PMC Articles for PubChem Compound (Select 24752728) - PMC

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Items: 20

Select item 107580891.

Inhibition of the HMGB1/RAGE axis protects against cisplatin-induced ototoxicity via suppression of inflammation and oxidative stress

Xiangyun Qiao, Wen Li, Zhiwei Zheng, Chang Liu, Liping Zhao, Yingzi He, Huawei Li

Int J Biol Sci. 2024; 20(2): 784–800. Published online 2024 Jan 1. doi: 10.7150/ijbs.82003

PMCID:: PMC10758089

Article PDF–9.2M

Select item 106663372.

Local perfusion of capillaries reveals disrupted beta-amyloid homeostasis at the blood-brain barrier in Tg2576 murine Alzheimer’s model

Amira Sayed Hanafy, Alf Lamprecht, Dirk Dietrich

Fluids Barriers CNS. 2023; 20: 85. Published online 2023 Nov 22. doi: 10.1186/s12987-023-00492-7

PMCID:: PMC10666337

Article PDF–8.0M

Select item 88558313.

Impairing RAGE signaling promotes survival and limits disease pathogenesis following SARS-CoV-2 infection in mice

Forrest Jessop, Benjamin Schwarz, Dana Scott, Lydia M. Roberts, Eric Bohrnsen, John R. Hoidal, Catharine M. Bosio

JCI Insight. 2022 Jan 25; 7(2): e155896. Published online 2022 Jan 25. doi: 10.1172/jci.insight.155896

PMCID:: PMC8855831

Article PDF–11M

Select item 88328634.

RAGE mediates airway inflammation via the HDAC1 pathway in a toluene diisocyanate-induced murine asthma model

Xianru Peng, Minyu Huang, Wenqu Zhao, Zihan Lan, Xiaohua Wang, Yafei Yuan, Bohou Li, Changhui Yu, Laiyu Liu, Hangming Dong, Shaoxi Cai, Haijin Zhao

BMC Pulm Med. 2022; 22: 61. Published online 2022 Feb 11. doi: 10.1186/s12890-022-01832-3

PMCID:: PMC8832863

Article PDF–18M

Select item 85275215.

A Catecholaldehyde Metabolite of Norepinephrine Induces Myofibroblast Activation and Toxicity via the Receptor for Advanced Glycation Endproducts: Mitigating Role of l-Carnosine

T. Blake Monroe, Ethan J. Anderson

Chem Res Toxicol. 2021 Oct 18; 34(10): 2194–2201. Published online 2021 Oct 5. doi: 10.1021/acs.chemrestox.1c00262

PMCID:: PMC8527521

Article PDF–2.5M

Select item 85039186.

Environmental Microcystin exposure in underlying NAFLD-induced exacerbation of neuroinflammation, blood-brain barrier dysfunction, and neurodegeneration are NLRP3 and S100B dependent.

Ayan Mondal, Punnag Saha, Dipro Bose, Somdatta Chatterjee, Ratanesh K. Seth, Shuo Xiao, Dwayne E. Porter, Bryan Brooks, Geoff I. Scott, Mitzi Nagarkatti, Prakash Nagarkatti, Saurabh Chatterjee

Toxicology. Author manuscript; available in PMC 2022 Sep 1.

Published in final edited form as: Toxicology. 2021 Sep; 461: 152901. Published online 2021 Aug 17. doi: 10.1016/j.tox.2021.152901

PMCID:: PMC8503918

Article PDF–1.6M

Select item 84925167.

A fragment-based approach to discovery of Receptor for Advanced Glycation End products inhibitors

Natalia Kozlyuk, Benjamin A. Gilston, Lauren E. Salay, Rocco D. Gogliotti, Plamen P. Christov, Kwangho Kim, Mohiuddin Ovee, Alex G. Waterson, Walter J. Chazin

Proteins. Author manuscript; available in PMC 2022 Nov 1.

Published in final edited form as: Proteins. 2021 Nov; 89(11): 1399–1412. Published online 2021 Jul 2. doi: 10.1002/prot.26162

PMCID:: PMC8492516

Article PDF–2.1M

Select item 81496628.

Engineered cardiac tissues: a novel in vitro model to investigate the pathophysiology of mouse diabetic cardiomyopathy

Xiang Wang, Xin-xin Chen, Hai-tao Yu, Yi Tan, Qian Lin, Bradley B. Keller, Yang Zheng, Lu Cai

Acta Pharmacol Sin. 2021 Jun; 42(6): 932–941. Published online 2020 Oct 9. doi: 10.1038/s41401-020-00538-8

PMCID:: PMC8149662

Article PDF–3.9M

Select item 81164059.

Receptor for Advanced Glycation End Products (RAGE) Mediates Cognitive Impairment Triggered by Pneumococcal Meningitis

Vijayasree V. Giridharan, Jaqueline S. Generoso, Allan Collodel, Diogo Dominguini, Cristiano Julio Faller, Flavio Tardin, Gursimrat S. Bhatti, Fabricia Petronilho, Felipe Dal-Pizzol, Tatiana Barichello

Neurotherapeutics. 2021 Jan; 18(1): 640–653. Published online 2020 Sep 4. doi: 10.1007/s13311-020-00917-3

PMCID:: PMC8116405

Article PDF–2.8M

Select item 805233910.

Lipopolysaccharides induce a RAGE-mediated sensitization of sensory neurons and fluid hypersecretion in the upper airways

Manoj Nair, Santosh Jagadeeshan, George Katselis, Xiaojie Luan, Zeinab Momeni, Nicolas Henao-Romero, Paulos Chumala, Julian S. Tam, Yasuhiko Yamamoto, Juan P. Ianowski, Verónica A. Campanucci

Sci Rep. 2021; 11: 8336. Published online 2021 Apr 16. doi: 10.1038/s41598-021-86069-6

PMCID:: PMC8052339

Article PDF–2.1M

Select item 796178611.

Magic Peptide: Unique Properties of the LRR11 Peptide in the Activation of Leukotriene Synthesis in Human Neutrophils

Galina M. Viryasova, Ekaterina A. Golenkina, Tibor Hianik, Nataliya V. Soshnikova, Nina G. Dolinnaya, Tatjana V. Gaponova, Yulia M. Romanova, Galina F. Sud’ina

Int J Mol Sci. 2021 Mar; 22(5): 2671. Published online 2021 Mar 6. doi: 10.3390/ijms22052671

PMCID:: PMC7961786

Article PDF–9.0M

Select item 745367612.

Inhibitor of RAGE and glucose-induced inflammation in bone marrow mesenchymal stem cells: Effect and mechanism of action

Mengyi Jiang, Xuemei Wang, Pin Wang, Wei Peng, Bo Zhang, Ling Guo

Mol Med Rep. 2020 Oct; 22(4): 3255–3262. Published online 2020 Aug 7. doi: 10.3892/mmr.2020.11422

PMCID:: PMC7453676

Article PDF–585K

Select item 674394913.

晚期糖基化终末产物受体促进甲苯二异氰酸脂哮喘小鼠MUC5AC表达及气道黏液高分泌

熊婧, 赵文驱, 黄国华, 姚利红, 董航明, 余常辉, 赵海金, 蔡绍曦

Nan Fang Yi Ke Da Xue Xue Bao. 2017 Oct 20; 37(10): 1301–1307. Chinese. doi: 10.3969/j.issn.1673-4254.2017.10.04

PMCID:: PMC6743949

Article PDF–895K

Select item 667639314.

Amyloidogenic medin induces endothelial dysfunction and vascular inflammation through the receptor for advanced glycation endproducts

Raymond Q. Migrino, Hannah A. Davies, Seth Truran, Nina Karamanova, Daniel A. Franco, Thomas G. Beach, Geidy E. Serrano, Danh Truong, Mehdi Nikkhah, Jillian Madine

Cardiovasc Res. 2017 Sep; 113(11): 1389–1402. Published online 2017 Jul 20. doi: 10.1093/cvr/cvx135

PMCID:: PMC6676393

Article PDF–1.5M

Select item 633879915.

RAGE is a Critical Mediator of Pulmonary Oxidative Stress, Alveolar Macrophage Activation and Emphysema in Response to Cigarette Smoke

Karl A. Sanders, Don A. Delker, Tom Huecksteadt, Emily Beck, Tanna Wuren, Yuntian Chen, Yuxia Zhang, Mark W. Hazel, John R. Hoidal

Sci Rep. 2019; 9: 231. Published online 2019 Jan 18. doi: 10.1038/s41598-018-36163-z

PMCID:: PMC6338799

Article PDF–2.5M

Select item 598678216.

RAGE-dependent mitochondria pathway: a novel target of silibinin against apoptosis of osteoblastic cells induced by advanced glycation end products

Y. X. Mao, W. J. Cai, X. Y. Sun, P. P. Dai, X. M. Li, Q. Wang, X. L. Huang, B. He, P. P. Wang, G. Wu, J. F. Ma, S. B. Huang

Cell Death Dis. 2018 Jun; 9(6): 674. Published online 2018 Jun 4. doi: 10.1038/s41419-018-0718-3

PMCID:: PMC5986782

Article PDF–2.2M

Select item 551499417.

Amyloid proteotoxicity initiates an inflammatory response blocked by cannabinoids

Antonio Currais, Oswald Quehenberger, Aaron M Armando, Daniel Daugherty, Pam Maher, David Schubert

NPJ Aging Mech Dis. 2016; 2: 16012. Published online 2016 Jun 23. doi: 10.1038/npjamd.2016.12

PMCID:: PMC5514994

Article PDF–1.8M

Select item 460991818.

High-mobility group box 1 inhibits HCO₃⁻ absorption in medullary thick ascending limb through a basolateral receptor for advanced glycation end products pathway

David W. Good, Thampi George, Bruns A. Watts, III

Am J Physiol Renal Physiol. 2015 Oct 15; 309(8): F720–F730. Published online 2015 Jul 15. doi: 10.1152/ajprenal.00227.2015

PMCID:: PMC4609918

Article

Select item 395527519.

Ascorbate Reverses High Glucose- and RAGE-induced Leak of the Endothelial Permeability Barrier

M. Elizabeth Meredith, Zhi-chao Qu, James M. May

Biochem Biophys Res Commun. Author manuscript; available in PMC 2015 Feb 28.

Published in final edited form as: Biochem Biophys Res Commun. 2014 Feb 28; 445(1): 30–35. Published online 2014 Jan 25. doi: 10.1016/j.bbrc.2014.01.078

PMCID:: PMC3955275

Article PDF–1.2M

Select item 331444920.

A multimodal RAGE-specific inhibitor reduces amyloid β–mediated brain disorder in a mouse model of Alzheimer disease

Rashid Deane, Itender Singh, Abhay P. Sagare, Robert D. Bell, Nathan T. Ross, Barbra LaRue, Rachal Love, Sheldon Perry, Nicole Paquette, Richard J. Deane, Meenakshisundaram Thiyagarajan, Troy Zarcone, Gunter Fritz, Alan E. Friedman, Benjamin L. Miller, Berislav V. Zlokovic

J Clin Invest. 2012 Apr 2; 122(4): 1377–1392. Published online 2012 Mar 12. doi: 10.1172/JCI58642