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Select item 109176601.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 107613242.

Dynamic encounters with red blood cells trigger splenic marginal zone B cell retention and function

Dan Liu, Benjamin Y. Winer, Marissa Y. Chou, Hanson Tam, Ying Xu, Jinping An, James M. Gardner, Jason G. Cyster

Nat Immunol. 2024; 25(1): 142–154. Published online 2023 Dec 4. doi: 10.1038/s41590-023-01690-z

PMCID:: PMC10761324

Abstract Article PDF–11M

Select item 99382163.

Rescue of neuropsychiatric phenotypes in a mouse model of 16p11.2 duplication syndrome by genetic correction of an epilepsy network hub

Marc P. Forrest, Marc Dos Santos, Nicolas H. Piguel, Yi-Zhi Wang, Nicole A. Hawkins, Vikram A. Bagchi, Leonardo E. Dionisio, Sehyoun Yoon, Dina Simkin, Maria Dolores Martin-de-Saavedra, Ruoqi Gao, Katherine E. Horan, Alfred L. George, Jr., Mark S. LeDoux, Jennifer A. Kearney, Jeffrey N. Savas, Peter Penzes

Nat Commun. 2023; 14: 825. Published online 2023 Feb 17. doi: 10.1038/s41467-023-36087-x

PMCID:: PMC9938216

Abstract Article PDF–5.3M

Select item 94819334.

ALS-linked loss of Cyclin-F function affects HSP90

Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends

Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359

PMCID:: PMC9481933

Abstract Article PDF–3.5M

Select item 93100865.

CD97 promotes spleen dendritic cell homeostasis through the mechanosensing of red blood cells

Dan Liu, Lihui Duan, Lauren B Rodda, Erick Lu, Ying Xu, Jinping An, Longhui Qiu, Fengchun Liu, Mark R Looney, Zhiyong Yang, Christopher D C Allen, Zhongmei Li, Alexander Marson, Jason G Cyster

Science. Author manuscript; available in PMC 2023 Feb 11.

Published in final edited form as: Science. 2022 Feb 11; 375(6581): eabi5965. Published online 2022 Feb 11. doi: 10.1126/science.abi5965

PMCID:: PMC9310086

Abstract Article PDF–2.9M

Select item 89896266.

Gα13 loss in Kras/Tp53 mouse model of pancreatic tumorigenesis promotes tumors susceptible to rapamycin

Mario A. Shields, Christina Spaulding, Anastasia E. Metropulos, Mahmoud G. Khalafalla, Thao N.D. Pharm, Hidayatullah G. Munshi

Cell Rep. Author manuscript; available in PMC 2022 Apr 8.

Published in final edited form as: Cell Rep. 2022 Mar 1; 38(9): 110441. doi: 10.1016/j.celrep.2022.110441

PMCID:: PMC8989626

Abstract Article PDF–2.2M

Select item 81599677.

Targeting Gα₁₃-integrin interaction ameliorates systemic inflammation

Ni Cheng, Yaping Zhang, M. Keegan Delaney, Can Wang, Yanyan Bai, Randal A. Skidgel, Xiaoping Du

Nat Commun. 2021; 12: 3185. Published online 2021 May 27. doi: 10.1038/s41467-021-23409-0

PMCID:: PMC8159967

Abstract Article PDF–2.6M

Select item 79387708.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 76945769.

Compromised counterselection by FAS creates an aggressive subtype of germinal center lymphoma

Raud Razzaghi, Shreya Agarwal, Nikita Kotlov, Olga Plotnikova, Krystle Nomie, Da Wei Huang, George W. Wright, Grace A. Smith, Moyi Li, Katsuyoshi Takata, Maryam Yamadi, Chen Yao, John J. O’Shea, James D. Phelan, Stefania Pittaluga, David W. Scott, Jagan R. Muppidi

J Exp Med. 2021 Mar 1; 218(3): e20201173. Published online 2020 Nov 25. doi: 10.1084/jem.20201173

PMCID:: PMC7694576

Abstract Article PDF–6.4M

Select item 726179510.

Knockout mouse models reveal the contributions of G protein subunits to complement C5a receptor–mediated chemotaxis

Esther van den Bos, Benjamin Ambrosy, Markus Horsthemke, Stefan Walbaum, Anne C. Bachg, Nina Wettschureck, Giulio Innamorati, Thomas M. Wilkie, Peter J. Hanley

J Biol Chem. 2020 May 29; 295(22): 7726–7742. Published online 2020 Apr 24. doi: 10.1074/jbc.RA119.011984

PMCID:: PMC7261795

Abstract Article PDF–5.0M

Select item 677797911.

Myogenic vasoconstriction requires G₁₂/G₁₃ and LARG to maintain local and systemic vascular resistance

Ramesh Chennupati, Angela Wirth, Julie Favre, Rui Li, Rémy Bonnavion, Young-June Jin, Astrid Wietelmann, Frank Schweda, Nina Wettschureck, Daniel Henrion, Stefan Offermanns

eLife. 2019; 8: e49374. Published online 2019 Sep 24. doi: 10.7554/eLife.49374

PMCID:: PMC6777979

Abstract Article PDF–4.6M

Select item 641460412.

G-protein Gα₁₃ functions as a cytoskeletal and mitochondrial regulator to restrain osteoclast function

Shinichi Nakano, Kazuki Inoue, Cheng Xu, Zhonghao Deng, Viktoriya Syrovatkina, Gregory Vitone, Liang Zhao, Xin-Yun Huang, Baohong Zhao

Sci Rep. 2019; 9: 4236. Published online 2019 Mar 12. doi: 10.1038/s41598-019-40974-z

PMCID:: PMC6414604

Abstract Article PDF–4.7M

Select item 624418313.

Complementary proteomics strategies capture an ataxin-1 interactome in Neuro-2a cells

Sunyuan Zhang, Nicholas A. Williamson, Marie A. Bogoyevitch

Sci Data. 2018; 5: 180262. Published online 2018 Nov 20. doi: 10.1038/sdata.2018.262

PMCID:: PMC6244183

Abstract Article PDF–753K

Select item 620547314.

Translating biased signaling in the ghrelin receptor system into differential in vivo functions

Franziska Mende, Cecilie Hundahl, Bianca Plouffe, Louise Julie Skov, Bjørn Sivertsen, Andreas Nygaard Madsen, Michael Lückmann, Thi Ai Diep, Stefan Offermanns, Thomas Michael Frimurer, Michel Bouvier, Birgitte Holst

Proc Natl Acad Sci U S A. 2018 Oct 23; 115(43): E10255–E10264. Published online 2018 Oct 9. doi: 10.1073/pnas.1804003115