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Items: 14

1.
Reversible Memory Loss in a Mouse Transgenic Model of Alzheimer's Disease
Linda A. Kotilinek, Brian Bacskai, Marcus Westerman, Takeshi Kawarabayashi, Linda Younkin, Bradley T. Hyman, Steven Younkin, Karen H. Ashe
J Neurosci. 2002 Aug 1; 22(15): 6331–6335. doi: 10.1523/JNEUROSCI.22-15-06331.2002
PMCID:
PMC6758140
AbstractArticlePDF–195K
2.
Downregulation of Keap1 contributes to poor prognosis and Axitinib resistance of renal cell carcinoma via upregulation of Nrf2 expression
Haipeng Huang, Yunhong Wu, Weijin Fu, Xiaoming Wang, Liquan Zhou, Xiaolong Xu, Fu Huang, Yi Wu
Int J Mol Med. 2019 May; 43(5): 2044–2054. Published online 2019 Mar 14. doi: 10.3892/ijmm.2019.4134
PMCID:
PMC6443340
AbstractArticlePDF–1.0M
3.
MicroRNA miR-24-3p Reduces Apoptosis and Regulates Keap1-Nrf2 Pathway in Mouse Cardiomyocytes Responding to Ischemia/Reperfusion Injury
Xu Xiao, Zhigang Lu, Victor Lin, Adam May, Daniel H. Shaw, Zhihao Wang, Briana Che, Kyle Tran, Hongjun Du, Peter X. Shaw
Oxid Med Cell Longev. 2018; 2018: 7042105. Published online 2018 Dec 2. doi: 10.1155/2018/7042105
PMCID:
PMC6304907
AbstractArticlePDF–1.2M
4.
DC32, a Dihydroartemisinin Derivative, Ameliorates Collagen-Induced Arthritis Through an Nrf2-p62-Keap1 Feedback Loop
Menglin Fan, Yanan Li, Chunhua Yao, Xiufeng Liu, Jihua Liu, Boyang Yu
Front Immunol. 2018; 9: 2762. Published online 2018 Nov 27. doi: 10.3389/fimmu.2018.02762
PMCID:
PMC6277526
AbstractArticlePDF–4.9M
5.
Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain
Ken Itoh, Nobunao Wakabayashi, Yasutake Katoh, Tetsuro Ishii, Kazuhiko Igarashi, James Douglas Engel, Masayuki Yamamoto
Genes Dev. 1999 Jan 1; 13(1): 76–86. doi: 10.1101/gad.13.1.76
PMCID:
PMC316370
AbstractArticlePDF–1.7M
6.
Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants
Albena T. Dinkova-Kostova, W. David Holtzclaw, Robert N. Cole, Ken Itoh, Nobunao Wakabayashi, Yasutake Katoh, Masayuki Yamamoto, Paul Talalay
Proc Natl Acad Sci U S A. 2002 Sep 3; 99(18): 11908–11913. Published online 2002 Aug 22. doi: 10.1073/pnas.172398899
PMCID:
PMC129367
AbstractArticlePDF–445K
7.
Nrf2 Deficiency Upregulates Intrarenal Angiotensin-Converting Enzyme-2 and Angiotensin 1-7 Receptor Expression and Attenuates Hypertension and Nephropathy in Diabetic Mice
Shuiling Zhao, Anindya Ghosh, Chao-Sheng Lo, Isabelle Chenier, James W. Scholey, Janos G. Filep, Julie R. Ingelfinger, Shao-Ling Zhang, John S. D. Chan
Endocrinology. 2018 Feb; 159(2): 836–852. Published online 2017 Dec 1. doi: 10.1210/en.2017-00752
PMCID:
PMC5774246
AbstractArticle
8.
Insulin Inhibits Nrf2 Gene Expression via Heterogeneous Nuclear Ribonucleoprotein F/K in Diabetic Mice
Anindya Ghosh, Shaaban Abdo, Shuiling Zhao, Chin-Han Wu, Yixuan Shi, Chao-Sheng Lo, Isabelle Chenier, Thierry Alquier, Janos G. Filep, Julie R. Ingelfinger, Shao-Ling Zhang, John S. D. Chan
Endocrinology. 2017 Apr 1; 158(4): 903–919. Published online 2017 Jan 23. doi: 10.1210/en.2016-1576
PMCID:
PMC5460794
AbstractArticle
9.
Sigma 1 Receptor regulates the oxidative stress response in primary retinal Müller glial cells via Nrf2 signaling and system xc−, the Na+-independent glutamate-cystine exchanger
J. Wang, A. Shanmugam, S. Markand, E. Zorrilla, V. Ganapathy, S.B. Smith
Free Radic Biol Med. Author manuscript; available in PMC 2016 Sep 1.
Published in final edited form as: Free Radic Biol Med. 2015 Sep; 86: 25–36. Published online 2015 Apr 25. doi: 10.1016/j.freeradbiomed.2015.04.009
PMCID:
PMC4554890
AbstractArticlePDF–1.4M
10.
Candidate genes for limiting cholestatic intestinal injury identified by gene expression profiling
Samuel M Alaish, Jennifer Timmons, Alexis Smith, Marguerite S Buzza, Ebony Murphy, Aiping Zhao, Yezhou Sun, Douglas J Turner, Terez Shea-Donahue, Toni M Antalis, Alan Cross, Susan G Dorsey
Physiol Rep. 2013 Sep; 1(4): e00073. Published online 2013 Sep 17. doi: 10.1002/phy2.73
PMCID:
PMC3808870
AbstractArticlePDF–1.2M
11.
Activation of the Nrf2-ARE pathway by siRNA knockdown of Keap1 reduces oxidative stress and provides partial protection from MPTP-mediated neurotoxicity
Tracy P. Williamson, Delinda A. Johnson, Jeffrey A. Johnson
Neurotoxicology. Author manuscript; available in PMC 2013 Jun 1.
Published in final edited form as: Neurotoxicology. 2012 Jun; 33(3): 272–279. Published online 2012 Feb 9. doi: 10.1016/j.neuro.2012.01.015
PMCID:
PMC3521526
AbstractArticlePDF–972K
12.
Regulatory Role of KEAP1 and NRF2 in PPARγ Expression and Chemoresistance in Human Non-small Cell Lung Carcinoma Cells
Lijuan Zhan, Hao Zhang, Qiang Zhang, Courtney G. Woods, Yanyan Chen, Peng Xue, Jian Dong, Erik J. Tokar, Yuanyuan Xu, Yongyong Hou, Jingqi Fu, Kathy Yarborough, Aiping Wang, Weidong Qu, Michael P. Waalkes, Melvin E. Andersen, Jingbo Pi
Free Radic Biol Med. Author manuscript; available in PMC 2013 Aug 15.
Published in final edited form as: Free Radic Biol Med. 2012 Aug 15; 53(4): 758–768. Published online 2012 Jun 7. doi: 10.1016/j.freeradbiomed.2012.05.041
Correction in:
Free Radic Biol Med. 2021 Nov 29
PMCID:
PMC3418425
AbstractArticlePDF–3.4M
13.
Deficiency in the Nuclear Factor E2-related Factor-2 Transcription Factor Results in Impaired Adipogenesis and Protects against Diet-induced Obesity
Jingbo Pi, Laura Leung, Peng Xue, Weiping Wang, Yongyong Hou, Dianxin Liu, Einav Yehuda-Shnaidman, Candy Lee, Jackie Lau, Theodore W. Kurtz, Jefferson Y. Chan
J Biol Chem. 2010 Mar 19; 285(12): 9292–9300. Published online 2010 Jan 20. doi: 10.1074/jbc.M109.093955
PMCID:
PMC2838347
AbstractArticlePDF–2.0M
14.
Novel design and controls for focused DNA microarrays: applications in quality assurance/control and normalization for the Health Canada ToxArray™
Carole L Yauk, Andrew Williams, Sherri Boucher, Lynn M Berndt, Gu Zhou, Jenny L Zheng, Andrea Rowan-Carroll, Hongyan Dong, Iain B Lambert, George R Douglas, Craig L Parfett
BMC Genomics. 2006; 7: 266. Published online 2006 Oct 19. doi: 10.1186/1471-2164-7-266
PMCID:
PMC1635050
AbstractArticlePDF–567K

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