PMC Links for Nucleotide (Select 1051671310) - PMC

Marcella Cesana, Michael H. Guo, Davide Cacchiarelli, Lara Wahlster, Jessica Barragan, Sergei Doulatov, Linda T. Vo, Beatrice Salvatori, Cole Trapnell, Kendell Clement, Patrick Cahan, Kaloyan M. Tsanov, Patricia M. Sousa, Barbara Tazon-Vega, Adriano Bolondi, Federico M. Giorgi, Andrea Califano, John L. Rinn, Alexander Meissner, Joel N. Hirschhorn, George Q. Daley

Cell Stem Cell. Author manuscript; available in PMC 2019 Apr 5.

Published in final edited form as: Cell Stem Cell. 2018 Apr 5; 22(4): 575–588.e7. doi: 10.1016/j.stem.2018.03.012

PMCID:: PMC5957284

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Select item 58721464.

Haematopoietic stem and progenitor cells from human pluripotent stem cells

Ryohichi Sugimura, Deepak Kumar Jha, Areum Han, Clara Soria-Valles, Edroaldo Lummertz da Rocha, Yi-Fen Lu, Jeremy A. Goettel, Erik Serrao, R. Grant Rowe, Mohan Malleshaiah, Irene Wong, Patricia Sousa, Ted N. Zhu, Andrea Ditadi, Gordon Keller, Alan N. Engelman, Scott B. Snapper, Sergei Doulatov, George Q. Daley

Nature. Author manuscript; available in PMC 2018 Mar 28.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 432–438. Published online 2017 May 17. doi: 10.1038/nature22370

PMCID:: PMC5872146

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Select item 58328605.

Reconstruction of complex single-cell trajectories using CellRouter

Edroaldo Lummertz da Rocha, R. Grant Rowe, Vanessa Lundin, Mohan Malleshaiah, Deepak Kumar Jha, Carlos R. Rambo, Hu Li, Trista E. North, James J. Collins, George Q. Daley

Nat Commun. 2018; 9: 892. Published online 2018 Mar 1. doi: 10.1038/s41467-018-03214-y

PMCID:: PMC5832860

Article PDF–3.6M

Select item 57854616.

Regulation of haematopoietic multipotency by EZH1

Linda T. Vo, Melissa A. Kinney, Xin Liu, Yuannyu Zhang, Jessica Barragan, Patricia M. Sousa, Deepak K. Jha, Areum Han, Marcella Cesana, Zhen Shao, Trista E. North, Stuart H. Orkin, Sergei Doulatov, Jian Xu, George Q. Daley

Nature. Author manuscript; available in PMC 2018 Jul 17.

Published in final edited form as: Nature. 2018 Jan 25; 553(7689): 506–510. Published online 2018 Jan 17. doi: 10.1038/nature25435

PMCID:: PMC5785461

Article PDF–1.7M

Select item 57375897.

Gene correction of HAX1 reversed Kostmann disease phenotype in patient-specific induced pluripotent stem cells

Erik Pittermann, Nico Lachmann, Glenn MacLean, Stephan Emmrich, Mania Ackermann, Gudrun Göhring, Brigitte Schlegelberger, Karl Welte, Axel Schambach, Dirk Heckl, Stuart H. Orkin, Tobias Cantz, Jan-Henning Klusmann

Blood Adv. 2017 Jun 13; 1(14): 903–914. Published online 2017 Jun 2. doi: 10.1182/bloodadvances.2016003798

PMCID:: PMC5737589

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Select item 55011798.

Drug discovery for Diamond-Blackfan anemia using reprogrammed hematopoietic progenitors

Sergei Doulatov, Linda T. Vo, Elizabeth R. Macari, Lara Wahlster, Melissa A. Kinney, Alison M. Taylor, Jessica Barragan, Manav Gupta, Katherine McGrath, Hsiang-Ying Lee, Jessica M. Humphries, Alex DeVine, Anupama Narla, Blanche P. Alter, Alan H. Beggs, Suneet Agarwal, Benjamin L. Ebert, Hanna T. Gazda, Harvey F. Lodish, Colin A. Sieff, Thorsten M. Schlaeger, Leonard I. Zon, George Q. Daley

Sci Transl Med. Author manuscript; available in PMC 2017 Aug 8.

Published in final edited form as: Sci Transl Med. 2017 Feb 8; 9(376): eaah5645. doi: 10.1126/scitranslmed.aah5645

PMCID:: PMC5501179

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Select item 52477989.

Engineered Murine HSCs Reconstitute Multi-lineage Hematopoiesis and Adaptive Immunity

Yi-Fen Lu, Patrick Cahan, Samantha Ross, Julie Sahalie, Patricia M. Sousa, Brandon K. Hadland, Wenqing Cai, Erik Serrao, Alan N. Engelman, Irwin D. Bernstein, George Q. Daley

Cell Rep. Author manuscript; available in PMC 2017 Jan 20.

Published in final edited form as: Cell Rep. 2016 Dec 20; 17(12): 3178–3192. doi: 10.1016/j.celrep.2016.11.077

PMCID:: PMC5247798

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Select item 498653210.

Developmental regulation of myeloerythroid progenitor function by the Lin28b–let-7–Hmga2 axis

R. Grant Rowe, Leo D. Wang, Silvia Coma, Areum Han, Ronald Mathieu, Daniel S. Pearson, Samantha Ross, Patricia Sousa, Phi T. Nguyen, Antony Rodriguez, Amy J. Wagers, George Q. Daley

J Exp Med. 2016 Jul 25; 213(8): 1497–1512. doi: 10.1084/jem.20151912

PMCID:: PMC4986532

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Select item 494620111.

Interferon-α signaling promotes embryonic HSC maturation

Peter Geon Kim, Matthew C. Canver, Catherine Rhee, Samantha J. Ross, June V. Harriss, Ho-Chou Tu, Stuart H. Orkin, Haley O. Tucker, George Q. Daley

Blood. 2016 Jul 14; 128(2): 204–216. Prepublished online 2016 Apr 19. doi: 10.1182/blood-2016-01-689281

PMCID:: PMC4946201

Article

Select item 469214112.

Hematopoietic stem cells develop in the absence of endothelial cadherin 5 expression

Heidi Anderson, Taylor C. Patch, Pavankumar N. G. Reddy, Elliott J. Hagedorn, Peter G. Kim, Kathleen A. Soltis, Michael J. Chen, Owen J. Tamplin, Maike Frye, Glenn A. MacLean, Kathleen Hübner, Daniel E. Bauer, John P. Kanki, Guillaume Vogin, Nicholas C. Huston, Minh Nguyen, Yuko Fujiwara, Barry H. Paw, Dietmar Vestweber, Leonard I. Zon, Stuart H. Orkin, George Q. Daley, Dhvanit I. Shah

Blood. 2015 Dec 24; 126(26): 2811–2820. Prepublished online 2015 Sep 18. doi: 10.1182/blood-2015-07-659276

PMCID:: PMC4692141

Article

Select item 441935513.

Flow-induced protein kinase A–CREB pathway acts via BMP signaling to promote HSC emergence

Peter Geon Kim, Haruko Nakano, Partha P. Das, Michael J. Chen, R. Grant Rowe, Stephanie S. Chou, Samantha J. Ross, Kathleen M. Sakamoto, Leonard I. Zon, Thorsten M. Schlaeger, Stuart H. Orkin, Atsushi Nakano, George Q. Daley

J Exp Med. 2015 May 4; 212(5): 633–648. doi: 10.1084/jem.20141514

PMCID:: PMC4419355

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Select item 440828914.

De novo generation of HSCs from somatic and pluripotent stem cell sources

Linda T. Vo, George Q. Daley

Blood. 2015 Apr 23; 125(17): 2641–2648. Prepublished online 2015 Mar 11. doi: 10.1182/blood-2014-10-570234

PMCID:: PMC4408289

Article

Select item 434235515.

Notch1 acts via Foxc2 to promote definitive hematopoiesis via effects on hemogenic endothelium

Il Ho Jang, Yi-Fen Lu, Long Zhao, Pamela L. Wenzel, Tsutomu Kume, Sumon M. Datta, Natasha Arora, Jordi Guiu, Mounia Lagha, Peter G. Kim, Eun Kyoung Do, Jae Ho Kim, Thorsten M. Schlaeger, Leonard I. Zon, Anna Bigas, Caroline E. Burns, George Q. Daley

Blood. 2015 Feb 26; 125(9): 1418–1426. Prepublished online 2015 Jan 13. doi: 10.1182/blood-2014-04-568170

PMCID:: PMC4342355

Article

Select item 432991316.

A comparison of non-integrating reprogramming methods

Thorsten M Schlaeger, Laurence Daheron, Thomas R Brickler, Samuel Entwisle, Karrie Chan, Amelia Cianci, Alexander DeVine, Andrew Ettenger, Kelly Fitzgerald, Michelle Godfrey, Dipti Gupta, Jade McPherson, Prerana Malwadkar, Manav Gupta, Blair Bell, Akiko Doi, Namyoung Jung, Xin Li, Maureen S Lynes, Emily Brookes, Anne B C Cherry, Didem Demirbas, Alexander M Tsankov, Leonard I Zon, Lee L Rubin, Andrew P Feinberg, Alexander Meissner, Chad A Cowan, George Q Daley

Nat Biotechnol. Author manuscript; available in PMC 2015 Feb 16.

Published in final edited form as: Nat Biotechnol. 2015 Jan; 33(1): 58–63. Published online 2014 Dec 1. doi: 10.1038/nbt.3070

PMCID:: PMC4329913

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Dissecting engineered cell types and enhancing cell fate conversion via CellNet

Samantha A. Morris, Patrick Cahan, Hu Li, Anna M. Zhao, Adrianna K. San Roman, Ramesh A. Shivdasani, James J. Collins, George Q. Daley

Cell. Author manuscript; available in PMC 2015 Aug 14.

Published in final edited form as: Cell. 2014 Aug 14; 158(4): 889–902. doi: 10.1016/j.cell.2014.07.021

PMCID:: PMC4291075

Article PDF–2.5M

Select item 423368018.

CellNet: Network Biology Applied to Stem Cell Engineering

Patrick Cahan, Hu Li, Samantha A. Morris, Edroaldo Lummertz da Rocha, George Q. Daley, James J. Collins

Cell. Author manuscript; available in PMC 2015 Aug 14.

Published in final edited form as: Cell. 2014 Aug 14; 158(4): 903–915. doi: 10.1016/j.cell.2014.07.020

PMCID:: PMC4233680

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Select item 422607119.

A nontranscriptional role for Oct4 in the regulation of mitotic entry

Rui Zhao, Richard W. Deibler, Paul H. Lerou, Andrea Ballabeni, Garrett C. Heffner, Patrick Cahan, Juli J. Unternaehrer, Marc W. Kirschner, George Q. Daley

Proc Natl Acad Sci U S A. 2014 Nov 4; 111(44): 15768–15773. Published online 2014 Oct 16. doi: 10.1073/pnas.1417518111

PMCID:: PMC4226071

Article PDF–1.2M

Select item 417239820.

Effect of developmental stage of HSC and recipient on transplant outcomes

Natasha Arora, Pamela L. Wenzel, Shannon L. McKinney-Freeman, Samantha J. Ross, Peter G. Kim, Stephanie S. Chou, Momoko Yoshimoto, Mervin C. Yoder, George Q. Daley

Dev Cell. Author manuscript; available in PMC 2015 Jun 9.

Published in final edited form as: Dev Cell. 2014 Jun 9; 29(5): 621–628. doi: 10.1016/j.devcel.2014.04.013

PMCID:: PMC4172398

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