia Bella Rahadiati, Ricci Steven, Rachelle Betsy, Samuel Juanputra, Aru Wisaksono Sudoyo
BMC Res Notes. 2024; 17: 44. Published online 2024 Feb 2. doi: 10.1186/s13104-024-06704-z
PMCID:
PMC10835864
AbstractArticlePDF–1.0M
2.
HIV-1 Env trimers asymmetrically engage CD4 receptors in membranes
Wenwei Li, Zhuan Qin, Elizabeth Nand, Michael W. Grunst, Jonathan R. Grover, Julian W. Bess, Jr, Jeffrey D. Lifson, Michael B. Zwick, Hemant D. Tagare, Pradeep D. Uchil, Walther Mothes
Nature. 2023; 623(7989): 1026–1033. Published online 2023 Nov 22. doi: 10.1038/s41586-023-06762-6
PMCID:
PMC10686830
AbstractArticlePDF–14M
3.
Intermediate conformations of CD4-bound HIV-1 Env heterotrimers
Kim-Marie A. Dam, Chengcheng Fan, Zhi Yang, Pamela J. Bjorkman
Nature. 2023; 623(7989): 1017–1025. Published online 2023 Nov 22. doi: 10.1038/s41586-023-06639-8
Correction in:
Nature. 2024; 626(7998): E7.
PMCID:
PMC10686819
AbstractArticlePDF–12M
4.
Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity
Martin Golkowski, Andrea Lius, Tanmay Sapre, Ho-Tak Lau, Taylor Moreno, Dustin J. Maly, Shao-En Ong
Mol Cell. Author manuscript; available in PMC 2023 Apr 4.
Published in final edited form as: Mol Cell. 2023 Mar 2; 83(5): 803–818.e8. Published online 2023 Feb 2. doi: 10.1016/j.molcel.2023.01.015
PMCID:
PMC10072906
AbstractArticlePDF–4.2M
5.
AP-2 Adaptor Complex-Dependent Enhancement of HIV-1 Replication by Nef in the Absence of the Nef/AP-2 Targets SERINC5 and CD4
Balaji Olety, Yoshiko Usami, Yuanfei Wu, Paul Peters, Heinrich Göttlinger
mBio. 2023 Jan-Feb; 14(1): e03382-22. Published online 2023 Jan 9. doi: 10.1128/mbio.03382-22
PMCID:
PMC9973267
AbstractArticlePDF–3.5M
6.
Lack of Association between Common LAG3/CD4 Variants and Risk of Migraine
Elena García-Martín, Santiago Navarro-Muñoz, Pedro Ayuso, Christopher Rodríguez, Mercedes Serrador, Hortensia Alonso-Navarro, Marisol Calleja, Francisco Navacerrada, Laura Turpín-Fenoll, Marta Recio-Bermejo, Rafael García-Ruiz, Jorge Millán-Pascual, José Francisco Plaza-Nieto, Esteban García-Albea, José A. G. Agúndez, Félix Javier Jiménez-Jiménez
Int J Mol Sci. 2023 Jan; 24(2): 1292. Published online 2023 Jan 9. doi: 10.3390/ijms24021292
PMCID:
PMC9866744
AbstractArticlePDF–270K
7.
Association between LAG3/CD4 gene variants and risk of Parkinson's disease
Elena García‐Martín, Pau Pastor, Javier Gómez‐Tabales, Hortensia Alonso‐Navarro, Ignacio Alvarez, Mariateresa Buongiorno, Maria de las Olas Cerezo‐Arias, Miquel Aguilar, José A. G. Agúndez, Félix Javier Jiménez‐Jiménez
Eur J Clin Invest. 2022 Nov; 52(11): e13847. Published online 2022 Aug 5. doi: 10.1111/eci.13847
PMCID:
PMC9787747
AbstractArticlePDF–255K
8.
LAG3/CD4 Genes Variants and the Risk for Restless Legs Syndrome
Félix Javier Jiménez-Jiménez, Javier Gómez-Tabales, Hortensia Alonso-Navarro, Christopher Rodríguez, Laura Turpín-Fenoll, Jorge Millán-Pascual, Ignacio Álvarez, Pau Pastor, Marisol Calleja, Rafael García-Ruiz, Santiago Navarro-Muñoz, Marta Recio-Bermejo, José Francisco Plaza-Nieto, Esteban García-Albea, Elena García-Martín, José A. G. Agúndez
Int J Mol Sci. 2022 Dec; 23(23): 14795. Published online 2022 Nov 26. doi: 10.3390/ijms232314795
PMCID:
PMC9739762
AbstractArticlePDF–300K
9.
Association between LAG3/CD4 Genes Variants and Risk for Multiple Sclerosis
Elena García-Martín, José A. G. Agúndez, Javier Gómez-Tabales, Julián Benito-León, Jorge Millán-Pascual, María Díaz-Sánchez, Patricia Calleja, Laura Turpín-Fenoll, Hortensia Alonso-Navarro, Esteban García-Albea, José Francisco Plaza-Nieto, Felix Javier Jiménez-Jiménez
Int J Mol Sci. 2022 Dec; 23(23): 15244. Published online 2022 Dec 3. doi: 10.3390/ijms232315244
PMCID:
PMC9735634
AbstractArticlePDF–290K
10.
Oncogenic deubiquitination controls tyrosine kinase signaling and therapy response in acute lymphoblastic leukemia
Qi Jin, Blanca Gutierrez Diaz, Tim Pieters, Yalu Zhou, Sonali Narang, Igor Fijalkwoski, Cristina Borin, Jolien Van Laere, Monique Payton, Byoung-Kyu Cho, Cuijuan Han, Limin Sun, Valentina Serafin, George Yacu, Wouter Von Loocke, Giuseppe Basso, Giulia Veltri, Ingrid Dreveny, Issam Ben-Sahra, Young Ah Goo, Stephanie L. Safgren, Yi-Chien Tsai, Beat Bornhauser, Praveen Kumar Suraneni, Alexandre Gaspar-Maia, Irawati Kandela, Pieter Van Vlierberghe, John D. Crispino, Aristotelis Tsirigos, Panagiotis Ntziachristos
Sci Adv. 2022 Dec; 8(49): eabq8437. Published online 2022 Dec 9. doi: 10.1126/sciadv.abq8437
PMCID:
PMC9733937
AbstractArticlePDF–2.2M
11.
Posttranslational Modifications within the HIV-1 Envelope Glycoprotein Which Restrict Virus Assembly and CD4-Dependent Infection
SHERYL HAGGERTY, MICHAEL P. DEMPSEY, MICHAEL I. BUKRINSKY, LI GUO, MARIO STEVENSON
AIDS Res Hum Retroviruses. Author manuscript; available in PMC 2022 Sep 23.
Published in final edited form as: AIDS Res Hum Retroviruses. 1991 Jun; 7(6): 501–510. doi: 10.1089/aid.1991.7.501
PMCID:
PMC9507334
AbstractArticlePDF–955K
12.
CMV exposure drives long-term CD57+ CD4 memory T-cell inflation following allogeneic stem cell transplant
Albert C. Yeh, Antiopi Varelias, Anupama Reddy, Sierra M. Barone, Stuart D. Olver, Kate Chilson, Lynn E. Onstad, Kathleen S. Ensbey, Andrea S Henden, Luke Samson, Carla A Jaeger, Timothy Bi, Kimberly B. Dahlman, Tae Kon Kim, Ping Zhang, Mariapia A. Degli-Esposti, Evan W. Newell, Madan H. Jagasia, Jonathan M. Irish, Stephanie J. Lee, Geoffrey R. Hill
Blood. 2021 Dec 30; 138(26): 2874–2885. doi: 10.1182/blood.2020009492
PMCID:
PMC8718626
AbstractArticle
13.
Increase of CD4+CD25highFoxP3+ cells impairs in vitro human microbicidal activity against Mycobacterium tuberculosis during latent and acute pulmonary tuberculosis
Lorenzzo Lyrio Stringari, Luciana Polaco Covre, Flávia Dias Coelho da Silva, Vivian Leite de Oliveira, Maria Carolina Campana, David Jamil Hadad, Moisés Palaci, Padmini Salgame, Reynaldo Dietze, Daniel Cláudio de Oliveira Gomes, Rodrigo Ribeiro-Rodrigues
PLoS Negl Trop Dis. 2021 Jul; 15(7): e0009605. Published online 2021 Jul 29. doi: 10.1371/journal.pntd.0009605
PMCID:
PMC8321116
AbstractArticlePDF–1.4M
14.
Lack of intrafollicular memory CD4 + T cells is predictive of early clinical failure in newly diagnosed follicular lymphoma
Patrizia Mondello, Angelo Fama, Melissa C. Larson, Andrew L. Feldman, Jose C. Villasboas, Zhi-Zhang Yang, Ilia Galkin, Viktor Svelolkin, Ekaterina Postovalova, Alexander Bagaev, Pavel Ovcharov, Arina Varlamova, Sarah Huet, Bruno Tesson, Kaitlyn R. McGrath, Susan Slager, Brian K. Link, Sergei Syrbu, Anne J. Novak, Thomas M. Habermann, Thomas E. Witzig, Grzegorz S. Nowakowski, Gilles Salles, James R. Cerhan, Stephen M. Ansell
Blood Cancer J. 2021 Jul; 11(7): 130. Published online 2021 Jul 15. doi: 10.1038/s41408-021-00521-4
PMCID:
PMC8282842
AbstractArticlePDF–4.7M
15.
Serum CD4 Is Associated with the Infiltration of CD4+T Cells in the Tumor Microenvironment of Gastric Cancer
Qi You, Tianyi Fang, Xin Yin, Yimin Wang, Yongheng Yang, Lei Zhang, Yingwei Xue
J Immunol Res. 2021; 2021: 6539702. Published online 2021 Feb 28. doi: 10.1155/2021/6539702
PMCID:
PMC8246328
AbstractArticlePDF–1.5M
16.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
17.
Cryo-EM structures of HIV-1 trimer bound to CD4-mimetics BNM-III-170 and M48U1 adopt a CD4-bound open conformation
Claudia A. Jette, Christopher O. Barnes, Sharon M. Kirk, Bruno Melillo, Amos B. Smith, III, Pamela J. Bjorkman
Nat Commun. 2021; 12: 1950. Published online 2021 Mar 29. doi: 10.1038/s41467-021-21816-x
PMCID:
PMC8007822
AbstractArticlePDF–4.2M
18.
HIV-1 Nef counteracts autophagy restriction by enhancing the association between BECN1 and its inhibitor BCL2 in a PRKN-dependent manner
Sergio Castro-Gonzalez, Yuhang Shi, Marta Colomer-Lluch, Ying Song, Kaitlyn Mowery, Sharilyn Almodovar, Anju Bansal, Frank Kirchhoff, Konstantin Sparrer, Chengyu Liang, Ruth Serra-Moreno
Autophagy. 2021; 17(2): 553–577. Published online 2020 Feb 25. doi: 10.1080/15548627.2020.1725401
PMCID:
PMC8007141
AbstractArticlePDF–5.8M
19.
Significant Redox Insensitivity of the Functions of the SARS-CoV Spike Glycoprotein: COMPARISON WITH HIV ENVELOPE
Dimitri Lavillette, Rym Barbouche, Yongxiu Yao, Bertrand Boson, François-Loïc Cosset, Ian M. Jones, Emmanuel Fenouillet
J Biol Chem. 2006 Apr 7; 281(14): 9200–9204. Published online 2021 Jan 4. doi: 10.1074/jbc.M512529200
PMCID:
PMC7982606
AbstractArticlePDF–353K
20.
Lost in Translation: Lack of CD4 Expression due to a Novel Genetic Defect
Andrea Lisco, Peiying Ye, Chun-Shu Wong, Luxin Pei, Amy P Hsu, Emily M Mace, Jordan S Orange, Silvia Lucena Lage, Addison Jon Ward, Stephen A Migueles, Mark Connors, Megan V Anderson, Clarisa M Buckner, Susan Moir, Adam Rupert, Alina Dulau-Florea, Princess Ogbogu, Dylan Timberlake, Luigi D Notarangelo, Stefania Pittaluga, Roshini S Abraham, Irini Sereti
J Infect Dis. 2021 Feb 15; 223(4): 645–654. Published online 2021 Jan 20. doi: 10.1093/infdis/jiab025
PMCID:
PMC7904290
AbstractArticlePDF–49M

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