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Select item 93786491.

Increased TRIM31 gene expression is positively correlated with SARS-CoV-2 associated genes TMPRSS2 and TMPRSS4 in gastrointestinal cancers

Mehmet Arda Temena, Ahmet Acar

Sci Rep. 2022; 12: 11763. Published online 2022 Aug 15. doi: 10.1038/s41598-022-15911-2

PMCID:: PMC9378649

Abstract Article PDF–4.0M

Select item 89017352.

The E3 ubiquitin ligase TRIM31 plays a critical role in hypertensive nephropathy by promoting proteasomal degradation of MAP3K7 in the TGF-β1 signaling pathway

Jie Zhang, Lei Cao, Xiaohong Wang, Qian Li, Meng Zhang, Cheng Cheng, Liwen Yu, Fei Xue, Wenhai Sui, Shangwen Sun, Na li, Peili Bu, Bingyu Liu, Fei Gao, Junhui Zhen, Guohai Su, Cheng Zhang, Chengjiang Gao, Meng Zhang, Yun Zhang

Cell Death Differ. 2022 Mar; 29(3): 556–567. Published online 2021 Sep 28. doi: 10.1038/s41418-021-00874-0

PMCID:: PMC8901735

Abstract Article PDF–13M

Select item 88816093.

The E3 ubiquitin-protein ligase Trim31 alleviates non-alcoholic fatty liver disease by targeting Rhbdf2 in mouse hepatocytes

Minxuan Xu, Jun Tan, Wei Dong, Benkui Zou, Xuepeng Teng, Liancai Zhu, Chenxu Ge, Xianling Dai, Qin Kuang, Shaoyu Zhong, Lili Lai, Chao Yi, Tingting Tang, Junjie Zhao, Longyan Wang, Jin Liu, Hao Wei, Yan Sun, Qiufeng Yang, Qiang Li, Deshuai Lou, Linfeng Hu, Xi Liu, Gang Kuang, Jing Luo, Mingxin Xiong, Jing Feng, Chufeng Zhang, Bochu Wang

Nat Commun. 2022; 13: 1052. Published online 2022 Feb 25. doi: 10.1038/s41467-022-28641-w

PMCID:: PMC8881609

Abstract Article PDF–7.5M

Select item 85169224.

Loss of TRIM31 promotes breast cancer progression through regulating K48- and K63-linked ubiquitination of p53

Yafei Guo, Qin Li, Gang Zhao, Jie Zhang, Hang Yuan, Tianyu Feng, Deqiong Ou, Rui Gu, Siqi Li, Kai Li, Ping Lin

Cell Death Dis. 2021 Oct; 12(10): 945. Published online 2021 Oct 14. doi: 10.1038/s41419-021-04208-3

PMCID:: PMC8516922

Abstract Article PDF–8.2M

Select item 83429875.

TRIM31 facilitates K27-linked polyubiquitination of SYK to regulate antifungal immunity

Xueer Wang, Honghai Zhang, Zhugui Shao, Wanxin Zhuang, Chao Sui, Feng Liu, Xiaorong Chen, Jinxiu Hou, Lingli Kong, Hansen Liu, Yi Zheng, Bingyu Liu, Tian Chen, Lei Zhang, Xinming Jia, Chengjiang Gao

Signal Transduct Target Ther. 2021; 6: 298. Published online 2021 Aug 6. doi: 10.1038/s41392-021-00711-3

PMCID:: PMC8342987

Abstract Article PDF–6.2M

Select item 82608756.

The E3 ubiquitin ligase TRIM31 is involved in cerebral ischemic injury by promoting degradation of TIGAR

Shenglan Zeng, Ze Zhao, Shengnan Zheng, Mengting Wu, Xiaomeng Song, Yiquan Li, Yi Zheng, Bingyu Liu, Lin Chen, Chengjiang Gao, Huiqing Liu

Redox Biol. 2021 Sep; 45: 102058. Published online 2021 Jun 29. doi: 10.1016/j.redox.2021.102058

PMCID:: PMC8260875

Abstract Article PDF–12M

Select item 81650307.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 81377028.

USP18 positively regulates innate antiviral immunity by promoting K63-linked polyubiquitination of MAVS

Jinxiu Hou, Lulu Han, Ze Zhao, Huiqing Liu, Lei Zhang, Chunhong Ma, Fan Yi, Bingyu Liu, Yi Zheng, Chengjiang Gao

Nat Commun. 2021; 12: 2970. Published online 2021 May 20. doi: 10.1038/s41467-021-23219-4

PMCID:: PMC8137702

Abstract Article PDF–2.2M

Select item 78157199.

MIND bomb 2 prevents RIPK1 kinase activity-dependent and -independent apoptosis through ubiquitylation of cFLIP_L

Osamu Nakabayashi, Hirotaka Takahashi, Kenta Moriwaki, Sachiko Komazawa-Sakon, Fumiaki Ohtake, Shin Murai, Yuichi Tsuchiya, Yuki Koyahara, Yasushi Saeki, Yukiko Yoshida, Soh Yamazaki, Fuminori Tokunaga, Tatsuya Sawasaki, Hiroyasu Nakano

Commun Biol. 2021; 4: 80. Published online 2021 Jan 19. doi: 10.1038/s42003-020-01603-y

PMCID:: PMC7815719

Abstract Article PDF–4.3M

Select item 773348610.

Nasopharyngeal carcinoma MHC region deep sequencing identifies HLA and novel non-HLA TRIM31 and TRIM39 loci

Lvwen Ning, Josephine Mun-Yee Ko, Valen Zhuoyou Yu, Hoi Yan Ng, Candy King-Chi Chan, Lihua Tao, Shiu-Yeung Lam, Merrin Man-Long Leong, Roger Kai-Cheong Ngan, Dora Lai-Wan Kwong, Anne Wing-Mui Lee, Wai-Tong Ng, Ashley Cheng, Stewart Tung, Victor Ho-Fun Lee, Ka-On Lam, Chung-Kong Kwan, Wing-Sum Li, Stephen Yau, Jin-Xin Bei, Maria Li Lung

Commun Biol. 2020; 3: 759. Published online 2020 Dec 11. doi: 10.1038/s42003-020-01487-y

PMCID:: PMC7733486

Abstract Article PDF–2.7M

Select item 764416311.

TRIM31 promotes apoptosis via TAK1-mediated activation of NF-κB signaling in sepsis-induced myocardial dysfunction

Xiaofang Yang, Jingjing Sun, FangYuan Sun, Yulong Yao, Tianning Tian, Jiayi Zhou, Weihong Shen, Ming Lu, Ming Lei

Cell Cycle. 2020; 19(20): 2685–2700. Published online 2020 Oct 4. doi: 10.1080/15384101.2020.1826235

PMCID:: PMC7644163

Abstract Article PDF–7.5M

Select item 730287212.

Virus subtype-specific suppression of MAVS aggregation and activation by PB1-F2 protein of influenza A (H7N9) virus

Pak-Hin Hinson Cheung, Tak-Wang Terence Lee, Chun Kew, Honglin Chen, Kwok-Yung Yuen, Chi-Ping Chan, Dong-Yan Jin

PLoS Pathog. 2020 Jun; 16(6): e1008611. Published online 2020 Jun 8. doi: 10.1371/journal.ppat.1008611

PMCID:: PMC7302872

Abstract Article PDF–5.2M

Select item 716998313.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 716024314.

TRIM31 promotes acute myeloid leukemia progression and sensitivity to daunorubicin through the Wnt/β-catenin signaling

Yi Xiao, Taoran Deng, Xi Ming, Jinhuang Xu

Biosci Rep. 2020 Apr 30; 40(4): BSR20194334. Published online 2020 Apr 15. doi: 10.1042/BSR20194334

PMCID:: PMC7160243

Abstract Article PDF–1.1M

Select item 704117815.

MicroRNA-29c-3p acts as a tumor suppressor gene and inhibits tumor progression in hepatocellular carcinoma by targeting TRIM31

Tao Lv, Li Jiang, Lingxiang Kong, Jiayin Yang

Oncol Rep. 2020 Mar; 43(3): 953–964. Published online 2020 Jan 17. doi: 10.3892/or.2020.7469

PMCID:: PMC7041178

Abstract Article PDF–1.5M

Select item 662723316.

RNF34 functions in immunity and selective mitophagy by targeting MAVS for autophagic degradation

Xiang He, Yongjie Zhu, Yanhong Zhang, Yunqi Geng, Jing Gong, Jin Geng, Pingping Zhang, Xiaotong Zhang, Ning Liu, Yumeng Peng, Chenbin Wang, Yujie Wang, Xin Liu, Luming Wan, Feng Gong, Congwen Wei, Hui Zhong

EMBO J. 2019 Jul 15; 38(14): e100978. Published online 2019 Jun 17. doi: 10.15252/embj.2018100978