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Items: 1 to 20 of 79

1.
Pulse-SILAC and Interactomics Reveal Distinct DDB1-CUL4–Associated Factors, Cellular Functions, and Protein Substrates
Jennifer Raisch, Marie-Line Dubois, Marika Groleau, Dominique Lévesque, Thomas Burger, Carla-Marie Jurkovic, Romain Brailly, Gwendoline Marbach, Alyson McKenna, Catherine Barrette, Pierre-Étienne Jacques, François-Michel Boisvert
Mol Cell Proteomics. 2023 Oct; 22(10): 100644. Published online 2023 Sep 7. doi: 10.1016/j.mcpro.2023.100644
PMCID:
PMC10565876
AbstractArticlePDF–3.7M
2.
TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing
Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan
Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233
PMCID:
PMC10237422
AbstractArticlePDF–23M
3.
SARS-CoV-2 Nsp6 damages Drosophila heart and mouse cardiomyocytes through MGA/MAX complex-mediated increased glycolysis
Jun-yi Zhu, Guanglei Wang, Xiaohu Huang, Hangnoh Lee, Jin-Gu Lee, Penghua Yang, Joyce van de Leemput, Weiliang Huang, Maureen A. Kane, Peixin Yang, Zhe Han
Commun Biol. 2022; 5: 1039. Published online 2022 Sep 30. doi: 10.1038/s42003-022-03986-6
PMCID:
PMC9523645
AbstractArticlePDF–3.9M
4.
TRIM22 orchestrates the proliferation of GBMs and the benefits of TMZ by coordinating the modification and degradation of RIG-I
Xiaowei Fei, Xiuquan Wu, Ya-Nan Dou, Kai Sun, Qingdong Guo, Lei Zhang, Sanzhong Li, Jialiang Wei, Yu Huan, Xin He, Zhou Fei
Mol Ther Oncolytics. 2022 Sep 15; 26: 413–428. Published online 2022 Aug 25. doi: 10.1016/j.omto.2022.08.007
PMCID:
PMC9465028
AbstractArticlePDF–7.2M
5.
Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery
Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili
Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z
PMCID:
PMC9279285
AbstractArticlePDF–2.5M
6.
The involvement of Parkin-dependent mitophagy in the anti-cancer activity of Ginsenoside
Xin Sun, Yeting Hong, Yuhan Shu, Caixia Wu, Guiqin Ye, Hanxiao Chen, Hongying Zhou, Ruilan Gao, Jianbin Zhang
J Ginseng Res. 2022 Mar; 46(2): 266–274. Published online 2021 Jul 8. doi: 10.1016/j.jgr.2021.06.009
PMCID:
PMC9058836
AbstractArticlePDF–2.9M
7.
Associations between Gene-Gene Interaction and Overweight/Obesity of 12-Month-Old Chinese Infants
Hong Mei, Baoming Yin, Wenhong Yang, Jingli Zhang, Hongyan Lu, Xiaobin Qi, Wenhua Mei, Hongzhong Zhang, Jianduan Zhang
Biomed Res Int. 2022; 2022: 1499454. Published online 2022 Mar 7. doi: 10.1155/2022/1499454
PMCID:
PMC8920651
AbstractArticlePDF–470K
8.
Histone deacetylase inhibitors inhibit cervical cancer growth through Parkin acetylation-mediated mitophagy
Xin Sun, Yuhan Shu, Guiqin Ye, Caixia Wu, Mengting Xu, Ruilan Gao, Dongsheng Huang, Jianbin Zhang
Acta Pharm Sin B. 2022 Feb; 12(2): 838–852. Published online 2021 Jul 21. doi: 10.1016/j.apsb.2021.07.003
PMCID:
PMC8897022
AbstractArticlePDF–3.0M
9.
Tau interactome maps synaptic and mitochondrial processes associated with neurodegeneration
Tara E. Tracy, Jesus Madero-Pérez, Danielle L. Swaney, Timothy S. Chang, Michelle Moritz, Csaba Konrad, Michael E. Ward, Erica Stevenson, Ruth Hüttenhain, Grant Kauwe, Maria Mercedes, Lauren Sweetland-Martin, Xu Chen, Sue-Ann Mok, Man Ying Wong, Maria Telpoukhovskaia, Sang-Won Min, Chao Wang, Peter Dongmin Sohn, Jordie Martin, Yungui Zhou, Wenjie Luo, John Q. Trojanowski, Virginia M.Y. Lee, Shiaoching Gong, Giovanni Manfredi, Giovanni Coppola, Nevan J. Krogan, Daniel H. Geschwind, Li Gan
Cell. Author manuscript; available in PMC 2022 Feb 19.
Published in final edited form as: Cell. 2022 Feb 17; 185(4): 712–728.e14. Published online 2022 Jan 20. doi: 10.1016/j.cell.2021.12.041
PMCID:
PMC8857049
AbstractArticlePDF–3.6M
10.
Human transcription factor protein interaction networks
Helka Göös, Matias Kinnunen, Kari Salokas, Zenglai Tan, Xiaonan Liu, Leena Yadav, Qin Zhang, Gong-Hong Wei, Markku Varjosalo
Nat Commun. 2022; 13: 766. Published online 2022 Feb 9. doi: 10.1038/s41467-022-28341-5
PMCID:
PMC8828895
AbstractArticlePDF–1.7M
11.
NUDT15 polymorphism and NT5C2 and PRPS1 mutations influence thiopurine sensitivity in acute lymphoblastic leukaemia cells
Shinpei Somazu, Yoichi Tanaka, Minori Tamai, Atsushi Watanabe, Keiko Kagami, Masako Abe, Daisuke Harama, Tamao Shinohara, Koshi Akahane, Kumiko Goi, Kanji Sugita, Takaya Moriyama, Jun Yang, Hiroaki Goto, Masayoshi Minegishi, Shotaro Iwamoto, Junko Takita, Takeshi Inukai
J Cell Mol Med. 2021 Nov; 25(22): 10521–10533. Published online 2021 Oct 12. doi: 10.1111/jcmm.16981
PMCID:
PMC8581340
AbstractArticlePDF–1.5M
12.
SNX27-driven membrane localisation of OTULIN antagonises linear ubiquitination and NF-κB signalling activation
Ruona Shi, Xue Shi, Dajiang Qin, Shibing Tang, Michiel Vermeulen, Xiaofei Zhang
Cell Biosci. 2021; 11: 146. Published online 2021 Jul 27. doi: 10.1186/s13578-021-00659-5
PMCID:
PMC8314547
AbstractArticlePDF–3.7M
13.
Cytosolic 5′-Nucleotidase II Silencing in Lung Tumor Cells Regulates Metabolism through Activation of the p53/AMPK Signaling Pathway
Rossana Pesi, Simone Allegrini, Mercedes Garcia-Gil, Lucia Piazza, Roberta Moschini, Lars Petter Jordheim, Marcella Camici, Maria Grazia Tozzi
Int J Mol Sci. 2021 Jul; 22(13): 7004. Published online 2021 Jun 29. doi: 10.3390/ijms22137004
PMCID:
PMC8268954
AbstractArticlePDF–3.0M
14.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
15.
Effects of NT5C2 germline variants on 6-mecaptopurine metabolism in children with acute lymphoblastic leukemia
Chuang Jiang, Wenjian Yang, Takaya Moriyama, Chengcheng Liu, Colton Smith, Wentao Yang, Maoxiang Qian, Ziping Li, Morten Tulstrup, Kjeld Schmiegelow, Kristine R. Crews, Hui Zhang, Ching-Hon Pui, William Evans, Mary Relling, Smita Bhatia, Jun J. YangP
Clin Pharmacol Ther. Author manuscript; available in PMC 2022 Jun 1.
Published in final edited form as: Clin Pharmacol Ther. 2021 Jun; 109(6): 1538–1545. Published online 2020 Nov 24. doi: 10.1002/cpt.2095
PMCID:
PMC8081740
AbstractArticlePDF–716K
16.
Characterization of SARS-CoV-2 proteins reveals Orf6 pathogenicity, subcellular localization, host interactions and attenuation by Selinexor
Jin-Gu Lee, Weiliang Huang, Hangnoh Lee, Joyce van de Leemput, Maureen A. Kane, Zhe Han
Cell Biosci. 2021; 11: 58. Published online 2021 Mar 25. doi: 10.1186/s13578-021-00568-7
PMCID:
PMC7993076
AbstractArticlePDF–2.0M
17.
GREB1: An evolutionarily conserved protein with a glycosyltransferase domain links ERα glycosylation and stability to cancer
Eun Myoung Shin, Vinh Thang Huynh, Sultan Abda Neja, Chia Yi Liu, Anandhkumar Raju, Kelly Tan, Nguan Soon Tan, Jayantha Gunaratne, Xuezhi Bi, Lakshminarayan M. Iyer, L. Aravind, Vinay Tergaonkar
Sci Adv. 2021 Mar; 7(12): eabe2470. Published online 2021 Mar 17. doi: 10.1126/sciadv.abe2470
PMCID:
PMC7968844
AbstractArticlePDF–1.1M
18.
Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism
Michael Aregger, Keith A. Lawson, Maximillian Billmann, Michael Costanzo, Amy H. Y. Tong, Katherine Chan, Mahfuzur Rahman, Kevin R. Brown, Catherine Ross, Matej Usaj, Lucy Nedyalkova, Olga Sizova, Andrea Habsid, Judy Pawling, Zhen-Yuan Lin, Hala Abdouni, Cassandra J. Wong, Alexander Weiss, Patricia Mero, James W. Dennis, Anne-Claude Gingras, Chad L. Myers, Brenda J. Andrews, Charles Boone, Jason Moffat
Nat Metab. Author manuscript; available in PMC 2020 Dec 1.
Published in final edited form as: Nat Metab. 2020 Jun; 2(6): 499–513. Published online 2020 Jun 1. doi: 10.1038/s42255-020-0211-z
PMCID:
PMC7566881
AbstractArticlePDF–4.8M
19.
NT5C2 methylation regulatory interplay between DNMT1 and insulin receptor in type 2 diabetes
Yng-Tay Chen, Wei-De Lin, Wen-Ling Liao, Ya-Ching Tsai, Jiunn-Wang Liao, Fuu-Jen Tsai
Sci Rep. 2020; 10: 16087. Published online 2020 Sep 30. doi: 10.1038/s41598-020-71336-9
Correction in:
Sci Rep. 2021; 11: 6961.
PMCID:
PMC7527562
AbstractArticlePDF–1.6M
20.
Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis
Katrin Tiemann, Carolina Garri, Sang Bok Lee, Paymaneh D. Malihi, Mincheol Park, Ruth M. Alvarez, Li Peng Yap, Parag Mallick, Jonathan E. Katz, Mitchell E. Gross, Kian Kani
Oncogene. Author manuscript; available in PMC 2020 Sep 29.
Published in final edited form as: Oncogene. 2019 Apr; 38(16): 3003–3018. Published online 2018 Dec 21. doi: 10.1038/s41388-018-0638-9
PMCID:
PMC7523706
AbstractArticlePDF–2.3M

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