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Select item 49377981.

Cytokine and autoantibody patterns in acute liver failure

Jinze Li, Xu Zhu, Feng Liu, Ping Cai, Corron Sanders, William M. Lee, Jack Uetrecht

J Immunotoxicol. Author manuscript; available in PMC 2016 Jul 8.

Published in final edited form as: J Immunotoxicol. 2010 Jul-Sep; 7(3): 157–164. doi: 10.3109/15476910903501748

PMCID:: PMC4937798

Abstract Article PDF–2.0M

Select item 49319042.

What factors determine the severity of hepatitis A-related acute liver failure?

V. Ajmera, G. Xia, G. Vaughan, J. C. Forbi, L. M. Ganova-Raeva, Y. Khudyakov, C. K. Opio, R. Taylor, R. Restrepo, S. Munoz, R. J. Fontana, W. M. Lee, the Acute Liver Failure Study Group

J Viral Hepat. Author manuscript; available in PMC 2016 Jul 4.

Published in final edited form as: J Viral Hepat. 2011 Jul; 18(7): e167–e174. Published online 2010 Dec 8. doi: 10.1111/j.1365-2893.2010.01410.x

PMCID:: PMC4931904

Abstract Article PDF–403K

Select item 49073483.

Prenatal and infant acetaminophen exposure, antioxidant gene polymorphisms and childhood asthma

Seif O Shaheen, Roger B Newson, Susan M Ring, Matthew J Rose-Zerilli, John W Holloway, A John Henderson

J Allergy Clin Immunol. Author manuscript; available in PMC 2016 Jun 14.

Published in final edited form as: J Allergy Clin Immunol. 2010 Dec; 126(6): 1141–8.e7. Published online 2010 Nov 4. doi: 10.1016/j.jaci.2010.08.047

PMCID:: PMC4907348

Abstract Article PDF–105K

Select item 48583874.

Effects of Acetaminophen on Oxidant and Irritant Respiratory Tract Responses to Environmental Tobacco Smoke in Female Mice

Gregory J. Smith, Joseph A. Cichocki, Bennett J. Doughty, Jose E. Manautou, Sven-Eric Jordt, John B. Morris

Environ Health Perspect. 2016 May; 124(5): 642–650. Published online 2015 Oct 9. doi: 10.1289/ehp.1509851

PMCID:: PMC4858387

Abstract Article PDF–377K

Select item 48308935.

Interindividual variation in gene expression responses and metabolite formation in acetaminophen-exposed primary human hepatocytes

Marlon J. A. Jetten, Ainhoa Ruiz-Aracama, Maarten L. J. Coonen, Sandra M. Claessen, Marcel H. M. van Herwijnen, Arjen Lommen, Joost H. M. van Delft, Ad A. C. M. Peijnenburg, Jos C. S. Kleinjans

Arch Toxicol. 2016; 90: 1103–1115. Published online 2015 Jun 24. doi: 10.1007/s00204-015-1545-2

PMCID:: PMC4830893

Abstract Article PDF–1.6M

Select item 46995856.

Analysis of N¹-acetyl-N²-formyl-5-methoxykynuramine/N¹-acetyl-5-methoxy-kynuramine formation from melatonin in mice

Sida Niu, Feng Li, Dun-Xian Tan, Lirong Zhang, Jeffrey R. Idle, Frank J. Gonzalez, Xiaochao Ma

J Pineal Res. Author manuscript; available in PMC 2016 Jan 4.

Published in final edited form as: J Pineal Res. 2010 Sep; 49(2): 106–114. Published online 2010 May 27. doi: 10.1111/j.1600-079X.2010.00771.x

PMCID:: PMC4699585

Abstract Article PDF–651K

Select item 46760727.

Pharmacogenetic selection of transplanted human hepatocytes in immunocompetent rats

Martina SMOLIC, Catherine H. WU, Shilpa MADADI, Nidhi GUPTA, Robert SMOLIC, Marcy COASH, Jeanette SMIT, George Y. WU

J Dig Dis. Author manuscript; available in PMC 2015 Dec 11.

Published in final edited form as: J Dig Dis. 2012 Nov; 13(11): 579–587. doi: 10.1111/j.1751-2980.2012.00632.x

PMCID:: PMC4676072

Abstract Article PDF–521K

Select item 46753518.

Role of Biotransformation in Drug-Induced Toxicity: Influence of Intra- and Inter-Species Differences in Drug Metabolism

Thomas A. Baillie, Allan E. Rettie

Drug Metab Pharmacokinet. Author manuscript; available in PMC 2015 Dec 10.

Published in final edited form as: Drug Metab Pharmacokinet. 2011; 26(1): 15–29. Published online 2010 Oct 22. doi: 10.2133/dmpk.dmpk-10-rv-089

PMCID:: PMC4675351

Abstract Article PDF–1.6M

Select item 46262379.

Predose and Postdose Blood Gene Expression Profiles Identify the Individuals Susceptible to Acetaminophen-Induced Liver Injury in Rats

Xiaoyan Lu, Bin Hu, Jie Zheng, Cai Ji, Xiaohui Fan, Yue Gao

PLoS One. 2015; 10(10): e0141750. Published online 2015 Oct 29. doi: 10.1371/journal.pone.0141750

PMCID:: PMC4626237

Abstract Article PDF–1.3M

Select item 462277410.

Hyperammonemia, brain edema and blood-brain barrier alterations in prehepatic portal hypertensive rats and paracetamol intoxication

Camila Scorticati, Juan P Prestifilippo, Francisco X Eizayaga, José L Castro, Salvador Romay, María A Fernández, Abraham Lemberg, Juan C Perazzo

World J Gastroenterol. 2004 May 1; 10(9): 1321–1324. Published online 2004 May 1. doi: 10.3748/wjg.v10.i9.1321

PMCID:: PMC4622774

Abstract Article PDF–170K

Select item 461130611.

Imatinib-induced fatal acute liver failure

Ezequiel Ridruejo, Roberto Cacchione, Alejandra G Villamil, Sebastián Marciano, Adrián C Gadano, Oscar G Mandó

World J Gastroenterol. 2007 Dec 28; 13(48): 6608–6611. Published online 2007 Dec 28. doi: 10.3748/wjg.v13.i48.6608

PMCID:: PMC4611306

Abstract Article PDF–487K

Select item 454006112.

N-acetylcysteine - a safe antidote for cysteine/glutathione deficiency

Kondala R. Atkuri, John J. Mantovani, Leonard A. Herzenberg, Leonore A. Herzenberg

Curr Opin Pharmacol. Author manuscript; available in PMC 2015 Aug 18.

Published in final edited form as: Curr Opin Pharmacol. 2007 Aug; 7(4): 355–359. Published online 2007 Jun 29. doi: 10.1016/j.coph.2007.04.005

PMCID:: PMC4540061

Abstract Article PDF–113K

Select item 453192413.

Protective Effect of Chlormethiazole, a Sedative, against Acetaminophen-Induced Liver Injury in Mice

Han Chu Lee, Sung Ae Jung, Hye Kyung Jung, Sun Young Yi, Doe Young Kim, Il Hwan Moon, Sung Su Park

Korean J Intern Med. 1999 Jul; 14(2): 27–33. doi: 10.3904/kjim.1999.14.2.27

PMCID:: PMC4531924

Abstract Article PDF–154K

Select item 445413214.

p53 Contributes to Differentiating Gene Expression Following Exposure to Acetaminophen and Its Less Hepatotoxic Regioisomer Both In Vitro and In Vivo

Brendan D Stamper, Michael L Garcia, Duy Q Nguyen, Richard P Beyer, Theo K Bammler, Frederico M Farin, Terrance J Kavanagh, Sidney D Nelson

Gene Regul Syst Bio. 2015; 9: 1–14. Published online 2015 Jun 1. doi: 10.4137/GRSB.S25388

PMCID:: PMC4454132

Abstract Article PDF–1.4M

Select item 442832815.

Differential Fmo3 Gene Expression in Various Liver Injury Models Involving Hepatic Oxidative Stress in Mice

Swetha Rudraiah, Jamie E. Moscovitz, Ajay C. Donepudi, Sarah N. Campion, Angela L. Slitt, Lauren M. Aleksunes, José E. Manautou

Toxicology. Author manuscript; available in PMC 2015 Nov 5.

Published in final edited form as: Toxicology. 2014 Nov 5; 325: 85–95. Published online 2014 Sep 2. doi: 10.1016/j.tox.2014.08.013

PMCID:: PMC4428328

Abstract Article PDF–3.9M

Select item 442210516.

Identification of chemical modulators of the constitutive activated receptor (CAR) in a gene expression compendium

Keiyu Oshida, Naresh Vasani, Carlton Jones, Tanya Moore, Susan Hester, Stephen Nesnow, Scott Auerbach, David R. Geter, Lauren M. Aleksunes, Russell S. Thomas, Dawn Applegate, Curtis D. Klaassen, J. Christopher Corton

Nucl Recept Signal. 2015; 13: e002. Published online 2015 Apr 27. doi: 10.1621/nrs.13002

PMCID:: PMC4422105

Abstract Article PDF–6.9M

Select item 440925517.

Chronic Deletion and Acute Knockdown of Parkin Have Differential Responses to Acetaminophen-induced Mitophagy and Liver Injury in Mice

Jessica A. Williams, Hong-Min Ni, Anna Haynes, Sharon Manley, Yuan Li, Hartmut Jaeschke, Wen-Xing Ding

J Biol Chem. 2015 Apr 24; 290(17): 10934–10946. Published online 2015 Mar 9. doi: 10.1074/jbc.M114.602284

PMCID:: PMC4409255

Abstract Article PDF–2.4M

Select item 439865618.

Hepatitis C Virus Structural Proteins can Exacerbate or Ameliorate Acetaminophen-induced Liver Injury in Mice

Anup Ramachandran, Margitta Lebofsky, Hui-Min Yan, Steven A. Weinman, Hartmut Jaeschke

Arch Toxicol. Author manuscript; available in PMC 2016 May 1.

Published in final edited form as: Arch Toxicol. 2015 May; 89(5): 773–783. Published online 2015 Mar 6. doi: 10.1007/s00204-015-1498-5

PMCID:: PMC4398656

Abstract Article PDF–3.5M

Select item 437664419.

Saikosaponin d protects against acetaminophen-induced hepatotoxicity by inhibiting NFκB and STAT3 signaling

Aiming Liu, Naoki Tanaka, Lu Sun, Bin Guo, Jung-Hwan Kim, Kristopher W. Krausz, Zhong-Ze Fang, Changtao Jiang, Julin Yang, Frank J. Gonzalez

Chem Biol Interact. Author manuscript; available in PMC 2016 Mar 27.

Published in final edited form as: Chem Biol Interact. 2014 Nov 5; 223: 80–86. Published online 2014 Sep 27. doi: 10.1016/j.cbi.2014.09.012

PMCID:: PMC4376644

Abstract Article PDF–762K

Select item 434914120.

MicroRNA-122: A Novel Hepatocyte-Enriched in vitro Marker of Drug-Induced Cellular Toxicity

Richard Kia, Lorna Kelly, Rowena L. C. Sison-Young, Fang Zhang, Chris S. Pridgeon, James A. Heslop, Pete Metcalfe, Neil R. Kitteringham, Melissa Baxter, Sean Harrison, Neil A. Hanley, Zoë D. Burke, Mike P. Storm, Melanie J. Welham, David Tosh, Barbara Küppers-Munther, Josefina Edsbagge, Philip J. Starkey Lewis, Frank Bonner, Ernie Harpur, James Sidaway, Joanne Bowes, Stephen W. Fenwick, Hassan Malik, Chris E. P. Goldring, B. Kevin Park

Toxicol Sci. 2015 Mar; 144(1): 173–185. Published online 2014 Dec 18. doi: 10.1093/toxsci/kfu269

PMCID:: PMC4349141

Abstract Article PDF–871K

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