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Select item 91610721.

Role of tumor infiltrating lymphocytes and spatial immune heterogeneity in sensitivity to PD-1 axis blockers in non-small cell lung cancer

Miguel Lopez de Rodas, Venkata Nagineni, Arvind Ravi, Ila J Datar, Mari Mino-Kenudson, German Corredor, Cristian Barrera, Lindsey Behlman, David L Rimm, Roy S Herbst, Anant Madabhushi, Jonathan W Riess, Vamsidhar Velcheti, Matthew D Hellmann, Justin Gainor, Kurt A Schalper

J Immunother Cancer. 2022; 10(6): e004440. Published online 2022 Jun 1. doi: 10.1136/jitc-2021-004440

PMCID:: PMC9161072

Article PDF–13M

Select item 75529252.

Infantile fibrosarcoma–like tumor driven by novel RBPMS-MET fusion consolidated with cabozantinib

Ajay Gupta, Jennifer A. Belsky, Kathleen M. Schieffer, Kristen Leraas, Elizabeth Varga, Sean D. McGrath, Selene C. Koo, Vincent Magrini, Richard K. Wilson, Peter White, Elaine R. Mardis, Kris R. Jatana, Catherine E. Cottrell, Bhuvana A. Setty

Cold Spring Harb Mol Case Stud. 2020 Oct; 6(5): a005645. doi: 10.1101/mcs.a005645

PMCID:: PMC7552925

Article PDF–4.8M

Select item 65495663.

Identification of aggressive Gardner syndrome phenotype associated with a de novo APC variant, c.4666dup

Patrick Kiessling, Eric Dowling, Yajue Huang, Mai Lan Ho, Karthik Balakrishnan, Brenda J. Weigel, W. Edward Highsmith, Jr., Zhiyv Niu, Lisa A. Schimmenti

Cold Spring Harb Mol Case Stud. 2019 Apr; 5(2): a003640. doi: 10.1101/mcs.a003640

PMCID:: PMC6549566

Article PDF–4.9M

Select item 107232224.

Establishment and Characterization of a TP53-Mutated Eyelid Sebaceous Carcinoma Cell Line

Xiang Gu, Ziyue Huang, Jie Chen, Yingxiu Luo, Shengfang Ge, Renbing Jia, Xin Song, Peiwei Chai, Shiqiong Xu, Xianqun Fan

Invest Ophthalmol Vis Sci. 2023 Dec; 64(15): 16. Published online 2023 Dec 14. doi: 10.1167/iovs.64.15.16

PMCID:: PMC10723222

Article PDF–2.5M

Select item 104035135.

Tasmanian devil cathelicidins exhibit anticancer activity against Devil Facial Tumour Disease (DFTD) cells

Cleopatra Petrohilos, Amanda Patchett, Carolyn J. Hogg, Katherine Belov, Emma Peel

Sci Rep. 2023; 13: 12698. Published online 2023 Aug 4. doi: 10.1038/s41598-023-39901-0

PMCID:: PMC10403513

Article PDF–3.1M

Select item 100917986.

Transmissible cancer and longitudinal telomere dynamics in Tasmanian devils (Sarcophilus harrisii)

Thomas Madsen, Marcel Klaassen, Nynke Raven, Antoine M. Dujon, Geordie Jennings, Frédéric Thomas, Rodrigo Hamede, Beata Ujvari

Mol Ecol. 2022 Dec; 31(24): 6531–6540. Published online 2022 Oct 18. doi: 10.1111/mec.16721

PMCID:: PMC10091798

Article PDF–2.9M

Select item 99073737.

Integrated Whole-Exome and Transcriptome Sequencing Indicated Dysregulation of Cholesterol Metabolism in Eyelid Sebaceous Gland Carcinoma

Yuchuan Wang, Jun Li, Peng Hao, Jing Li, Ruifang Han, Jinyong Lin, Xuan Li

Transl Vis Sci Technol. 2023 Feb; 12(2): 4. Published online 2023 Feb 3. doi: 10.1167/tvst.12.2.4

PMCID:: PMC9907373

Article PDF–2.3M

Select item 98057998.

Comparative landscape genetics reveals differential effects of environment on host and pathogen genetic structure in Tasmanian devils (Sarcophilus harrisii) and their transmissible tumor

Christopher P. Kozakiewicz, Lauren Ricci, Austin H. Patton, Amanda R. Stahlke, Sarah A. Hendricks, Mark J. Margres, Manuel Ruiz-Aravena, David G. Hamilton, Rodrigo Hamede, Hamish McCallum, Menna E. Jones, Paul A. Hohenlohe, Andrew Storfer

Mol Ecol. Author manuscript; available in PMC 2023 Jan 1.

Published in final edited form as: Mol Ecol. 2020 Sep; 29(17): 3217–3233. Published online 2020 Aug 2. doi: 10.1111/mec.15558

PMCID:: PMC9805799

Article PDF–2.2M

Select item 95799199.

Class II transactivator induces expression of MHC-I and MHC-II in transmissible Tasmanian devil facial tumours

Chrissie E. B. Ong, Yuanyuan Cheng, Hannah V. Siddle, A. Bruce Lyons, Gregory M. Woods, Andrew S. Flies

Open Biol. 2022 Oct; 12(10): 220208. Published online October 19, 2022. doi: 10.1098/rsob.220208

PMCID:: PMC9579919

Article PDF–1.4M

Select item 931080410.

Transmissible cancer influences immune gene expression in an endangered marsupial, the Tasmanian devil (Sarcophilus harrisii)

Nynke Raven, Marcel Klaassen, Thomas Madsen, Frédéric Thomas, Rodrigo K. Hamede, Beata Ujvari

Mol Ecol. 2022 Apr; 31(8): 2293–2311. Published online 2022 Mar 15. doi: 10.1111/mec.16408

PMCID:: PMC9310804

Article PDF–1.4M

Select item 910636111.

Ultrasensitive profiling of UV-induced mutations identifies thousands of subclinical facial tumors in tuberous sclerosis complex

Katarzyna Klonowska, Joannes M. Grevelink, Krinio Giannikou, Barbara A. Ogorek, Zachary T. Herbert, Aaron R. Thorner, Thomas N. Darling, Joel Moss, David J. Kwiatkowski

J Clin Invest. 2022 May 16; 132(10): e155858. Published online 2022 May 16. doi: 10.1172/JCI155858

PMCID:: PMC9106361

Article PDF–5.4M

Select item 863317212.

Round Cell Sarcoma with EWSR1-PATZ1 Fusion in the Face of a Five-Year-Old Boy: Report of a Case with Unusual Histologic Features

Derek Tsz Wai Yau, Shun Wong, Chit Chow, Ka Fai To

Head Neck Pathol. 2021 Dec; 15(4): 1350–1358. Published online 2021 Jan 18. doi: 10.1007/s12105-021-01285-w

PMCID:: PMC8633172

Article PDF–2.0M

Select item 862938013.

The differentiation state of the Schwann cell progenitor drives phenotypic variation between two contagious cancers

Rachel S. Owen, Sri H. Ramarathinam, Alistair Bailey, Annalisa Gastaldello, Kathryn Hussey, Paul J. Skipp, Anthony W. Purcell, Hannah V. Siddle

PLoS Pathog. 2021 Nov; 17(11): e1010033. Published online 2021 Nov 15. doi: 10.1371/journal.ppat.1010033

PMCID:: PMC8629380

Article PDF–2.3M

Select item 847749614.

Spatial variation in gene expression of Tasmanian devil facial tumors despite minimal host transcriptomic response to infection

Christopher P. Kozakiewicz, Alexandra K. Fraik, Austin H. Patton, Manuel Ruiz-Aravena, David G. Hamilton, Rodrigo Hamede, Hamish McCallum, Paul A. Hohenlohe, Mark J. Margres, Menna E. Jones, Andrew Storfer

BMC Genomics. 2021; 22: 698. Published online 2021 Sep 27. doi: 10.1186/s12864-021-07994-4

PMCID:: PMC8477496

Article PDF–2.0M

Select item 815001015.

Contemporary and historical selection in Tasmanian devils (Sarcophilus harrisii) support novel, polygenic response to transmissible cancer

Amanda R. Stahlke, Brendan Epstein, Soraia Barbosa, Mark J. Margres, Austin H. Patton, Sarah A. Hendricks, Anne Veillet, Alexandra K. Fraik, Barbara Schönfeld, Hamish I. McCallum, Rodrigo Hamede, Menna E. Jones, Andrew Storfer, Paul A. Hohenlohe

Proc Biol Sci. May 26, 2021; 288(1951): 20210577. Published online May 26, 2021. doi: 10.1098/rspb.2021.0577

PMCID:: PMC8150010

Article PDF–1024K

Select item 811421416.

The immunopeptidomes of two transmissible cancers and their host have a common, dominant peptide motif

Annalisa Gastaldello, Sri H. Ramarathinam, Alistair Bailey, Rachel Owen, Steven Turner, N. Kontouli, Tim Elliott, Paul Skipp, Anthony W. Purcell, Hannah V. Siddle

Immunology. 2021 Jun; 163(2): 169–184. Published online 2021 Feb 4. doi: 10.1111/imm.13307