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Select item 108556731.

Effect of DIO2 Gene Polymorphism on Thyroid Hormone Levels and Its Correlation with the Severity of Schizophrenia in a Pakistani Population

Farina Hanif, Quratulain Amir, Washdev Washdev

Int J Mol Sci. 2024 Feb; 25(3): 1915. Published online 2024 Feb 5. doi: 10.3390/ijms25031915

PMCID:: PMC10855673

Abstract Article PDF–534K

Select item 105286182.

The polymorphic inheritance of DIO2 rs225014 may predict body weight variation after Graves’ disease treatment

Ana Paula Comarella, Danilo Vilagellin, Natassia Elena Bufalo, Jessica Ferreira Euflauzino, Elisangela de Souza Teixeira, Ana Beatriz Pinotti Pedro Miklos, Roberto Bernardo dos Santos, João H. Romaldini, Laura S. Ward

Arch Endocrinol Metab. 2020 Nov-Dec; 64(6): 787–795. Published online 2020 Oct 9. doi: 10.20945/2359-3997000000295

PMCID:: PMC10528618

Abstract Article PDF–405K

Select item 101048153.

Polymorphisms within DIO2 and GADD45A genes increase the risk of liver disease progression in chronic hepatitis b carriers

Magda Rybicka, Eloi R. Verrier, Thomas F. Baumert, Krzysztof Piotr Bielawski

Sci Rep. 2023; 13: 6124. Published online 2023 Apr 14. doi: 10.1038/s41598-023-32753-8

PMCID:: PMC10104815

Abstract Article PDF–1.2M

Select item 99931094.

Association between DIO2 Thr92Ala polymorphism and hypertension in patients with hypothyroidism: Korean Genome and Epidemiology Study

Young Mi Kang, Bon Seok Koo, Hyon-Seung Yi, Jung Tae Kim, Boyoung Park, Ju Hee Lee, Minho Shong, Yea Eun Kang

Korean J Intern Med. 2023 Mar; 38(2): 226–237. Published online 2023 Jan 17. doi: 10.3904/kjim.2022.292

PMCID:: PMC9993109

Abstract Article PDF–982K

Select item 92260465.

Type 2 deiodinase p.Thr92Ala polymorphism does not affect the severity of obesity and weight loss after bariatric surgery

Nicoletta Benenati, Annalisa Bufano, Silvia Cantara, Claudia Ricci, Carlotta Marzocchi, Cristina Ciuoli, Ida Sannino, Andrea Tirone, Costantino Voglino, Giuseppe Vuolo, Maria Grazia Castagna

Sci Rep. 2022; 12: 10643. Published online 2022 Jun 23. doi: 10.1038/s41598-022-14863-x

PMCID:: PMC9226046

Abstract Article PDF–954K

Select item 88088586.

Patients with Osteoarthritis and Kashin-Beck Disease Display Distinct CpG Methylation Profiles in the DIO2, GPX3, and TXRND1 Promoter Regions

Rongqiang Zhang, Hao Guo, Xiaoli Yang, Dandan Zhang, Di Zhang, Qiang Li, Chen Wang, Xuena Yang, Yongmin Xiong

Cartilage. 2021 Dec; 13(1 Suppl): 797S–808S. Published online 2021 Jan 16. doi: 10.1177/1947603520988165

PMCID:: PMC8808858

Abstract Article PDF–4.2M

Select item 86935027.

Assessment of children in the autistic spectrum disorder that carry the Thr92Ala-DIO2 polymorphism

A. A. e Marcondes, T. G. B. Gomez, T. T. Ravache, A. Batistuzzo, F. B. Lorena, C. S. de Paula, R. Lowenthal, A. C. Bianco, M. O. Ribeiro

J Endocrinol Invest. Author manuscript; available in PMC 2021 Dec 22.

Published in final edited form as: J Endocrinol Invest. 2021 Aug; 44(8): 1775–1782. Published online 2021 Jan 15. doi: 10.1007/s40618-020-01497-x

PMCID:: PMC8693502

Abstract Article PDF–383K

Select item 85165258.

The Type 2 Deiodinase Thr92Ala Polymorphism Is Associated with Higher Body Mass Index and Fasting Glucose Levels: A Systematic Review and Meta-Analysis

Xichang Wang, Kan Chen, Chenyu Zhang, Haoyu Wang, Jiashu Li, Chuyuan Wang, Weiping Teng, Zhongyan Shan, Yaxin Lai

Biomed Res Int. 2021; 2021: 9914009. Published online 2021 Oct 7. doi: 10.1155/2021/9914009

PMCID:: PMC8516525

Abstract Article PDF–520K

Select item 82379949.

Deiodinases and the Metabolic Code for Thyroid Hormone Action

Samuel C Russo, Federico Salas-Lucia, Antonio C Bianco

Endocrinology. 2021 Aug; 162(8): bqab059. Published online 2021 Mar 15. doi: 10.1210/endocr/bqab059

PMCID:: PMC8237994

Abstract Article

Select item 768548210.

High levels of maternal total tri-iodothyronine, and low levels of fetal free L-thyroxine and total tri-iodothyronine, are associated with altered deiodinase expression and activity in placenta with gestational diabetes mellitus

Sebastián Gutiérrez-Vega, Axel Armella, Daniela Mennickent, Marco Loyola, Ambart Covarrubias, Bernel Ortega-Contreras, Carlos Escudero, Marcelo Gonzalez, Martín Alcalá, María del Pilar Ramos, Marta Viana, Erica Castro, Andrea Leiva, Enrique Guzmán-Gutiérrez

PLoS One. 2020; 15(11): e0242743. Published online 2020 Nov 24. doi: 10.1371/journal.pone.0242743

PMCID:: PMC7685482

Abstract Article PDF–1.4M

Select item 683185111.

Rewiring of the Human Mitochondrial Interactome during Neuronal Reprogramming Reveals Regulators of the Respirasome and Neurogenesis

Mohamed Taha Moutaoufik, Ramy Malty, Shahreen Amin, Qingzhou Zhang, Sadhna Phanse, Alla Gagarinova, Mara Zilocchi, Larissa Hoell, Zoran Minic, Maria Gagarinova, Hiroyuki Aoki, Jocelyn Stockwell, Matthew Jessulat, Florian Goebels, Kirsten Broderick, Nichollas E. Scott, James Vlasblom, Gabriel Musso, Bhanu Prasad, Eleonora Lamantea, Barbara Garavaglia, Alex Rajput, Kei Murayama, Yasushi Okazaki, Leonard J. Foster, Gary D. Bader, Francisco S. Cayabyab, Mohan Babu

iScience. 2019 Sep 27; 19: 1114–1132. Published online 2019 Sep 4. doi: 10.1016/j.isci.2019.08.057

PMCID:: PMC6831851

Abstract Article PDF–9.8M

Select item 657102312.

Pathophysiological relevance of deiodinase polymorphism

Antonio C. Bianco, Brian S. Kim

Curr Opin Endocrinol Diabetes Obes. Author manuscript; available in PMC 2019 Jun 15.

Published in final edited form as: Curr Opin Endocrinol Diabetes Obes. 2018 Oct; 25(5): 341–346. doi: 10.1097/MED.0000000000000428

PMCID:: PMC6571023

Abstract Article PDF–305K

Select item 627671013.

A Common DIO2 Polymorphism and Alzheimer Disease Dementia in African and European Americans

Elizabeth A McAninch, Kumar B Rajan, Denis A Evans, Sungro Jo, Layal Chaker, Robin P Peeters, David A Bennett, Deborah C Mash, Antonio C Bianco

J Clin Endocrinol Metab. 2018 May; 103(5): 1818–1826. Published online 2018 Feb 22. doi: 10.1210/jc.2017-01196

PMCID:: PMC6276710

Abstract Article

Select item 607944014.

Adipocyte DIO2 Expression Increases in Human Obesity but Is Not Related to Systemic Insulin Sensitivity

David Bradley, Joey Liu, Alecia Blaszczak, Valerie Wright, Anahita Jalilvand, Bradley Needleman, Sabrena Noria, David Renton, Willa Hsueh

J Diabetes Res. 2018; 2018: 2464652. Published online 2018 Jul 15. doi: 10.1155/2018/2464652

PMCID:: PMC6079440

Abstract Article PDF–759K

Select item 603162215.

Concurrent TSHR mutations and DIO2 T92A polymorphism result in abnormal thyroid hormone metabolism

Eunkuk Park, Jaehoon Jung, Osamu Araki, Katsuhiko Tsunekawa, So Young Park, Jeonghyun Kim, Masami Murakami, Seon-Yong Jeong, Sihoon Lee

Sci Rep. 2018; 8: 10090. Published online 2018 Jul 4. doi: 10.1038/s41598-018-28480-0

PMCID:: PMC6031622

Abstract Article PDF–2.0M

Select item 567858116.

RNA-binding activity of TRIM25 is mediated by its PRY/SPRY domain and is required for ubiquitination

Nila Roy Choudhury, Gregory Heikel, Maryia Trubitsyna, Peter Kubik, Jakub Stanislaw Nowak, Shaun Webb, Sander Granneman, Christos Spanos, Juri Rappsilber, Alfredo Castello, Gracjan Michlewski

BMC Biol. 2017; 15: 105. Published online 2017 Nov 8. doi: 10.1186/s12915-017-0444-9

PMCID:: PMC5678581

Abstract Article PDF–3.2M

Select item 506195017.

The Type 2 Deiodinase Thr92Ala Polymorphism Is Associated with Worse Glycemic Control in Patients with Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis

Xiaowen Zhang, Jie Sun, Wenqing Han, Yaqiu Jiang, Shiqiao Peng, Zhongyan Shan, Weiping Teng

J Diabetes Res. 2016; 2016: 5928726. Published online 2016 Sep 29. doi: 10.1155/2016/5928726

PMCID:: PMC5061950

Abstract Article PDF–682K

Select item 492119318.

Effect of functionally significant deiodinase single nucleotide polymorphisms on drinking behavior in alcohol dependence: an exploratory investigation

MR Lee, ML Schwandt, JW Bollinger, AA Dias, EN Oot, D Goldman, CA Hodgkinson, L Leggio

Alcohol Clin Exp Res. Author manuscript; available in PMC 2016 Sep 1.

Published in final edited form as: Alcohol Clin Exp Res. 2015 Sep; 39(9): 1665–1670. Published online 2015 Jul 24. doi: 10.1111/acer.12814

PMCID:: PMC4921193

Abstract Article PDF–364K

Select item 460675519.

Type 2 Iodothyronine Deiodinase Activity Is Required for Rapid Stimulation of PI3K by Thyroxine in Human Umbilical Vein Endothelial Cells

Tomoyuki Aoki, Katsuhiko Tsunekawa, Osamu Araki, Takayuki Ogiwara, Makoto Nara, Hiroyuki Sumino, Takao Kimura, Masami Murakami

Endocrinology. 2015 Nov; 156(11): 4312–4324. Published online 2015 Aug 18. doi: 10.1210/en.2014-1988

PMCID:: PMC4606755

Abstract Article

Select item 451600020.

Underlying molecular mechanisms of DIO2 susceptibility in symptomatic osteoarthritis

Nils Bomer, Wouter den Hollander, Yolande F M Ramos, Steffan D Bos, Ruud van der Breggen, Nico Lakenberg, Barry A Pepers, Annelies E van Eeden, Arash Darvishan, Elmar W Tobi, Bouke J Duijnisveld, Erik B van den Akker, Bastiaan T Heijmans, Willeke MC van Roon-Mom, Fons J Verbeek, Gerjo J V M van Osch, Rob G H H Nelissen, P Eline Slagboom, Ingrid Meulenbelt

Ann Rheum Dis. 2015 Aug; 74(8): 1571–1579. Published online 2014 Apr 2. doi: 10.1136/annrheumdis-2013-204739

PMCID:: PMC4516000

Abstract Article PDF–3.0M

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