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Items: 1 to 20 of 221

1.
NEDD4L is a promoter for angiogenesis and cell proliferation in human umbilical vein endothelial cells
Binghong Liu, Fei Song, Xiaoxia Zhou, Chan Wu, Huizhu Huang, Weiyin Wu, Gang Li, Yan Wang
J Cell Mol Med. 2024 Apr; 28(8): 1–11. Published online 2024 Mar 25. doi: 10.1111/jcmm.18233
PMCID:
PMC10962128
AbstractArticlePDF–17M
2.
NEDD4L intramolecular interactions regulate its auto and substrate NaV1.5 ubiquitination
Katharine M. Wright, Sara Nathan, Hanjie Jiang, Wendy Xia, HyoJeon Kim, Nourdine Chakouri, Justin N. Nwafor, Lucile Fossier, Lakshmi Srinivasan, Zan Chen, Tatiana Boronina, Jeremy Post, Suman Paul, Robert N. Cole, Manu Ben-Johny, Philip A. Cole, Sandra B. Gabelli
J Biol Chem. 2024 Mar; 300(3): 105715. Published online 2024 Feb 2. doi: 10.1016/j.jbc.2024.105715
PMCID:
PMC10933555
AbstractArticlePDF–5.1M
3.
METTL3 regulates TFRC ubiquitination and ferroptosis through stabilizing NEDD4L mRNA to impact stroke
Wenjie Su, Xiang Yu, Shan Wang, Xu Wang, Zheng Dai, Yi Li
Cell Biol Toxicol. 2024; 40(1): 8. Published online 2024 Feb 2. doi: 10.1007/s10565-024-09844-x
PMCID:
PMC10834616
AbstractArticlePDF–7.0M
4.
The RNA-binding protein KSRP aggravates malignant progression of clear cell renal cell carcinoma through transcriptional inhibition and post-transcriptional destabilization of the NEDD4L ubiquitin ligase
Yi-Chieh Yang, Yung-Wei Lin, Wei-Jiunn Lee, Feng-Ru Lai, Kuo-Hao Ho, Chih-Ying Chu, Kuo-Tai Hua, Ji-Qing Chen, Min-Che Tung, Michael Hsiao, Yu-Ching Wen, Ming-Hsien Chien
J Biomed Sci. 2023; 30: 68. Published online 2023 Aug 14. doi: 10.1186/s12929-023-00949-9
PMCID:
PMC10424398
AbstractArticlePDF–6.4M
5.
Genetic analysis of periventricular nodular heterotopia 7 caused by a novel NEDD4L missense mutation: Case and literature summary
Juan Liu, Jihong Hu, Yaqing Duan, Rong Qin, Chunguang Guo, Hongtao Zhou, Hua Liu, Chunlei Liu
Mol Genet Genomic Med. 2023 Jul; 11(7): e2169. Published online 2023 Mar 19. doi: 10.1002/mgg3.2169
PMCID:
PMC10337284
AbstractArticlePDF–1.8M
6.
TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing
Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan
Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233
PMCID:
PMC10237422
AbstractArticlePDF–23M
7.
Cytoplasmic YAP1‐mediated ESCRT‐III assembly promotes autophagic cell death and is ubiquitinated by NEDD4L in breast cancer
Yan Guo, Yuqing Cui, Yangyang Li, Xiaoying Jin, Dandan Wang, Mengxia Lei, Fengzhi Chen, Yali Liu, Jinwen Xu, Guanyu Yao, Guangchun Zeng, Xuesong Chen
Cancer Commun (Lond) 2023 May; 43(5): 582–612. Published online 2023 Apr 2. doi: 10.1002/cac2.12417
PMCID:
PMC10174091
AbstractArticlePDF–22M
8.
Nedd4L suppression in lung fibroblasts facilitates pathogenesis of lung fibrosis
Shuang Li, Qinmao Ye, Jianxin Wei, Sarah J Taleb, Heather Wang, Yingze Zhang, Daniel J Kass, Jeffrey C Horowitz, Jing Zhao, Yutong Zhao
Transl Res. Author manuscript; available in PMC 2023 May 9.
Published in final edited form as: Transl Res. 2023 Mar; 253: 1–7. Published online 2022 Oct 17. doi: 10.1016/j.trsl.2022.10.002
PMCID:
PMC10167741
AbstractArticlePDF–1.4M
9.
NEDD4L facilitates granulosa cell ferroptosis by promoting GPX4 ubiquitination and degradation
Hong Tang, Xiaomei Jiang, Yu Hua, Heyue Li, Chunlan Zhu, Xiaobai Hao, Minhui Yi, Linxia Li
Endocr Connect. 2023 Apr 1; 12(4): e220459. Prepublished online 2023 Jan 20. Published online 2023 Mar 17. doi: 10.1530/EC-22-0459
PMCID:
PMC10083675
AbstractArticlePDF–2.2M
10.
AMPK phosphorylates and stabilises copper transporter 1 to synergise metformin and copper chelator for breast cancer therapy
Xiaomei Zhang, Qiwei Jiang, Yaqing Su, Lang Bu, Zicheng Sun, Xueji Wu, Bing Gao, Lei Wang, Ying Lin, Wei Xie, Jianping Guo
Br J Cancer. 2023 Apr 12; 128(8): 1452–1465. Published online 2023 Feb 17. doi: 10.1038/s41416-022-02127-4
PMCID:
PMC10070418
AbstractArticlePDF–2.8M
11.
circNEIL3 inhibits tumor metastasis through recruiting the E3 ubiquitin ligase Nedd4L to degrade YBX1
Shuang Chen, Ke Li, Jiawei Guo, Hai-Ning Chen, Yue Ming, Yang Jin, Fuyan Xu, Tingting Zhang, Yang Yang, Zixia Ye, Wenrong Liu, Hulin Ma, Jian Cheng, Jian-Kang Zhou, Zhang Li, Shu Shen, Lunzhi Dai, Zong-Guang Zhou, Heng Xu, Yong Peng
Proc Natl Acad Sci U S A. 2023 Mar 28; 120(13): e2215132120. Published online 2023 Mar 24. doi: 10.1073/pnas.2215132120
PMCID:
PMC10068820
AbstractArticlePDF–3.9M
12.
Fibril treatment changes protein interactions of tau and α-synuclein in human neurons
Tagan A. Griffin, Paul D. Schnier, Elisa M. Cleveland, Robert W. Newberry, Julia Becker, George A. Carlson
J Biol Chem. 2023 Mar; 299(3): 102888. Published online 2023 Jan 10. doi: 10.1016/j.jbc.2023.102888
PMCID:
PMC9978635
AbstractArticlePDF–10M
13.
NEDD4L inhibits cell viability, cell cycle progression, and glutamine metabolism in esophageal squamous cell carcinoma via ubiquitination of c-Myc: NEDD4L and c-Myc coordinate to regulate ESCC
Wei Cheng, Guiyuan Li, Zhou Ye, Jun Hu, Lixia Gao, Xiaoling Jia, Suping Zhao, Yan Wang, Qin Zhou
Acta Biochim Biophys Sin (Shanghai) 2022 May; 54(5): 716–724. Published online 2022 May 16. doi: 10.3724/abbs.2022048
PMCID:
PMC9827801
AbstractArticlePDF–9.1M
14.
Paeoniflorin Regulates NEDD4L/STAT3 Pathway to Induce Ferroptosis in Human Glioma Cells
Xiao-Hu Nie, Sheng Qiu, Ying Xing, Jie Xu, Bin Lu, Shu-Fa Zhao, Yun-Tao Li, Zhong-Zhou Su
J Oncol. 2022; 2022: 6093216. Published online 2022 Dec 28. doi: 10.1155/2022/6093216
PMCID:
PMC9812627
AbstractArticlePDF–1.9M
15.
(Pro)renin receptor promotes colorectal cancer progression through inhibiting the NEDD4L-mediated Wnt3 ubiquitination and modulating gut microbiota
Juan Wang, Yuwei Ding, Dan Li, Ning Zhu, Akira Nishiyama, Ying Yuan
Cell Commun Signal. 2023; 21: 2. Published online 2023 Jan 3. doi: 10.1186/s12964-022-01015-x
PMCID:
PMC9809055
AbstractArticlePDF–2.7M
16.
HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation
Jingsheng Yuan, Tao Lv, Jian Yang, Zhenru Wu, Lvnan Yan, Jiayin Yang, Yujun Shi, Li Jiang
Cell Mol Gastroenterol Hepatol. 2023; 15(2): 307–325. Published online 2022 Oct 14. doi: 10.1016/j.jcmgh.2022.10.005
PMCID:
PMC9772558
AbstractArticlePDF–8.2M
17.
E3 ubiquitin ligase NEDD4L negatively regulates inflammation by promoting ubiquitination of MEKK2
Hui Li, Ning Wang, Yu Jiang, Haofei Wang, Zengfeng Xin, Huazhang An, Hao Pan, Wangqian Ma, Ting Zhang, Xiaojian Wang, Wenlong Lin
EMBO Rep. 2022 Nov; 23(11): e54603. Published online 2022 Sep 26. doi: 10.15252/embr.202254603
PMCID:
PMC9638856
AbstractArticlePDF–4.2M
18.
Hypoxic glioma‐derived extracellular vesicles harboring MicroRNA‐10b‐5p enhance M2 polarization of macrophages to promote the development of glioma
Bingzhen Li, Cheng Yang, Zhanpeng Zhu, Hao Chen, Bin Qi
CNS Neurosci Ther. 2022 Nov; 28(11): 1733–1747. Published online 2022 Sep 2. doi: 10.1111/cns.13905
PMCID:
PMC9532931
AbstractArticlePDF–6.5M
19.
ALS-linked loss of Cyclin-F function affects HSP90
Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends
Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359
PMCID:
PMC9481933
AbstractArticlePDF–3.5M
20.
LINC00941 promotes pancreatic cancer malignancy by interacting with ANXA2 and suppressing NEDD4L-mediated degradation of ANXA2
Jie Wang, Zhiwei He, Xinyuan Liu, Jian Xu, Xueyi Jiang, Gang Quan, Jianxin Jiang
Cell Death Dis. 2022 Aug; 13(8): 718. Published online 2022 Aug 18. doi: 10.1038/s41419-022-05172-2
PMCID:
PMC9385862
AbstractArticlePDF–6.6M

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