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Select item 109176601.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 105339992.

p90RSK2, a new MLCK mediates contractility in myosin light chain kinase null smooth muscle

Jaspreet Kalra, Mykhaylo Artamonov, Hua Wang, Aaron Franke, Zaneta Markowska, Li Jin, Zygmunt S. Derewenda, Ramon J. Ayon, Avril Somlyo

Front Physiol. 2023; 14: 1228488. Published online 2023 Sep 13. doi: 10.3389/fphys.2023.1228488

PMCID:: PMC10533999

Abstract Article PDF–2.8M

Select item 101095193.

The RSK2-RPS6 axis promotes axonal regeneration in the peripheral and central nervous systems

Charlotte Decourt, Julia Schaeffer, Beatrice Blot, Antoine Paccard, Blandine Excoffier, Mario Pende, Homaira Nawabi, Stephane Belin

PLoS Biol. 2023 Apr; 21(4): e3002044. Published online 2023 Apr 17. doi: 10.1371/journal.pbio.3002044

PMCID:: PMC10109519

Abstract Article PDF–5.3M

Select item 86015104.

Osteoblast-specific inactivation of p53 results in locally increased bone formation

Nannan Liao, Till Koehne, Jan Tuckermann, Ioanna Triviai, Michael Amling, Jean-Pierre David, Thorsten Schinke, Julia Luther

PLoS One. 2021; 16(11): e0249894. Published online 2021 Nov 18. doi: 10.1371/journal.pone.0249894

PMCID:: PMC8601510

Abstract Article PDF–3.3M

Select item 83132395.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Abstract Article PDF–1.6M

Select item 74656946.

RSK2 Maintains Adult Estrogen Homeostasis by Inhibiting ERK1/2-Mediated Degradation of Estrogen Receptor Alpha

Katarzyna A. Ludwik, Zachary M. Sandusky, Kimberly M. Stauffer, Yu Li, Kelli L. Boyd, George A. O’Doherty, Thomas P. Stricker, Deborah A. Lannigan

Cell Rep. Author manuscript; available in PMC 2020 Sep 2.

Published in final edited form as: Cell Rep. 2020 Jul 21; 32(3): 107931. doi: 10.1016/j.celrep.2020.107931

PMCID:: PMC7465694

Abstract Article PDF–3.5M

Select item 74159917.

BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING)

Kou Motani, Hidetaka Kosako

J Biol Chem. 2020 Aug 7; 295(32): 11174–11183. Published online 2020 Jun 17. doi: 10.1074/jbc.RA120.014323

PMCID:: PMC7415991

Abstract Article PDF–2.0M

Select item 72950418.

RSK-3 promotes cartilage regeneration via interacting with rpS6 in cartilage stem/progenitor cells

Shuai Zhang, Md Rana Hamid, Ting Wang, Jinqi Liao, Liru Wen, Yan Zhou, Pengfei Wei, Xuenong Zou, Gang Chen, Junhui Chen, Guangqian Zhou

Theranostics. 2020; 10(15): 6915–6927. Published online 2020 May 25. doi: 10.7150/thno.44875

PMCID:: PMC7295041

Abstract Article PDF–3.6M

Select item 66187609.

The Coffin-Lowry Syndrome-Associated Protein RSK2 Regulates Neurite Outgrowth through Phosphorylation of Phospholipase D1 (PLD1) and Synthesis of Phosphatidic Acid

Mohamed-Raafet Ammar, Yann Humeau, André Hanauer, Bernard Nieswandt, Marie-France Bader, Nicolas Vitale

J Neurosci. 2013 Dec 11; 33(50): 19470–19479. doi: 10.1523/JNEUROSCI.2283-13.2013

PMCID:: PMC6618760

Abstract Article PDF–2.4M

Select item 647424610.

RSK2 contributes to myogenic vasoconstriction of resistance arteries by activating smooth muscle myosin and the Na⁺/H⁺ exchanger

Mykhaylo V. Artamonov, Swapnil K. Sonkusare, Miranda E. Good, Ko Momotani, Masumi Eto, Brant E. Isakson, Thu H. Le, Eric L. Cope, Zygmunt S. Derewenda, Urszula Derewenda, Avril V. Somlyo

Sci Signal. Author manuscript; available in PMC 2019 Apr 19.

Published in final edited form as: Sci Signal. 2018 Oct 30; 11(554): eaar3924. Published online 2018 Oct 30. doi: 10.1126/scisignal.aar3924

PMCID:: PMC6474246

Abstract Article PDF–1.7M

Select item 624418311.

Complementary proteomics strategies capture an ataxin-1 interactome in Neuro-2a cells

Sunyuan Zhang, Nicholas A. Williamson, Marie A. Bogoyevitch

Sci Data. 2018; 5: 180262. Published online 2018 Nov 20. doi: 10.1038/sdata.2018.262

PMCID:: PMC6244183

Abstract Article PDF–753K

Select item 602375312.

RSK2 is required for TRAF6 phosphorylation-mediated colon inflammation

Ke Yao, Sung-Young Lee, Cong Peng, Do Young Lim, Hiroyuki Yamamoto, Joohyun Ryu, Tae-Gyu Lim, Hanyong Chen, Guoguo Jin, Zhenjiang Zhao, Yaping Han, Wei-Ya Ma, Ann M. Bode, Zigang Dong

Oncogene. Author manuscript; available in PMC 2018 Sep 22.

Published in final edited form as: Oncogene. 2018 Jun; 37(26): 3501–3513. Published online 2018 Mar 22. doi: 10.1038/s41388-018-0167-6

PMCID:: PMC6023753

Abstract Article PDF–926K

Select item 588840113.

A ERK/RSK-mediated negative feedback loop regulates M-CSF–evoked PI3K/AKT activation in macrophages

Lijun Wang, Caterina Iorio, Kevin Yan, Howard Yang, Sunao Takeshita, Sumin Kang, Benjamin G. Neel, Wentian Yang

FASEB J. 2018 Feb; 32(2): 875–887. Published online 2017 Oct 18. doi: 10.1096/fj.201700672RR

PMCID:: PMC5888401

Abstract Article

Select item 581819514.

Differential control of Toll-like receptor 4–induced interleukin-10 induction in macrophages and B cells reveals a role for p90 ribosomal S6 kinases

Ruhcha V. Sutavani, Iain R. Phair, Rebecca Barker, Alison McFarlane, Natalia Shpiro, Stuart Lang, Andrew Woodland, J. Simon C. Arthur

J Biol Chem. 2018 Feb 16; 293(7): 2302–2317. Published online 2017 Dec 11. doi: 10.1074/jbc.M117.805424

PMCID:: PMC5818195

Abstract Article PDF–3.9M

Select item 571575915.

RSK2 phosphorylates T-bet to attenuate colon cancer metastasis and growth

Ke Yao, Cong Peng, Yuwen Zhang, Tatyana A. Zykova, Mee-Hyun Lee, Sung-Young Lee, Enyu Rao, Hanyong Chen, Joohyun Ryu, Lei Wang, Yi Zhang, Ge Gao, Wei He, Wei-Ya Ma, Kangdong Liu, Ann M. Bode, Ziming Dong, Bing Li, Zigang Dong

Proc Natl Acad Sci U S A. 2017 Nov 28; 114(48): 12791–12796. Published online 2017 Nov 13. doi: 10.1073/pnas.1710756114

PMCID:: PMC5715759

Abstract Article PDF–1.5M

Select item 510888416.

Mutation of the 3-Phosphoinositide-Dependent Protein Kinase 1 (PDK1) Substrate-Docking Site in the Developing Brain Causes Microcephaly with Abnormal Brain Morphogenesis Independently of Akt, Leading to Impaired Cognition and Disruptive Behaviors

Lluís Cordón-Barris, Sònia Pascual-Guiral, Shaobin Yang, Lydia Giménez-Llort, Silvia Lope-Piedrafita, Carlota Niemeyer, Enrique Claro, Jose M. Lizcano, Jose R. Bayascas

Mol Cell Biol. 2016 Dec 1; 36(23): 2967–2982. Prepublished online 2016 Sep 19. Published online 2016 Nov 14. doi: 10.1128/MCB.00230-16