PMC Articles for PubChem Compound (Select 71729975) - PMC

Result Filters

Links from PubChem Compound

Items: 1 to 20 of 55

<< First< Prev

Page of 3

Next >Last >>

Select item 109012511.

Antitumoral Potential of the Histone Demethylase Inhibitor GSK-J4 in Retinoblastoma

Yanyan Zhang, Weiqi Wu, Caixia Xu, Hongwei Yang, Guofu Huang

Invest Ophthalmol Vis Sci. 2024 Feb; 65(2): 34. Published online 2024 Feb 23. doi: 10.1167/iovs.65.2.34

PMCID:: PMC10901251

Article PDF–5.5M

Select item 104011172.

Donafenib and GSK‐J4 Synergistically Induce Ferroptosis in Liver Cancer by Upregulating HMOX1 Expression

Chenyang Zheng, Bo Zhang, Yunyun Li, Kejia Liu, Wei Wei, Shuhang Liang, Hongrui Guo, Kun Ma, Yao Liu, Jiabei Wang, Lianxin Liu

Adv Sci (Weinh) 2023 Aug; 10(22): 2206798. Published online 2023 Jun 17. doi: 10.1002/advs.202206798

PMCID:: PMC10401117

Article PDF–5.7M

Select item 101974253.

Inhibition of H3K27me3 demethylases promotes plasmablast formation

Anna K. Kania, Muyao Guo, Christopher D. Scharer, Jeremy M. Boss

Immunohorizons. Author manuscript; available in PMC 2023 May 19.

Published in final edited form as: Immunohorizons. 2021 Dec 8; 5(12): 918–930. Published online 2021 Dec 8. doi: 10.4049/immunohorizons.2000087

PMCID:: PMC10197425

Article PDF–1.7M

Select item 94411844.

Development and Validation of the TGx-HDACi Transcriptomic Biomarker to Detect Histone Deacetylase Inhibitors in Human TK6 Cells

Eunnara Cho, Andrea Rowan-Carroll, Andrew Williams, J. Christopher Corton, Heng Hong Li, Albert Fornace, Jr., Cheryl Hobbs, Carole L. Yauk

Arch Toxicol. Author manuscript; available in PMC 2022 Sep 4.

Published in final edited form as: Arch Toxicol. 2021 May; 95(5): 1631–1645. Published online 2021 Mar 26. doi: 10.1007/s00204-021-03014-2

PMCID:: PMC9441184

Article PDF–1.1M

Select item 94090905.

The Histone Demethylase Inhibitor GSK-J4 Is a Therapeutic Target for the Kidney Fibrosis of Diabetic Kidney Disease via DKK1 Modulation

Peir-Haur Hung, Yung-Chien Hsu, Tsung-Hsien Chen, Cheng Ho, Chun-Liang Lin

Int J Mol Sci. 2022 Aug; 23(16): 9407. Published online 2022 Aug 20. doi: 10.3390/ijms23169407

PMCID:: PMC9409090

Article PDF–4.6M

Select item 90164806.

Effects of GSK-J4 on JMJD3 Histone Demethylase in Mouse Prostate Cancer Xenografts

ANNA SANCHEZ, FRÉDÉRIQUE PENAULT-LLORCA, YVES-JEAN BIGNON, LAURENT GUY, DOMINIQUE BERNARD-GALLON

Cancer Genomics Proteomics. 2022 May-Jun; 19(3): 339–349. Published online 2022 May 3. doi: 10.21873/cgp.20324

PMCID:: PMC9016480

Article PDF–4.0M

Select item 88879997.

Lysine demethylase KDM6B regulates HIF-1α-mediated systemic and cellular responses to intermittent hypoxia

Jayasri Nanduri, Ning Wang, Benjamin L. Wang, Nanduri R. Prabhakar

Physiol Genomics. 2021 Sep 1; 53(9): 385–394. Published online 2021 Jul 23. doi: 10.1152/physiolgenomics.00045.2021

PMCID:: PMC8887999

Article

Select item 88515688.

Inhibiting KDM6A Demethylase Represses Long Non-Coding RNA Hotairm1 Transcription in MDSC During Sepsis

Isatou Bah, Dima Youssef, Zhi Q. Yao, Charles E. McCall, Mohamed El Gazzar

Front Immunol. 2022; 13: 823660. Published online 2022 Jan 28. doi: 10.3389/fimmu.2022.823660

PMCID:: PMC8851568

Article PDF–1.6M

Select item 85627859.

Inhibition of the H3K27 demethylase UTX enhances the epigenetic silencing of HIV proviruses and induces HIV-1 DNA hypermethylation but fails to permanently block HIV reactivation

Kien Nguyen, Curtis Dobrowolski, Meenakshi Shukla, Won-Kyung Cho, Benjamin Luttge, Jonathan Karn

PLoS Pathog. 2021 Oct; 17(10): e1010014. Published online 2021 Oct 21. doi: 10.1371/journal.ppat.1010014

PMCID:: PMC8562785

Article PDF–3.1M

Select item 852944610.

Pharmacological Inhibition of Core Regulatory Circuitry Liquid–liquid Phase Separation Suppresses Metastasis and Chemoresistance in Osteosarcoma

Bing Lu, Changye Zou, Meiling Yang, Yangyang He, Jincan He, Chuanxia Zhang, Siyun Chen, Jiaming Yu, Kilia Yun Liu, Qi Cao, Wei Zhao

Adv Sci (Weinh) 2021 Oct; 8(20): 2101895. Published online 2021 Aug 25. doi: 10.1002/advs.202101895

PMCID:: PMC8529446

Article PDF–5.3M

Select item 845110611.

Histone modification of pain-related gene expression in spinal cord neurons under a persistent postsurgical pain-like state by electrocautery

Yosuke Katsuda, Kenichi Tanaka, Tomohisa Mori, Michiko Narita, Hideyuki Takeshima, Takashige Kondo, Yoshiyuki Yamabe, Misa Matsufuji, Daisuke Sato, Yusuke Hamada, Keisuke Yamaguchi, Toshikazu Ushijima, Eiichi Inada, Naoko Kuzumaki, Masako Iseki, Minoru Narita

Mol Brain. 2021; 14: 146. Published online 2021 Sep 20. doi: 10.1186/s13041-021-00854-y

PMCID:: PMC8451106

Article PDF–1.4M

Select item 828018512.

SMARCA4 deficient tumours are vulnerable to KDM6A/UTX and KDM6B/JMJD3 blockade

Octavio A. Romero, Andrea Vilarrubi, Juan J. Alburquerque-Bejar, Antonio Gomez, Alvaro Andrades, Deborah Trastulli, Eva Pros, Fernando Setien, Sara Verdura, Lourdes Farré, Juan F. Martín-Tejera, Paula Llabata, Ana Oaknin, Maria Saigi, Josep M. Piulats, Xavier Matias-Guiu, Pedro P. Medina, August Vidal, Alberto Villanueva, Montse Sanchez-Cespedes

Nat Commun. 2021; 12: 4319. Published online 2021 Jul 14. doi: 10.1038/s41467-021-24618-3

PMCID:: PMC8280185

Article PDF–5.6M

Select item 813026813.

KDM6B promotes ESCC cell proliferation and metastasis by facilitating C/EBPβ transcription

Mei Qin, Fei Han, Jian Wu, Feng-xia Gao, Yuan Li, De-xin Yan, Xue-mei He, Yang Long, Xiao-ping Tang, De-lian Ren, Yan Gao, Tian-yang Dai

BMC Cancer. 2021; 21: 559. Published online 2021 May 17. doi: 10.1186/s12885-021-08282-w

Correction in:: BMC Cancer. 2021; 21: 893.

PMCID:: PMC8130268

Article PDF–2.7M

Select item 791435714.

KDM6B-mediated histone demethylation of LDHA promotes lung metastasis of osteosarcoma

Yuhang Jiang, Fengfeng Li, Bowen Gao, Mengjun Ma, Meng Chen, Yanfeng Wu, Weidong Zhang, Yangbai Sun, Sanhong Liu, Huiyong Shen

Theranostics. 2021; 11(8): 3868–3881. Published online 2021 Feb 6. doi: 10.7150/thno.53347

PMCID:: PMC7914357

Article PDF–3.0M

Select item 790719115.

A KDM6 inhibitor potently induces ATF4 and its target gene expression through HRI activation and by UTX inhibition

Shojiro Kitajima, Wendi Sun, Kian Leong Lee, Jolene Caifeng Ho, Seiichi Oyadomari, Takashi Okamoto, Hisao Masai, Lorenz Poellinger, Hiroyuki Kato

Sci Rep. 2021; 11: 4538. Published online 2021 Feb 25. doi: 10.1038/s41598-021-83857-y

PMCID:: PMC7907191

Article PDF–2.7M

Select item 780905616.

The demethylase inhibitor GSK-J4 limits inflammatory colitis by promoting de novo synthesis of retinoic acid in dendritic cells

Cristian Doñas, Jocelyn Neira, Francisco Osorio-Barrios, Macarena Carrasco, Dominique Fernández, Carolina Prado, Alejandra Loyola, Rodrigo Pacheco, Mario Rosemblatt

Sci Rep. 2021; 11: 1342. Published online 2021 Jan 14. doi: 10.1038/s41598-020-79122-3

PMCID:: PMC7809056

Article PDF–2.6M

Select item 768108517.

Histone H3K27 methyltransferase EZH2 and demethylase JMJD3 regulate hepatic stellate cells activation and liver fibrosis

Yan Jiang, Chan Xiang, Fan Zhong, Yang Zhang, Liyan Wang, Yuanyuan Zhao, Jiucun Wang, Chen Ding, Li Jin, Fuchu He, Haijian Wang

Theranostics. 2021; 11(1): 361–378. Published online 2021 Jan 1. doi: 10.7150/thno.46360

PMCID:: PMC7681085

Article PDF–4.4M

Select item 748143118.

Targeted inhibition of KDM6 histone demethylases eradicates tumor-initiating cells via enhancer reprogramming in colorectal cancer

Junbao Zhang, Ying Ying, Meiqi Li, Maolin Wang, Xiaoyan Huang, Min Jia, Junhui Zeng, Canjie Ma, Yixiang Zhang, Chen Li, Xiaomei Wang, Xing-sheng Shu

Theranostics. 2020; 10(22): 10016–10030. Published online 2020 Aug 8. doi: 10.7150/thno.47081

PMCID:: PMC7481431

Article PDF–3.2M

Select item 721658319.

Two old drugs, NVP-AEW541 and GSK-J4, repurposed against the Toxoplasma gondii RH strain

Shuxian Liu, Mimi Wu, Qianqian Hua, Daiqiang Lu, Yuan Tian, Helin Yu, Linyan Cheng, Yinqi Chen, Jiaxin Cao, Xin Hu, Feng Tan

Parasit Vectors. 2020; 13: 242. Published online 2020 May 11. doi: 10.1186/s13071-020-04094-2

PMCID:: PMC7216583

Article PDF–2.1M

Select item 716065720.

The IUPHAR Guide to Immunopharmacology: connecting immunology and pharmacology

Simon D. Harding, Elena Faccenda, Christopher Southan, Adam J. Pawson, Pasquale Maffia, Stephen P. H. Alexander, Anthony P. Davenport, Doriano Fabbro, Francesca Levi‐Schaffer, Michael Spedding, Jamie A. Davies

Immunology. 2020 May; 160(1): 10–23. Published online 2020 Mar 2. doi: 10.1111/imm.13175