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Select item 40962021.

A Novel BHLHE41 Variant is Associated with Short Sleep and Resistance to Sleep Deprivation in Humans

Renata Pellegrino, Ibrahim Halil Kavakli, Namni Goel, Christopher J. Cardinale, David F. Dinges, Samuel T. Kuna, Greg Maislin, Hans P.A. Van Dongen, Sergio Tufik, John B. Hogenesch, Hakon Hakonarson, Allan I. Pack

Sleep. 2014 Aug 1; 37(8): 1327–1336. Published online 2014 Aug 1. doi: 10.5665/sleep.3924

Correction in:: Sleep. 2015 Nov 1; 38(11): 1827.

PMCID:: PMC4096202

Article PDF–1.1M

Select item 31213902.

Down-modulation of the G-protein-coupled Estrogen Receptor, GPER, from the Cell Surface Occurs via a trans-Golgi-Proteasome Pathway

Shi-Bin Cheng, Jeffrey A. Quinn, Carl T. Graeber, Edward J. Filardo

J Biol Chem. 2011 Jun 24; 286(25): 22441–22455. Published online 2011 May 2. doi: 10.1074/jbc.M111.224071

PMCID:: PMC3121390

Article PDF–5.0M

Select item 3791213.

A Polymorphism in the β1 Adrenergic Receptor Is Associated with Resting Heart Rate

Koustubh Ranade, Eric Jorgenson, Wayne H.-H. Sheu, Dee Pei, Chao Agnes Hsiung, Fu-tien Chiang, Yii-der I. Chen, Richard Pratt, Richard A. Olshen, David Curb, David R. Cox, David Botstein, Neil Risch

Am J Hum Genet. 2002 Apr; 70(4): 935–942. Published online 2002 Feb 18. doi: 10.1086/339621

PMCID:: PMC379121

Article PDF–110K

Select item 2994474.

Cloning of the cDNA for the human beta 1-adrenergic receptor.

T Frielle, S Collins, K W Daniel, M G Caron, R J Lefkowitz, B K Kobilka

Proc Natl Acad Sci U S A. 1987 Nov; 84(22): 7920–7924. doi: 10.1073/pnas.84.22.7920

PMCID:: PMC299447

Summary Page Browse PDF–1.4M

Select item 1347195.

Direct Binding of the β1 Adrenergic Receptor to the Cyclic AMP-Dependent Guanine Nucleotide Exchange Factor CNrasGEF Leads to Ras Activation

Youngshil Pak, Nam Pham, Daniela Rotin

Mol Cell Biol. 2002 Nov; 22(22): 7942–7952. doi: 10.1128/MCB.22.22.7942-7952.2002

PMCID:: PMC134719

Article PDF–582K

Select item 69497356.

Network Pharmacology-Based Investigation into the Mechanisms of Quyushengxin Formula for the Treatment of Ulcerative Colitis

Haojie Yang, Ying Li, Sichen Shen, Dan Gan, Changpeng Han, Jiong Wu, Zhenyi Wang

Evid Based Complement Alternat Med. 2019; 2019: 7870424. Published online 2019 Dec 20. doi: 10.1155/2019/7870424

PMCID:: PMC6949735

Article PDF–1.2M

Select item 68323867.

Drug Side-Effect Prediction Via Random Walk on the Signed Heterogeneous Drug Network

Baofang Hu, Hong Wang, Zhenmei Yu

Molecules. 2019 Oct; 24(20): 3668. Published online 2019 Oct 11. doi: 10.3390/molecules24203668

PMCID:: PMC6832386

Article PDF–2.3M

Select item 67597968.

Integrating Pharmacokinetics Study, Network Analysis, and Experimental Validation to Uncover the Mechanism of Qiliqiangxin Capsule Against Chronic Heart Failure

Yu Zhang, Mingdan Zhu, Fugeng Zhang, Shaoqiang Zhang, Wuxun Du, Xuefeng Xiao

Front Pharmacol. 2019; 10: 1046. Published online 2019 Sep 18. doi: 10.3389/fphar.2019.01046

PMCID:: PMC6759796

Article PDF–2.4M

Select item 65299279.

Human leukocyte antigen associations in postural tachycardia syndrome

Yong‐Won Shin, Jangsup Moon, Tae‐Joon Kim, Do‐Yong Kim, Hyeyeon Chang, Jin‐Sun Jun, Soon‐Tae Lee, Keun‐Hwa Jung, Kyung‐Il Park, Ki‐Young Jung, Manho Kim, Sang Kun Lee, Kon Chu

Ann Clin Transl Neurol. 2019 May; 6(5): 962–967. Published online 2019 Apr 4. doi: 10.1002/acn3.766

PMCID:: PMC6529927

Article PDF–1.0M

Select item 619237510.

Comparison of Quantitative and Qualitative (Q)SAR Models Created for the Prediction of K_i and IC₅₀ Values of Antitarget Inhibitors

Alexey A. Lagunin, Maria A. Romanova, Anton D. Zadorozhny, Natalia S. Kurilenko, Boris V. Shilov, Pavel V. Pogodin, Sergey M. Ivanov, Dmitry A. Filimonov, Vladimir V. Poroikov

Front Pharmacol. 2018; 9: 1136. Published online 2018 Oct 10. doi: 10.3389/fphar.2018.01136

PMCID:: PMC6192375

Article PDF–1.6M

Select item 608776411.

System Pharmacology-Based Strategy to Decode the Synergistic Mechanism of Zhi-zhu Wan for Functional Dyspepsia

Chun Wang, Qing Ren, Xue-Tong Chen, Zhi-Qian Song, Zhang-Chi Ning, Jia-He Gan, Xin-Ling Ma, Dong-Rui Liang, Dao-Gang Guan, Zhen-Li Liu, Ai-Ping Lu

Front Pharmacol. 2018; 9: 841. Published online 2018 Aug 6. doi: 10.3389/fphar.2018.00841

PMCID:: PMC6087764

Article PDF–4.7M

Select item 599114212.

Degenerate Suppression PCR Identifies the β₂-Adrenergic Receptor as Upregulated by Neuronal Differentiation

Jan Lewerenz, Frank Leypoldt, Axel Methner

Gene Expr. 2003; 11(2): 105–116. Published online 2018 Jun 7. doi: 10.3727/000000003108749008

PMCID:: PMC5991142

Article PDF–429K

Select item 598520913.

Protein lipidation: Occurrence, mechanisms, biological functions, and enabling technologies

Hong Jiang, Xiaoyu Zhang, Xiao Chen, Pornpun Aramsangtienchai, Zhen Tong, Hening Lin

Chem Rev. Author manuscript; available in PMC 2019 Feb 14.

Published in final edited form as: Chem Rev. 2018 Feb 14; 118(3): 919–988. Published online 2018 Jan 2. doi: 10.1021/acs.chemrev.6b00750

PMCID:: PMC5985209

Article PDF–5.5M

Select item 577035414.

An automated framework for QSAR model building

Samina Kausar, Andre O. Falcao

J Cheminform. 2018; 10: 1. Published online 2018 Jan 16. doi: 10.1186/s13321-017-0256-5

PMCID:: PMC5770354

Article PDF–2.0M

Select item 574290715.

New Targets for Zika Virus Determined by Human-Viral Interactomic: A Bioinformatics Approach

Eduardo Esteves, Nuno Rosa, Maria José Correia, Joel P. Arrais, Marlene Barros

Biomed Res Int. 2017; 2017: 1734151. Published online 2017 Dec 12. doi: 10.1155/2017/1734151

PMCID:: PMC5742907

Article PDF–1.6M

Select item 568209616.

Systems Pharmacological Approach to the Effect of Bulsu-san Promoting Parturition

Su Yeon Suh, Won G. An

Evid Based Complement Alternat Med. 2017; 2017: 7236436. Published online 2017 Oct 29. doi: 10.1155/2017/7236436

PMCID:: PMC5682096

Article PDF–1.2M

Select item 565066717.

THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: G protein‐coupled receptors

Stephen PH Alexander, Arthur Christopoulos, Anthony P Davenport, Eamonn Kelly, Neil V Marrion, John A Peters, Elena Faccenda, Simon D Harding, Adam J Pawson, Joanna L Sharman, Christopher Southan, Jamie A Davies, CGTP Collaborators

Br J Pharmacol. 2017 Dec; 174(Suppl Suppl 1): S17–S129. Published online 2017 Oct 21. doi: 10.1111/bph.13878