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Select item 109044931.

Skeletal muscle TET3 promotes insulin resistance through destabilisation of PGC-1α

Beibei Liu, Di Xie, Xinmei Huang, Sungho Jin, Yangyang Dai, Xiaoli Sun, Da Li, Anton M. Bennett, Sabrina Diano, Yingqun Huang

Diabetologia. 2024; 67(4): 724–737. Published online 2024 Jan 13. doi: 10.1007/s00125-023-06073-5

PMCID:: PMC10904493

Abstract Article PDF–1.4M

Select item 104998212.

Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets

Filip Mihalič, Caroline Benz, Eszter Kassa, Richard Lindqvist, Leandro Simonetti, Raviteja Inturi, Hanna Aronsson, Eva Andersson, Celestine N. Chi, Norman E. Davey, Anna K. Överby, Per Jemth, Ylva Ivarsson

Nat Commun. 2023; 14: 5636. Published online 2023 Sep 13. doi: 10.1038/s41467-023-41312-8

PMCID:: PMC10499821

Abstract Article PDF–2.6M

Select item 97058353.

Overexpression of Long Non-Coding RNA MIR22HG Represses Proliferation and Enhances Apoptosis via miR-629-5p/TET3 Axis in Osteosarcoma Cells

Haoliang Zhao, Ming Zhang, Xuejing Yang, Dong Song

J Microbiol Biotechnol. 2021 Oct 28; 31(10): 1331–1342. Published online 2021 Aug 9. doi: 10.4014/jmb.2106.06028

PMCID:: PMC9705835

Abstract Article PDF–4.9M

Select item 95251194.

TET3 epigenetically controls feeding and stress response behaviors via AGRP neurons

Di Xie, Bernardo Stutz, Feng Li, Fan Chen, Haining Lv, Matija Sestan-Pesa, Jonatas Catarino, Jianlei Gu, Hongyu Zhao, Christopher E. Stoddard, Gordon G. Carmichael, Marya Shanabrough, Hugh S. Taylor, Zhong-Wu Liu, Xiao-Bing Gao, Tamas L. Horvath, Yingqun Huang

J Clin Invest. 2022 Oct 3; 132(19): e162365. Published online 2022 Oct 3. doi: 10.1172/JCI162365

PMCID:: PMC9525119

Abstract Article PDF–3.3M

Select item 91197365.

OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization

Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti

Science. Author manuscript; available in PMC 2022 Sep 11.

Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983

PMCID:: PMC9119736

Abstract Article PDF–3.3M

Select item 87086916.

TET3- and OGT-Dependent Expression of Genes Involved in Epithelial-Mesenchymal Transition in Endometrial Cancer

Piotr Ciesielski, Paweł Jóźwiak, Ewa Forma, Anna Krześlak

Int J Mol Sci. 2021 Dec; 22(24): 13239. Published online 2021 Dec 8. doi: 10.3390/ijms222413239

PMCID:: PMC8708691

Abstract Article PDF–2.2M

Select item 82538197.

Redirected nuclear glutamate dehydrogenase supplies Tet3 with α-ketoglutarate in neurons

Franziska R. Traube, Dilara Özdemir, Hanife Sahin, Constanze Scheel, Andrea F. Glück, Anna S. Geserich, Sabine Oganesian, Sarantos Kostidis, Katharina Iwan, René Rahimoff, Grazia Giorgio, Markus Müller, Fabio Spada, Martin Biel, Jürgen Cox, Martin Giera, Stylianos Michalakis, Thomas Carell

Nat Commun. 2021; 12: 4100. Published online 2021 Jul 2. doi: 10.1038/s41467-021-24353-9

PMCID:: PMC8253819

Abstract Article PDF–5.2M

Select item 81650308.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 79985509.

Glyphosate and AMPA Induce Alterations in Expression of Genes Involved in Chromatin Architecture in Human Peripheral Blood Mononuclear Cells (In Vitro)

Ewelina Woźniak, Edyta Reszka, Ewa Jabłońska, Jaromir Michałowicz, Bogumiła Huras, Bożena Bukowska

Int J Mol Sci. 2021 Mar; 22(6): 2966. Published online 2021 Mar 15. doi: 10.3390/ijms22062966

PMCID:: PMC7998550

Abstract Article PDF–1.0M

Select item 770531010.

TET is targeted for proteasomal degradation by the PHD-pVHL pathway to reduce DNA hydroxymethylation

Sijia Fan, Jing Wang, Guangqing Yu, Fangjing Rong, Dawei Zhang, Chenxi Xu, Juan Du, Zhi Li, Gang Ouyang, Wuhan Xiao

J Biol Chem. 2020 Nov 27; 295(48): 16299–16313. Published online 2020 Sep 22. doi: 10.1074/jbc.RA120.014538

PMCID:: PMC7705310

Abstract Article PDF–2.8M

Select item 706367811.

A Positive Feedback Loop of TET3 and TGF-β1 Promotes Liver Fibrosis

Yetao Xu, Xiaoli Sun, Ruling Zhang, Tiefeng Cao, Shi-Ying Cai, James L. Boyer, Xuchen Zhang, Da Li, Yingqun Huang

Cell Rep. Author manuscript; available in PMC 2020 Mar 10.

Published in final edited form as: Cell Rep. 2020 Feb 4; 30(5): 1310–1318.e5. doi: 10.1016/j.celrep.2019.12.092

PMCID:: PMC7063678

Abstract Article PDF–2.0M

Select item 706009812.

Integrin α6 signaling induces STAT3-TET3-mediated hydroxymethylation of genes critical for maintenance of glioma stem cells

Andreas Herrmann, Christoph Lahtz, Jieun Song, Maryam Aftabizadeh, Gregory A. Cherryholmes, Hong Xin, Tomasz Adamus, Heehyoung Lee, David Grunert, Brian Armstrong, Peiguo Chu, Christine Brown, Michael Lim, Stephen Forman, Hua Yu

Oncogene. Author manuscript; available in PMC 2020 Jun 9.

Published in final edited form as: Oncogene. 2020 Mar; 39(10): 2156–2169. Published online 2019 Dec 9. doi: 10.1038/s41388-019-1134-6

PMCID:: PMC7060098

Abstract Article PDF–2.6M

Select item 703561913.

Selective targeting of TET catalytic domain promotes somatic cell reprogramming

Anup Kumar Singh, Bo Zhao, Xiuhua Liu, Xin Wang, Hongzhi Li, Hanjun Qin, Xiwei Wu, Yuelong Ma, David Horne, Xiaochun Yu

Proc Natl Acad Sci U S A. 2020 Feb 18; 117(7): 3621–3626. Published online 2020 Feb 5. doi: 10.1073/pnas.1910702117

PMCID:: PMC7035619

Abstract Article PDF–1.2M

Select item 701097814.

Delineation of a Human Mendelian Disorder of the DNA Demethylation Machinery: TET3 Deficiency

David B. Beck, Ana Petracovici, Chongsheng He, Hannah W. Moore, Raymond J. Louie, Muhammad Ansar, Sofia Douzgou, Sivagamy Sithambaram, Trudie Cottrell, Regie Lyn P. Santos-Cortez, Eloise J. Prijoles, Renee Bend, Boris Keren, Cyril Mignot, Marie-Christine Nougues, Katrin Õunap, Tiia Reimand, Sander Pajusalu, Muhammad Zahid, Muhammad Arif Nadeem Saqib, Julien Buratti, Eleanor G. Seaby, Kirsty McWalter, Aida Telegrafi, Dustin Baldridge, Marwan Shinawi, Suzanne M. Leal, G. Bradley Schaefer, Roger E. Stevenson, Siddharth Banka, Roberto Bonasio, Jill A. Fahrner

Am J Hum Genet. 2020 Feb 6; 106(2): 234–245. Published online 2020 Jan 9. doi: 10.1016/j.ajhg.2019.12.007

PMCID:: PMC7010978

Abstract Article PDF–2.3M

Select item 699835815.

Epigenetic induction of tumor stemness via the lipopolysaccharide-TET3-HOXB2 signaling axis in esophageal squamous cell carcinoma

Fengkai Xu, Zhonghe Liu, Ronghua Liu, Chunlai Lu, Lin Wang, Wei Mao, Qiaoliang Zhu, Huankai Shou, Kunpeng Zhang, Yin Li, Yiwei Chu, Jie Gu, Di Ge

Cell Commun Signal. 2020; 18: 17. Published online 2020 Feb 3. doi: 10.1186/s12964-020-0510-8

PMCID:: PMC6998358

Abstract Article PDF–7.8M

Select item 695946116.

Identification and validation of mRNA 3′untranslated regions of DNMT3B and TET3 as novel competing endogenous RNAs of the tumor suppressor PTEN

Kenneth Anthony R. Roquid, Krizelle Mae M. Alcantara, Reynaldo L. Garcia

Int J Oncol. 2020 Feb; 56(2): 544–558. Published online 2019 Dec 20. doi: 10.3892/ijo.2019.4947

PMCID:: PMC6959461

Abstract Article PDF–1.5M

Select item 681617117.

Increased expression of TET3 predicts unfavorable prognosis in patients with ovarian cancer-a bioinformatics integrative analysis

Tiefeng Cao, Wenwei Pan, Xiaoli Sun, Huimin Shen

J Ovarian Res. 2019; 12: 101. Published online 2019 Oct 27. doi: 10.1186/s13048-019-0575-4

PMCID:: PMC6816171

Abstract Article PDF–2.3M

Select item 677813718.

The midbody interactome reveals unexpected roles for PP1 phosphatases in cytokinesis

Luisa Capalbo, Zuni I. Bassi, Marco Geymonat, Sofia Todesca, Liviu Copoiu, Anton J. Enright, Giuliano Callaini, Maria Giovanna Riparbelli, Lu Yu, Jyoti S. Choudhary, Enrico Ferrero, Sally Wheatley, Max E. Douglas, Masanori Mishima, Pier Paolo D’Avino

Nat Commun. 2019; 10: 4513. Published online 2019 Oct 4. doi: 10.1038/s41467-019-12507-9

PMCID:: PMC6778137

Abstract Article PDF–7.8M

Select item 668252919.

Aberrant DNA methylation of synaptophysin is involved in adrenal cortisol-producing adenoma

Jia-Yu Zhong, Rong-Rong Cui, Xiao Lin, Feng Xu, Ting Zhu, Fuxingzi Li, Feng Wu, En Zhou, Lu Yi, Ling-Qing Yuan

Aging (Albany NY) 2019 Jul 31; 11(14): 5232–5245. Published online 2019 Jul 28. doi: 10.18632/aging.102119

PMCID:: PMC6682529

Abstract Article PDF–4.4M

Select item 646665120.

Hyperglycemia affects global 5-methylcytosine and 5-hydroxymethylcytosine in blood genomic DNA through upregulation of SIRT6 and TETs

Er-Feng Yuan, Ying Yang, Lin Cheng, Xujing Deng, Shao-Min Chen, Xin Zhou, Song-Mei Liu

Clin Epigenetics. 2019; 11: 63. Published online 2019 Apr 15. doi: 10.1186/s13148-019-0660-y

PMCID:: PMC6466651

Abstract Article PDF–1.0M

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