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Items: 1 to 20 of 38

1.
Testicular ACE regulates sperm metabolism and fertilization through the transcription factor PPARγ
Tomohiro Shibata, Shabir A. Bhat, DuoYao Cao, Suguru Saito, Ellen A. Bernstein, Erika Nishi, Juliet D. Medenilla, Erica T. Wang, Jessica L. Chan, Margareta D. Pisarska, Warren G. Tourtellotte, Jorge F. Giani, Kenneth E. Bernstein, Zakir Khan
J Biol Chem. 2024 Jan; 300(1): 105486. Published online 2023 Nov 20. doi: 10.1016/j.jbc.2023.105486
PMCID:
PMC10788540
ArticlePDF–2.0M
2.
The mitochondrial pyruvate carrier (MPC) complex mediates one of three pyruvate-supplying pathways that sustain Arabidopsis respiratory metabolism
Xuyen H. Le, Chun-Pong Lee, A. Harvey Millar
Plant Cell. 2021 Aug; 33(8): 2776–2793. Published online 2021 Jun 17. doi: 10.1093/plcell/koab148
PMCID:
PMC8408480
ArticlePDF–1.6M
3.
Lactate and glutamine support NADPH generation in cancer cells under glucose deprived conditions
Minfeng Ying, Duo You, Xiaobing Zhu, Limeng Cai, Siying Zeng, Xun Hu
Redox Biol. 2021 Oct; 46: 102065. Published online 2021 Jul 11. doi: 10.1016/j.redox.2021.102065
PMCID:
PMC8321918
ArticlePDF–11M
4.
Malic Enzyme 1 Is Associated with Tumor Budding in Oral Squamous Cell Carcinomas
Chie Nakashima, Tadaaki Kirita, Kazuhiko Yamamoto, Shiori Mori, Yi Luo, Takamitsu Sasaki, Kiyomu Fujii, Hitoshi Ohmori, Isao Kawahara, Takuya Mori, Kei Goto, Shingo Kishi, Rina Fujiwara-Tani, Hiroki Kuniyasu
Int J Mol Sci. 2020 Oct; 21(19): 7149. Published online 2020 Sep 28. doi: 10.3390/ijms21197149
PMCID:
PMC7582746
ArticlePDF–2.5M
5.
Divergent effects of glutathione depletion on isocitrate dehydrogenase 1 and the pentose phosphate pathway in hamster liver
Eunsook S. Jin, Min H. Lee, Craig R. Malloy
Physiol Rep. 2020 Aug; 8(16): e14554. Published online 2020 Aug 18. doi: 10.14814/phy2.14554
PMCID:
PMC7435027
ArticlePDF–1.2M
6.
Defective NADPH production in mitochondrial disease complex I causes inflammation and cell death
Eduardo Balsa, Elizabeth A. Perry, Christopher F. Bennett, Mark Jedrychowski, Steven P. Gygi, John G. Doench, Pere Puigserver
Nat Commun. 2020; 11: 2714. Published online 2020 Jun 1. doi: 10.1038/s41467-020-16423-1
PMCID:
PMC7264245
ArticlePDF–1.2M
7.
OXPHOS remodeling in high-grade prostate cancer involves mtDNA mutations and increased succinate oxidation
Bernd Schöpf, Hansi Weissensteiner, Georg Schäfer, Federica Fazzini, Pornpimol Charoentong, Andreas Naschberger, Bernhard Rupp, Liane Fendt, Valesca Bukur, Irina Giese, Patrick Sorn, Ana Carolina Sant’Anna-Silva, Javier Iglesias-Gonzalez, Ugur Sahin, Florian Kronenberg, Erich Gnaiger, Helmut Klocker
Nat Commun. 2020; 11: 1487. Published online 2020 Mar 20. doi: 10.1038/s41467-020-15237-5
PMCID:
PMC7083862
ArticlePDF–2.0M
8.
Skeletal muscle PGC-1α1 reroutes kynurenine metabolism to increase energy efficiency and fatigue-resistance
Leandro Z. Agudelo, Duarte M. S. Ferreira, Shamim Dadvar, Igor Cervenka, Lars Ketscher, Manizheh Izadi, Liu Zhengye, Regula Furrer, Christoph Handschin, Tomas Venckunas, Marius Brazaitis, Sigitas Kamandulis, Johanna T. Lanner, Jorge L. Ruas
Nat Commun. 2019; 10: 2767. Published online 2019 Jun 24. doi: 10.1038/s41467-019-10712-0
PMCID:
PMC6591322
ArticlePDF–1.3M
9.
Rescue from galactose-induced death of Leigh Syndrome patient cells by pyruvate and NAD+
Eligio F. Iannetti, Jan A. M. Smeitink, Peter H. G. M. Willems, Julien Beyrath, Werner J. H. Koopman
Cell Death Dis. 2018 Nov; 9(11): 1135. Published online 2018 Nov 14. doi: 10.1038/s41419-018-1179-4
PMCID:
PMC6235972
ArticlePDF–2.0M
10.
Suppression of experimental cerebral malaria by disruption of malate:quinone oxidoreductase
Mamoru Niikura, Keisuke Komatsuya, Shin-Ichi Inoue, Risa Matsuda, Hiroko Asahi, Daniel Ken Inaoka, Kiyoshi Kita, Fumie Kobayashi
Malar J. 2017; 16: 247. Published online 2017 Jun 12. doi: 10.1186/s12936-017-1898-5
PMCID:
PMC5469008
ArticlePDF–2.2M
11.
NNT reverse mode of operation mediates glucose control of mitochondrial NADPH and glutathione redox state in mouse pancreatic β-cells
Laila R.B. Santos, Carole Muller, Arnaldo H. de Souza, Hilton K. Takahashi, Peter Spégel, Ian R. Sweet, Heeyoung Chae, Hindrik Mulder, Jean-Christophe Jonas
Mol Metab. 2017 Jun; 6(6): 535–547. Published online 2017 Apr 21. doi: 10.1016/j.molmet.2017.04.004
PMCID:
PMC5444111
ArticlePDF–2.8M
12.
Mass spectrometry analysis shows the biosynthetic pathways supported by pyruvate carboxylase in highly invasive breast cancer cells
Phatchariya Phannasil, Israr-ul H. Ansari, Mahmoud El Azzouny, Melissa J. Longacre, Khanti Rattanapornsompong, Charles F. Burant, Michael J. MacDonald, Sarawut Jitrapakdee
Biochim Biophys Acta. Author manuscript; available in PMC 2018 Feb 1.
Published in final edited form as: Biochim Biophys Acta. 2017 Feb; 1863(2): 537–551. Published online 2016 Nov 24. doi: 10.1016/j.bbadis.2016.11.021
PMCID:
PMC5243144
ArticlePDF–4.2M
13.
The Contribution of Nicotinamide Nucleotide Transhydrogenase to Peroxide Detoxification Is Dependent on the Respiratory State and Counterbalanced by Other Sources of NADPH in Liver Mitochondria
Juliana Aparecida Ronchi, Annelise Francisco, Luiz Augusto Correa Passos, Tiago Rezende Figueira, Roger Frigério Castilho
J Biol Chem. 2016 Sep 16; 291(38): 20173–20187. Published online 2016 Jul 29. doi: 10.1074/jbc.M116.730473
PMCID:
PMC5025700
ArticlePDF–2.7M
14.
Reactive Oxygen Species Production in Cardiac Mitochondria After Complex I Inhibition: Modulation by Substrate-Dependent Regulation of the NADH/NAD+ Ratio
Paavo Korge, Guillaume Calmettes, James N. Weiss
Free Radic Biol Med. Author manuscript; available in PMC 2017 Jul 1.
Published in final edited form as: Free Radic Biol Med. 2016 Jul; 96: 22–33. Published online 2016 Apr 9. doi: 10.1016/j.freeradbiomed.2016.04.002
PMCID:
PMC4912463
ArticlePDF–2.1M
15.
Region-Specific Defects of Respiratory Capacities in the Ndufs4(KO) Mouse Brain
Ernst-Bernhard Kayser, Margaret M. Sedensky, Philip G. Morgan
PLoS One. 2016; 11(1): e0148219. Published online 2016 Jan 29. doi: 10.1371/journal.pone.0148219
PMCID:
PMC4732614
ArticlePDF–3.1M
16.
Investigating the Roles of Mitochondrial and Cytosolic Malic Enzyme in Insulin Secretion
Rebecca L. Pongratz, Richard G. Kibbey, Gary W. Cline
Methods Enzymol. Author manuscript; available in PMC 2015 May 6.
Published in final edited form as: Methods Enzymol. 2009; 457: 425–450. doi: 10.1016/S0076-6879(09)05024-1
PMCID:
PMC4422111
ArticlePDF–1.3M
17.
SIRT3-dependent GOT2 acetylation status affects the malate–aspartate NADH shuttle activity and pancreatic tumor growth
Hui Yang, Lisha Zhou, Qian Shi, Yuzheng Zhao, Huaipeng Lin, Mengli Zhang, Shimin Zhao, Yi Yang, Zhi-Qiang Ling, Kun-Liang Guan, Yue Xiong, Dan Ye
EMBO J. 2015 Apr 15; 34(8): 1110–1125. Published online 2015 Mar 9. doi: 10.15252/embj.201591041
PMCID:
PMC4406655
ArticlePDF–1.4M
18.
Transgenic Perturbation of the Decarboxylation Phase of Crassulacean Acid Metabolism Alters Physiology and Metabolism But Has Only a Small Effect on Growth
Louisa V. Dever, Susanna F. Boxall, Jana Kneřová, James Hartwell
Plant Physiol. 2015 Jan; 167(1): 44–59. Published online 2014 Nov 5. doi: 10.1104/pp.114.251827
PMCID:
PMC4281012
ArticlePDF–1.0M
19.
Quantitative flux analysis reveals folate-dependent NADPH production
Jing Fan, Jiangbin Ye, Jurre J. Kamphorst, Tomer Shlomi, Craig B. Thompson, Joshua D. Rabinowitz
Nature. Author manuscript; available in PMC 2014 Dec 12.
Published in final edited form as: Nature. 2014 Jun 12; 510(7504): 298–302. Published online 2014 May 4. doi: 10.1038/nature13236
Correction in:
volume 513 on page 574
PMCID:
PMC4104482
ArticlePDF–2.0M
20.
Knockdown of Malic Enzyme 2 Suppresses Lung Tumor Growth, Induces Differentiation and Impacts PI3K/AKT Signaling
Jian-Guo Ren, Pankaj Seth, Clary B. Clish, Pawel K. Lorkiewicz, Richard M. Higashi, Andrew N. Lane, Teresa W.-M. Fan, Vikas P. Sukhatme
Sci Rep. 2014; 4: 5414. Published online 2014 Jun 24. doi: 10.1038/srep05414
PMCID:
PMC4067620
ArticlePDF–2.1M

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