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dbSNP Short Genetic Variations

Welcome to the Reference SNP (rs) Report

All alleles are reported in the Forward orientation. Click on the Variant Details tab for details on Genomic Placement, Gene, and Amino Acid changes. HGVS names are in the HGVS tab.

Reference SNP (rs) Report

This page reports data for a single dbSNP Reference SNP variation (RefSNP or rs) from the new redesigned dbSNP build.
Top of the page reports a concise summary for the rs, with more specific details included in the corresponding tabs below.
All alleles are reported in the Forward orientation. Use the Genomic View to inspect the nucleotides flanking the variant, and its neighbors.
For more information see Help documentation.

rs10505476

Current Build 156

Released September 21, 2022

Organism
Homo sapiens
Position
chr8:127395871 (GRCh38.p14) Help

The anchor position for this RefSNP. Includes all nucleotides potentially affected by this change, thus it can differ from HGVS, which is right-shifted. See here for details.

Alleles
C>T
Variation Type
SNV Single Nucleotide Variation
Frequency
T=0.373966 (98985/264690, TOPMED)
T=0.268803 (60971/226824, ALFA)
T=0.380266 (53241/140010, GnomAD) (+ 21 more)
T=0.18720 (5290/28258, 14KJPN)
T=0.19147 (3209/16760, 8.3KJPN)
T=0.3462 (2217/6404, 1000G_30x)
T=0.3419 (1712/5008, 1000G)
T=0.2692 (1206/4480, Estonian)
T=0.2696 (1039/3854, ALSPAC)
T=0.2562 (950/3708, TWINSUK)
T=0.2423 (710/2930, KOREAN)
T=0.2702 (563/2084, HGDP_Stanford)
T=0.4249 (803/1890, HapMap)
T=0.2353 (431/1832, Korea1K)
T=0.2496 (282/1130, Daghestan)
T=0.283 (282/998, GoNL)
T=0.234 (185/792, PRJEB37584)
T=0.348 (209/600, NorthernSweden)
C=0.361 (88/244, SGDP_PRJ)
T=0.296 (64/216, Qatari)
T=0.196 (42/214, Vietnamese)
T=0.23 (22/94, Ancient Sardinia)
T=0.42 (17/40, GENOME_DK)
C=0.36 (10/28, Siberian)
Clinical Significance
Not Reported in ClinVar
Gene : Consequence
CASC8 : Intron Variant
Publications
8 citations
Genomic View
See rs on genome

ALFA Allele Frequency
The ALFA project provide aggregate allele frequency from dbGaP. More information is available on the project page including descriptions, data access, and terms of use.

Release Version: 20230706150541
Population Group Sample Size Ref Allele Alt Allele
Total Global 226824 C=0.731197 T=0.268803
European Sub 193028 C=0.744742 T=0.255258
African Sub 10380 C=0.34480 T=0.65520
African Others Sub 360 C=0.247 T=0.753
African American Sub 10020 C=0.34830 T=0.65170
Asian Sub 786 C=0.793 T=0.207
East Asian Sub 616 C=0.787 T=0.213
Other Asian Sub 170 C=0.812 T=0.188
Latin American 1 Sub 982 C=0.623 T=0.377
Latin American 2 Sub 9008 C=0.8509 T=0.1491
South Asian Sub 5056 C=0.8289 T=0.1711
Other Sub 7584 C=0.7156 T=0.2844


Help

Frequency tab displays a table of the reference and alternate allele frequencies reported by various studies and populations. Table lines, where Population="Global" refer to the entire study population, whereas lines, where Group="Sub", refer to a study-specific population subgroupings (i.e. AFR, CAU, etc.), if available. Frequency for the alternate allele (Alt Allele) is a ratio of samples observed-to-total, where the numerator (observed samples) is the number of chromosomes in the study with the minor allele present (found in "Sample size", where Group="Sub"), and the denominator (total samples) is the total number of all chromosomes in the study for the variant (found in "Sample size", where Group="Study-wide" and Population="Global").

Download
Study Population Group Sample Size Ref Allele Alt Allele
TopMed Global Study-wide 264690 C=0.626034 T=0.373966
Allele Frequency Aggregator Total Global 226824 C=0.731197 T=0.268803
Allele Frequency Aggregator European Sub 193028 C=0.744742 T=0.255258
Allele Frequency Aggregator African Sub 10380 C=0.34480 T=0.65520
Allele Frequency Aggregator Latin American 2 Sub 9008 C=0.8509 T=0.1491
Allele Frequency Aggregator Other Sub 7584 C=0.7156 T=0.2844
Allele Frequency Aggregator South Asian Sub 5056 C=0.8289 T=0.1711
Allele Frequency Aggregator Latin American 1 Sub 982 C=0.623 T=0.377
Allele Frequency Aggregator Asian Sub 786 C=0.793 T=0.207
gnomAD - Genomes Global Study-wide 140010 C=0.619734 T=0.380266
gnomAD - Genomes European Sub 75832 C=0.73516 T=0.26484
gnomAD - Genomes African Sub 41944 C=0.33476 T=0.66524
gnomAD - Genomes American Sub 13636 C=0.79173 T=0.20827
gnomAD - Genomes Ashkenazi Jewish Sub 3316 C=0.6951 T=0.3049
gnomAD - Genomes East Asian Sub 3128 C=0.7871 T=0.2129
gnomAD - Genomes Other Sub 2154 C=0.6574 T=0.3426
14KJPN JAPANESE Study-wide 28258 C=0.81280 T=0.18720
8.3KJPN JAPANESE Study-wide 16760 C=0.80853 T=0.19147
1000Genomes_30x Global Study-wide 6404 C=0.6538 T=0.3462
1000Genomes_30x African Sub 1786 C=0.2699 T=0.7301
1000Genomes_30x Europe Sub 1266 C=0.7480 T=0.2520
1000Genomes_30x South Asian Sub 1202 C=0.8486 T=0.1514
1000Genomes_30x East Asian Sub 1170 C=0.8085 T=0.1915
1000Genomes_30x American Sub 980 C=0.808 T=0.192
1000Genomes Global Study-wide 5008 C=0.6581 T=0.3419
1000Genomes African Sub 1322 C=0.2678 T=0.7322
1000Genomes East Asian Sub 1008 C=0.8065 T=0.1935
1000Genomes Europe Sub 1006 C=0.7396 T=0.2604
1000Genomes South Asian Sub 978 C=0.840 T=0.160
1000Genomes American Sub 694 C=0.811 T=0.189
Genetic variation in the Estonian population Estonian Study-wide 4480 C=0.7308 T=0.2692
The Avon Longitudinal Study of Parents and Children PARENT AND CHILD COHORT Study-wide 3854 C=0.7304 T=0.2696
UK 10K study - Twins TWIN COHORT Study-wide 3708 C=0.7438 T=0.2562
KOREAN population from KRGDB KOREAN Study-wide 2930 C=0.7577 T=0.2423
HGDP-CEPH-db Supplement 1 Global Study-wide 2084 C=0.7298 T=0.2702
HGDP-CEPH-db Supplement 1 Est_Asia Sub 470 C=0.764 T=0.236
HGDP-CEPH-db Supplement 1 Central_South_Asia Sub 414 C=0.790 T=0.210
HGDP-CEPH-db Supplement 1 Middle_Est Sub 350 C=0.677 T=0.323
HGDP-CEPH-db Supplement 1 Europe Sub 320 C=0.787 T=0.212
HGDP-CEPH-db Supplement 1 Africa Sub 242 C=0.248 T=0.752
HGDP-CEPH-db Supplement 1 America Sub 216 C=0.991 T=0.009
HGDP-CEPH-db Supplement 1 Oceania Sub 72 C=1.00 T=0.00
HapMap Global Study-wide 1890 C=0.5751 T=0.4249
HapMap American Sub 768 C=0.727 T=0.273
HapMap African Sub 692 C=0.266 T=0.734
HapMap Asian Sub 254 C=0.827 T=0.173
HapMap Europe Sub 176 C=0.767 T=0.233
Korean Genome Project KOREAN Study-wide 1832 C=0.7647 T=0.2353
Genome-wide autozygosity in Daghestan Global Study-wide 1130 C=0.7504 T=0.2496
Genome-wide autozygosity in Daghestan Daghestan Sub 624 C=0.777 T=0.223
Genome-wide autozygosity in Daghestan Near_East Sub 144 C=0.646 T=0.354
Genome-wide autozygosity in Daghestan Central Asia Sub 122 C=0.754 T=0.246
Genome-wide autozygosity in Daghestan Europe Sub 108 C=0.713 T=0.287
Genome-wide autozygosity in Daghestan South Asian Sub 96 C=0.82 T=0.18
Genome-wide autozygosity in Daghestan Caucasus Sub 36 C=0.61 T=0.39
Genome of the Netherlands Release 5 Genome of the Netherlands Study-wide 998 C=0.717 T=0.283
CNV burdens in cranial meningiomas Global Study-wide 792 C=0.766 T=0.234
CNV burdens in cranial meningiomas CRM Sub 792 C=0.766 T=0.234
Northern Sweden ACPOP Study-wide 600 C=0.652 T=0.348
SGDP_PRJ Global Study-wide 244 C=0.361 T=0.639
Qatari Global Study-wide 216 C=0.704 T=0.296
A Vietnamese Genetic Variation Database Global Study-wide 214 C=0.804 T=0.196
Ancient Sardinia genome-wide 1240k capture data generation and analysis Global Study-wide 94 C=0.77 T=0.23
The Danish reference pan genome Danish Study-wide 40 C=0.57 T=0.42
Siberian Global Study-wide 28 C=0.36 T=0.64
Help

Variant Details tab shows known variant placements on genomic sequences: chromosomes (NC_), RefSeqGene, pseudogenes or genomic regions (NG_), and in a separate table: on transcripts (NM_) and protein sequences (NP_). The corresponding transcript and protein locations are listed in adjacent lines, along with molecular consequences from Sequence Ontology. When no protein placement is available, only the transcript is listed. Column "Codon[Amino acid]" shows the actual base change in the format of "Reference > Alternate" allele, including the nucleotide codon change in transcripts, and the amino acid change in proteins, respectively, allowing for known ribosomal slippage sites. To view nucleotides adjacent to the variant use the Genomic View at the bottom of the page - zoom into the sequence until the nucleotides around the variant become visible.

Genomic Placements
Sequence name Change
GRCh38.p14 chr 8 NC_000008.11:g.127395871C>T
GRCh37.p13 chr 8 NC_000008.10:g.128408116C>T
Gene: CASC8, cancer susceptibility 8 (minus strand)
Molecule type Change Amino acid[Codon] SO Term
CASC8 transcript variant 1 NR_117100.1:n. N/A Intron Variant
CASC8 transcript variant 2 NR_024393.1:n. N/A Genic Downstream Transcript Variant
Help

Clinical Significance tab shows a list of clinical significance entries from ClinVar associated with the variation, per allele. Click on the RCV accession (i.e. RCV000001615.2) or Allele ID (i.e. 12274) to access full ClinVar report.

Not Reported in ClinVar
Help

Aliases tab displays HGVS names representing the variant placements and allele changes on genomic, transcript and protein sequences, per allele. HGVS name is an expression for reporting sequence accession and version, sequence type, position, and allele change. The column "Note" can have two values: "diff" means that there is a difference between the reference allele (variation interval) at the placement reported in HGVS name and the reference alleles reported in other HGVS names, and "rev" means that the sequence of this variation interval at the placement reported in HGVS name is in reverse orientation to the sequence(s) of this variation in other HGVS names not labeled as "rev".

Placement C= T
GRCh38.p14 chr 8 NC_000008.11:g.127395871= NC_000008.11:g.127395871C>T
GRCh37.p13 chr 8 NC_000008.10:g.128408116= NC_000008.10:g.128408116C>T
Help

Submissions tab displays variations originally submitted to dbSNP, now supporting this RefSNP cluster (rs). We display Submitter handle, Submission identifier, Date and Build number, when the submission appeared for the first time. Direct submissions to dbSNP have Submission ID in the form of an ss-prefixed number (ss#). Other supporting variations are listed in the table without ss#.

130 SubSNP, 24 Frequency submissions
No Submitter Submission ID Date (Build)
1 PERLEGEN ss14900174 Dec 05, 2003 (119)
2 SSAHASNP ss22656422 Apr 05, 2004 (121)
3 PERLEGEN ss24546178 Sep 20, 2004 (123)
4 ABI ss44847578 Mar 13, 2006 (126)
5 AFFY ss66032148 Dec 01, 2006 (127)
6 ILLUMINA ss66730519 Dec 01, 2006 (127)
7 ILLUMINA ss66891013 Dec 01, 2006 (127)
8 ILLUMINA ss66994680 Dec 01, 2006 (127)
9 PERLEGEN ss69062064 May 17, 2007 (127)
10 ILLUMINA ss70372184 May 17, 2007 (127)
11 ILLUMINA ss70486966 May 23, 2008 (130)
12 ILLUMINA ss71011212 May 17, 2007 (127)
13 ILLUMINA ss75691759 Dec 06, 2007 (129)
14 AFFY ss76422534 Dec 08, 2007 (130)
15 HGSV ss84035942 Dec 14, 2007 (130)
16 KRIBB_YJKIM ss84964632 Dec 14, 2007 (130)
17 HGSV ss85514096 Dec 14, 2007 (130)
18 HUMANGENOME_JCVI ss97902679 Feb 03, 2009 (130)
19 SNP500CANCER ss105437235 Feb 03, 2009 (130)
20 1000GENOMES ss108389966 Jan 23, 2009 (130)
21 1000GENOMES ss113758869 Jan 25, 2009 (130)
22 ILLUMINA-UK ss116186732 Feb 14, 2009 (130)
23 SNP500CANCER ss120035141 Dec 01, 2009 (131)
24 ILLUMINA ss121343926 Dec 01, 2009 (131)
25 ENSEMBL ss134527242 Dec 01, 2009 (131)
26 ILLUMINA ss152768183 Dec 01, 2009 (131)
27 GMI ss156881649 Dec 01, 2009 (131)
28 ILLUMINA ss159131881 Dec 01, 2009 (131)
29 ILLUMINA ss159904878 Dec 01, 2009 (131)
30 COMPLETE_GENOMICS ss162786877 Jul 04, 2010 (132)
31 COMPLETE_GENOMICS ss165717401 Jul 04, 2010 (132)
32 COMPLETE_GENOMICS ss167127078 Jul 04, 2010 (132)
33 ILLUMINA ss169492218 Jul 04, 2010 (132)
34 ILLUMINA ss170267259 Jul 04, 2010 (132)
35 BUSHMAN ss199771211 Jul 04, 2010 (132)
36 1000GENOMES ss223978720 Jul 14, 2010 (132)
37 1000GENOMES ss234627304 Jul 15, 2010 (132)
38 1000GENOMES ss241441345 Jul 15, 2010 (132)
39 GMI ss280003843 May 04, 2012 (137)
40 PJP ss294183425 May 09, 2011 (134)
41 ILLUMINA ss479300540 May 04, 2012 (137)
42 ILLUMINA ss479303694 May 04, 2012 (137)
43 ILLUMINA ss479685376 Sep 08, 2015 (146)
44 ILLUMINA ss484450689 May 04, 2012 (137)
45 ILLUMINA ss536617383 Sep 08, 2015 (146)
46 TISHKOFF ss561069609 Apr 25, 2013 (138)
47 SSMP ss655503991 Apr 25, 2013 (138)
48 ILLUMINA ss778734962 Sep 08, 2015 (146)
49 ILLUMINA ss782671879 Aug 21, 2014 (142)
50 ILLUMINA ss783640585 Sep 08, 2015 (146)
51 ILLUMINA ss825341795 Apr 01, 2015 (144)
52 ILLUMINA ss831922555 Apr 01, 2015 (144)
53 ILLUMINA ss832644565 Aug 21, 2014 (142)
54 ILLUMINA ss833235254 Aug 21, 2014 (142)
55 ILLUMINA ss834194492 Sep 08, 2015 (146)
56 EVA-GONL ss986056377 Aug 21, 2014 (142)
57 JMKIDD_LAB ss1075916669 Aug 21, 2014 (142)
58 1000GENOMES ss1331909761 Aug 21, 2014 (142)
59 HAMMER_LAB ss1397539577 Sep 08, 2015 (146)
60 DDI ss1431670535 Apr 01, 2015 (144)
61 EVA_GENOME_DK ss1582885422 Apr 01, 2015 (144)
62 EVA_DECODE ss1595672723 Apr 01, 2015 (144)
63 EVA_UK10K_ALSPAC ss1621728517 Apr 01, 2015 (144)
64 EVA_UK10K_TWINSUK ss1664722550 Apr 01, 2015 (144)
65 EVA_SVP ss1713070953 Apr 01, 2015 (144)
66 ILLUMINA ss1752712076 Sep 08, 2015 (146)
67 HAMMER_LAB ss1805761049 Sep 08, 2015 (146)
68 WEILL_CORNELL_DGM ss1929329340 Feb 12, 2016 (147)
69 JJLAB ss2025368142 Sep 14, 2016 (149)
70 ILLUMINA ss2095215273 Dec 20, 2016 (150)
71 USC_VALOUEV ss2153596807 Dec 20, 2016 (150)
72 HUMAN_LONGEVITY ss2307374107 Dec 20, 2016 (150)
73 SYSTEMSBIOZJU ss2627158916 Nov 08, 2017 (151)
74 ILLUMINA ss2634803770 Nov 08, 2017 (151)
75 ILLUMINA ss2634803771 Nov 08, 2017 (151)
76 ILLUMINA ss2635188360 Nov 08, 2017 (151)
77 GRF ss2709383762 Nov 08, 2017 (151)
78 ILLUMINA ss2711149505 Nov 08, 2017 (151)
79 GNOMAD ss2872694478 Nov 08, 2017 (151)
80 SWEGEN ss3003997383 Nov 08, 2017 (151)
81 BIOINF_KMB_FNS_UNIBA ss3026469695 Nov 08, 2017 (151)
82 CSHL ss3348404625 Nov 08, 2017 (151)
83 ILLUMINA ss3630158658 Oct 12, 2018 (152)
84 ILLUMINA ss3632699941 Oct 12, 2018 (152)
85 ILLUMINA ss3633515924 Oct 12, 2018 (152)
86 ILLUMINA ss3634243298 Oct 12, 2018 (152)
87 ILLUMINA ss3635190532 Oct 12, 2018 (152)
88 ILLUMINA ss3635921724 Oct 12, 2018 (152)
89 ILLUMINA ss3636932434 Oct 12, 2018 (152)
90 ILLUMINA ss3637674961 Oct 12, 2018 (152)
91 ILLUMINA ss3638786181 Oct 12, 2018 (152)
92 ILLUMINA ss3639396011 Oct 12, 2018 (152)
93 ILLUMINA ss3639729061 Oct 12, 2018 (152)
94 ILLUMINA ss3640897823 Oct 12, 2018 (152)
95 ILLUMINA ss3643715275 Oct 12, 2018 (152)
96 URBANLAB ss3649016378 Oct 12, 2018 (152)
97 ILLUMINA ss3653429851 Oct 12, 2018 (152)
98 EGCUT_WGS ss3671720294 Jul 13, 2019 (153)
99 EVA_DECODE ss3723006067 Jul 13, 2019 (153)
100 ACPOP ss3736100545 Jul 13, 2019 (153)
101 ILLUMINA ss3745490398 Jul 13, 2019 (153)
102 EVA ss3768607334 Jul 13, 2019 (153)
103 ILLUMINA ss3772982714 Jul 13, 2019 (153)
104 KHV_HUMAN_GENOMES ss3811773554 Jul 13, 2019 (153)
105 EVA ss3831414391 Apr 26, 2020 (154)
106 EVA ss3839216568 Apr 26, 2020 (154)
107 EVA ss3844677056 Apr 26, 2020 (154)
108 HGDP ss3847929951 Apr 26, 2020 (154)
109 SGDP_PRJ ss3870994094 Apr 26, 2020 (154)
110 KRGDB ss3918595259 Apr 26, 2020 (154)
111 KOGIC ss3964841702 Apr 26, 2020 (154)
112 EVA ss3984612095 Apr 26, 2021 (155)
113 EVA ss3985389036 Apr 26, 2021 (155)
114 EVA ss4017414054 Apr 26, 2021 (155)
115 TOPMED ss4804205457 Apr 26, 2021 (155)
116 TOMMO_GENOMICS ss5190996759 Apr 26, 2021 (155)
117 1000G_HIGH_COVERAGE ss5278940348 Oct 16, 2022 (156)
118 EVA ss5315363800 Oct 16, 2022 (156)
119 EVA ss5384454561 Oct 16, 2022 (156)
120 HUGCELL_USP ss5475322272 Oct 16, 2022 (156)
121 EVA ss5509551387 Oct 16, 2022 (156)
122 1000G_HIGH_COVERAGE ss5570270714 Oct 16, 2022 (156)
123 SANFORD_IMAGENETICS ss5646413237 Oct 16, 2022 (156)
124 TOMMO_GENOMICS ss5733720538 Oct 16, 2022 (156)
125 EVA ss5799769029 Oct 16, 2022 (156)
126 YY_MCH ss5810133462 Oct 16, 2022 (156)
127 EVA ss5831223369 Oct 16, 2022 (156)
128 EVA ss5856572063 Oct 16, 2022 (156)
129 EVA ss5891027087 Oct 16, 2022 (156)
130 EVA ss5975664797 Oct 16, 2022 (156)
131 1000Genomes NC_000008.10 - 128408116 Oct 12, 2018 (152)
132 1000Genomes_30x NC_000008.11 - 127395871 Oct 16, 2022 (156)
133 The Avon Longitudinal Study of Parents and Children NC_000008.10 - 128408116 Oct 12, 2018 (152)
134 Genome-wide autozygosity in Daghestan NC_000008.9 - 128477298 Apr 26, 2020 (154)
135 Genetic variation in the Estonian population NC_000008.10 - 128408116 Oct 12, 2018 (152)
136 The Danish reference pan genome NC_000008.10 - 128408116 Apr 26, 2020 (154)
137 gnomAD - Genomes NC_000008.11 - 127395871 Apr 26, 2021 (155)
138 Genome of the Netherlands Release 5 NC_000008.10 - 128408116 Apr 26, 2020 (154)
139 HGDP-CEPH-db Supplement 1 NC_000008.9 - 128477298 Apr 26, 2020 (154)
140 HapMap NC_000008.11 - 127395871 Apr 26, 2020 (154)
141 KOREAN population from KRGDB NC_000008.10 - 128408116 Apr 26, 2020 (154)
142 Korean Genome Project NC_000008.11 - 127395871 Apr 26, 2020 (154)
143 Northern Sweden NC_000008.10 - 128408116 Jul 13, 2019 (153)
144 Ancient Sardinia genome-wide 1240k capture data generation and analysis NC_000008.10 - 128408116 Apr 26, 2021 (155)
145 CNV burdens in cranial meningiomas NC_000008.10 - 128408116 Apr 26, 2021 (155)
146 Qatari NC_000008.10 - 128408116 Apr 26, 2020 (154)
147 SGDP_PRJ NC_000008.10 - 128408116 Apr 26, 2020 (154)
148 Siberian NC_000008.10 - 128408116 Apr 26, 2020 (154)
149 8.3KJPN NC_000008.10 - 128408116 Apr 26, 2021 (155)
150 14KJPN NC_000008.11 - 127395871 Oct 16, 2022 (156)
151 TopMed NC_000008.11 - 127395871 Apr 26, 2021 (155)
152 UK 10K study - Twins NC_000008.10 - 128408116 Oct 12, 2018 (152)
153 A Vietnamese Genetic Variation Database NC_000008.10 - 128408116 Jul 13, 2019 (153)
154 ALFA NC_000008.11 - 127395871 Apr 26, 2021 (155)
Help

History tab displays RefSNPs (Associated ID) from previous builds (Build) that now support the current RefSNP, and the dates, when the history was updated for each Associated ID (History Updated).

Associated ID History Updated (Build)
rs17382216 Oct 08, 2004 (123)
rs56641538 May 27, 2008 (130)
rs57019326 May 23, 2008 (130)
Added to this RefSNP Cluster:
Submission IDs Observation SPDI Canonical SPDI Source RSIDs
513215, 607843, ss84035942, ss85514096, ss108389966, ss113758869, ss116186732, ss162786877, ss165717401, ss167127078, ss199771211, ss280003843, ss294183425, ss479300540, ss825341795, ss1397539577, ss1595672723, ss1713070953, ss2635188360, ss3639396011, ss3639729061, ss3643715275, ss3847929951 NC_000008.9:128477297:C:T NC_000008.11:127395870:C:T (self)
44109173, 24542733, 17458542, 9050359, 10952162, 25772653, 9385410, 614963, 161534, 11371270, 23011074, 6113161, 48966066, 24542733, 5451795, ss223978720, ss234627304, ss241441345, ss479303694, ss479685376, ss484450689, ss536617383, ss561069609, ss655503991, ss778734962, ss782671879, ss783640585, ss831922555, ss832644565, ss833235254, ss834194492, ss986056377, ss1075916669, ss1331909761, ss1431670535, ss1582885422, ss1621728517, ss1664722550, ss1752712076, ss1805761049, ss1929329340, ss2025368142, ss2095215273, ss2153596807, ss2627158916, ss2634803770, ss2634803771, ss2709383762, ss2711149505, ss2872694478, ss3003997383, ss3348404625, ss3630158658, ss3632699941, ss3633515924, ss3634243298, ss3635190532, ss3635921724, ss3636932434, ss3637674961, ss3638786181, ss3640897823, ss3653429851, ss3671720294, ss3736100545, ss3745490398, ss3768607334, ss3772982714, ss3831414391, ss3839216568, ss3870994094, ss3918595259, ss3984612095, ss3985389036, ss4017414054, ss5190996759, ss5315363800, ss5384454561, ss5509551387, ss5646413237, ss5799769029, ss5831223369, ss5975664797 NC_000008.10:128408115:C:T NC_000008.11:127395870:C:T (self)
57796649, 311146368, 3724764, 21219703, 67557642, 641583017, 1769060952, ss2307374107, ss3026469695, ss3649016378, ss3723006067, ss3811773554, ss3844677056, ss3964841702, ss4804205457, ss5278940348, ss5475322272, ss5570270714, ss5733720538, ss5810133462, ss5856572063, ss5891027087 NC_000008.11:127395870:C:T NC_000008.11:127395870:C:T (self)
ss22656422 NT_008046.14:41626294:C:T NC_000008.11:127395870:C:T (self)
ss14900174, ss24546178, ss44847578, ss66032148, ss66730519, ss66891013, ss66994680, ss69062064, ss70372184, ss70486966, ss71011212, ss75691759, ss76422534, ss84964632, ss97902679, ss105437235, ss120035141, ss121343926, ss134527242, ss152768183, ss156881649, ss159131881, ss159904878, ss169492218, ss170267259 NT_008046.16:41681664:C:T NC_000008.11:127395870:C:T (self)
Help

Publications tab displays PubMed articles citing the variation as a listing of PMID, Title, Author, Year, Journal, ordered by Year, descending.

8 citations for rs10505476
PMID Title Author Year Journal
18373104 Genetic variants in the 8q24 locus and risk of testicular germ cell tumors. Cook MB et al. 2008 Human genetics
18535017 Pooled analysis of genetic variation at chromosome 8q24 and colorectal neoplasia risk. Berndt SI et al. 2008 Human molecular genetics
19528667 Association of chromosome 8q variants with prostate cancer risk in Caucasian and Hispanic men. Beuten J et al. 2009 Carcinogenesis
20659471 Genetic heterogeneity in colorectal cancer associations between African and European americans. Kupfer SS et al. 2010 Gastroenterology
20978189 Pesticide use modifies the association between genetic variants on chromosome 8q24 and prostate cancer. Koutros S et al. 2010 Cancer research
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21456070 GWAS SNP Replication among African American and European American men in the North Carolina-Louisiana prostate cancer project (PCaP). Xu Z et al. 2011 The Prostate
26159557 Association of three 8q24 polymorphisms with prostate cancer susceptibility: evidence from a meta-analysis with 50,854 subjects. Li Q et al. 2015 Scientific reports
Help

The Flanks tab provides retrieving flanking sequences of a SNP on all molecules that have placements.

Genome context:
Select flank length:

Genomic regions, transcripts, and products
Top Help

NCBI Graphical Sequence Viewer display of the genomic region, transcripts and protein products for the reported RefSNP (rs).
Use the zoom option to view the nucleotides around the RefSNP and find other neighboring RefSNPs.
Visit Sequence Viewer for help with navigating inside the display and modifying the selection of displayed data tracks.

Software version is: 2.0.1.post761+d5e8e07