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Select item 63603521.

Retinal Vascular Abnormalities and Microglia Activation in Mice with Deficiency in Cytochrome P450 46A1–Mediated Cholesterol Removal

Aicha Saadane, Natalia Mast, George Trichonas, Dibyendu Chakraborty, Sandra Hammer, Julia V. Busik, Maria B. Grant, Irina A. Pikuleva

Am J Pathol. 2019 Feb; 189(2): 405–425. doi: 10.1016/j.ajpath.2018.10.013

PMCID:: PMC6360352

Article

Select item 63271532.

Additional pathways of sterol metabolism: Evidence from analysis of Cyp27a1−/− mouse brain and plasma

William J. Griffiths, Peter J. Crick, Anna Meljon, Spyridon Theofilopoulos, Jonas Abdel-Khalik, Eylan Yutuc, Josie E. Parker, Diane E. Kelly, Steven L. Kelly, Ernest Arenas, Yuqin Wang

Biochim Biophys Acta Mol Cell Biol Lipids. 2019 Feb; 1864(2): 191–211. doi: 10.1016/j.bbalip.2018.11.006

PMCID:: PMC6327153

Article

Select item 57841763.

Sterol 27-hydroxylase gene dosage and the antiatherosclerotic effect of Rifampicin in mice

Line Zurkinden, Dmitri Sviridov, Bruno Vogt, Geneviève Escher

Biosci Rep. 2018 Feb 28; 38(1): BSR20171162. Prepublished online 2017 Nov 30. Published online 2018 Jan 25. doi: 10.1042/BSR20171162

PMCID:: PMC5784176

Article PDF–2.8M

Select item 56368794.

The cholesterol metabolite 27 hydroxycholesterol facilitates breast cancer metastasis through its actions on immune cells

Amy E. Baek, Yen-Rei A. Yu, Sisi He, Suzanne E. Wardell, Ching-Yi Chang, Sanghoon Kwon, Ruchita V. Pillai, Hannah B. McDowell, J. Will Thompson, Laura G. Dubois, Patrick M. Sullivan, Jongsook K. Kemper, Michael D. Gunn, Donald P. McDonnell, Erik R. Nelson

Nat Commun. 2017; 8: 864. Published online 2017 Oct 11. doi: 10.1038/s41467-017-00910-z

PMCID:: PMC5636879

Article PDF–672K

Select item 44497245.

Mutations in the Bile Acid Biosynthetic Enzyme Sterol 27-Hydroxylase Underlie Cerebrotendinous Xanthomatosis

James J. Cali, Chih-Lin Hsieh, Uta Francke, David W. Russell

J Biol Chem. Author manuscript; available in PMC 2015 May 30.

Published in final edited form as: J Biol Chem. 1991 Apr 25; 266(12): 7779–7783.

PMCID:: PMC4449724

Article PDF–579K

Select item 56464196.

Distinct oxysterol requirements for positioning naïve and activated dendritic cells in the spleen

Erick Lu, Eric V. Dang, Jeffrey G. McDonald, Jason G. Cyster

Sci Immunol. Author manuscript; available in PMC 2017 Oct 18.

Published in final edited form as: Sci Immunol. 2017 Apr 7; 2(10): eaal5237. doi: 10.1126/sciimmunol.aal5237

PMCID:: PMC5646419

Article PDF–3.6M

Select item 56335887.

Metabolomic and transcriptomic profiling of hepatocellular carcinomas in Hras12V transgenic mice

Tingting Fan, Zhuona Rong, Jianyi Dong, Juan Li, Kangwei Wang, Xinxin Wang, Huiling Li, Jun Chen, Fujin Wang, Jingyu Wang, Aiguo Wang

Cancer Med. 2017 Oct; 6(10): 2370–2384. Published online 2017 Sep 21. doi: 10.1002/cam4.1177

PMCID:: PMC5633588

Article PDF–721K

Select item 53777768.

Berberine-induced Inactivation of Signal Transducer and Activator of Transcription 5 Signaling Promotes Male-specific Expression of a Bile Acid Uptake Transporter

Pengli Bu, Yuan Le, Yue Zhang, Youcai Zhang, Xingguo Cheng

J Biol Chem. 2017 Mar 17; 292(11): 4602–4613. Published online 2017 Feb 1. doi: 10.1074/jbc.M116.757567

PMCID:: PMC5377776

Article PDF–2.9M

Select item 47609249.

Lack of endogenous cholecystokinin promotes cholelithogenesis in mice

Helen H. Wang, Min Liu, Piero Portincasa, Patrick Tso, David Q.-H. Wang

Neurogastroenterol Motil. Author manuscript; available in PMC 2017 Mar 1.

Published in final edited form as: Neurogastroenterol Motil. 2016 Mar; 28(3): 364–375. Published online 2015 Nov 25. doi: 10.1111/nmo.12734

PMCID:: PMC4760924

Article PDF–1.3M

Select item 470104110.

The deletion of the estrogen receptor α gene reduces susceptibility to estrogen-induced cholesterol cholelithiasis in female mice

Ornella de Bari, Helen H. Wang, Piero Portincasa, Min Liu, David Q.-H. Wang

Biochim Biophys Acta. Author manuscript; available in PMC 2016 Oct 1.

Published in final edited form as: Biochim Biophys Acta. 2015 Oct; 1852(10 0 0): 2161–2169. Published online 2015 Jul 30. doi: 10.1016/j.bbadis.2015.07.020

PMCID:: PMC4701041

Article PDF–1.7M

Select item 402926611.

Lack of P2Y₁₃ in mice fed a high cholesterol diet results in decreased hepatic cholesterol content, biliary lipid secretion and reverse cholesterol transport

Laeticia Lichtenstein, Nizar Serhan, Wijtske Annema, Guillaume Combes, Bernard Robaye, Jean-Marie Boeynaems, Bertrand Perret, Uwe J F Tietge, Muriel Laffargue, Laurent O Martinez

Nutr Metab (Lond) 2013; 10: 67. Published online 2013 Nov 6. doi: 10.1186/1743-7075-10-67

PMCID:: PMC4029266

Article PDF–338K

Select item 340457112.

Delineation of biochemical, molecular, and physiological changes accompanying bile acid pool size restoration in Cyp7a1^−/− mice fed low levels of cholic acid

Ryan D. Jones, Joyce J. Repa, David W. Russell, John M. Dietschy, Stephen D. Turley

Am J Physiol Gastrointest Liver Physiol. 2012 Jul 15; 303(2): G263–G274. Published online 2012 May 24. doi: 10.1152/ajpgi.00111.2012

PMCID:: PMC3404571

Article

Select item 337274713.

Delayed activation of host innate immune pathways in streptozotocin-induced diabetic hosts leads to more severe disease during infection with Burkholderia pseudomallei

Chui-Yoke Chin, Denise M Monack, Sheila Nathan

Immunology. 2012 Apr; 135(4): 312–332. doi: 10.1111/j.1365-2567.2011.03544.x

PMCID:: PMC3372747

Article PDF–630K

Select item 316588914.

Synthesis of Hydroxylated Sterols in Transgenic Arabidopsis Plants Alters Growth and Steroid Metabolism

Lisa Beste, Nurun Nahar, Kerstin Dalman, Shozo Fujioka, Lisbeth Jonsson, Paresh C. Dutta, Folke Sitbon

Plant Physiol. 2011 Sep; 157(1): 426–440. Published online 2011 Jul 11. doi: 10.1104/pp.111.171199

PMCID:: PMC3165889

Article PDF–876K

Select item 313701615.

Cholesterol 25-hydroxylation activity of CYP3A

Akira Honda, Teruo Miyazaki, Tadashi Ikegami, Junichi Iwamoto, Tomomi Maeda, Takeshi Hirayama, Yoshifumi Saito, Tamio Teramoto, Yasushi Matsuzaki

J Lipid Res. 2011 Aug; 52(8): 1509–1516. doi: 10.1194/jlr.M014084

PMCID:: PMC3137016

Article PDF–773K

Select item 295469316.

Intermittent Hypoxia Mobilizes Bone Marrow-Derived Very Small Embryonic-Like Stem Cells and Activates Developmental Transcriptional Programs in Mice

Sina A. Gharib, Ehab A. Dayyat, Abdelnaby Khalyfa, Jinkwan Kim, Heather B. Clair, Magdalena Kucia, David Gozal

Sleep. 2010 Nov 1; 33(11): 1439–1446. doi: 10.1093/sleep/33.11.1439

PMCID:: PMC2954693

Article PDF–1.7M

Select item 286608217.

Marked variability in hepatic expression of cytochromes CYP7A1 and CYP27A1 as compared to cerebral CYP46A1. Lessons from a dietary study with omega 3 fatty acids in hamsters

Natalia Mast, Marjan Shafaati, Wahiduz Zaman, Wenchao Zheng, Deborah Prusak, Thomas Wood, G. A. S. Ansari, Anita Lövgren-Sandblom, Maria Olin, Ingemar Bjorkhem, Irina Pikuleva

Biochim Biophys Acta. Author manuscript; available in PMC 2011 Jun 1.

Published in final edited form as: Biochim Biophys Acta. 2010 Jun; 1801(6): 674–681. Published online 2010 Mar 16. doi: 10.1016/j.bbalip.2010.03.005

PMCID:: PMC2866082

Article PDF–471K

Select item 285857818.

Gene Expression Profiling Reveals Early Cellular Responses to Intracellular Magnetic Labeling with Superparamagnetic Iron Oxide Nanoparticles

Dorota A. Kedziorek, Naser Muja, Piotr Walczak, Jesus Ruiz-Cabello, Assaf A. Gilad, Chunfa C. Jie, Jeff W. M. Bulte

Magn Reson Med. Author manuscript; available in PMC 2010 Apr 22.

Published in final edited form as: Magn Reson Med. 2010 Apr; 63(4): 1031–1043. doi: 10.1002/mrm.22290

PMCID:: PMC2858578

Article PDF–1.7M

Select item 274728019.

Global Transcriptional Response to Hfe Deficiency and Dietary Iron Overload in Mouse Liver and Duodenum

Alejandra Rodriguez, Tiina Luukkaala, Robert E. Fleming, Robert S. Britton, Bruce R. Bacon, Seppo Parkkila

PLoS One. 2009; 4(9): e7212. Published online 2009 Sep 29. doi: 10.1371/journal.pone.0007212

PMCID:: PMC2747280

Article PDF–257K

Select item 271932220.

Decreased Expression of Cholesterol 7α-Hydroxylase and Altered Bile Acid Metabolism in Apobec-1^−/− Mice Lead to Increased Gallstone Susceptibility

Yan Xie, Valerie Blanc, Thomas A. Kerr, Susan Kennedy, Jianyang Luo, Elizabeth P. Newberry, Nicholas O. Davidson

J Biol Chem. 2009 Jun 19; 284(25): 16860–16871. Published online 2009 Apr 22. doi: 10.1074/jbc.M109.010173

PMCID:: PMC2719322

Article PDF–651K

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