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dbSNP Short Genetic Variations

Welcome to the Reference SNP (rs) Report

All alleles are reported in the Forward orientation. Click on the Variant Details tab for details on Genomic Placement, Gene, and Amino Acid changes. HGVS names are in the HGVS tab.

Reference SNP (rs) Report

This page reports data for a single dbSNP Reference SNP variation (RefSNP or rs) from the new redesigned dbSNP build.
Top of the page reports a concise summary for the rs, with more specific details included in the corresponding tabs below.
All alleles are reported in the Forward orientation. Use the Genomic View to inspect the nucleotides flanking the variant, and its neighbors.
For more information see Help documentation.

rs1280972

Current Build 156

Released September 21, 2022

Organism
Homo sapiens
Position
chr1:10918005 (GRCh38.p14) Help

The anchor position for this RefSNP. Includes all nucleotides potentially affected by this change, thus it can differ from HGVS, which is right-shifted. See here for details.

Alleles
A>G
Variation Type
SNV Single Nucleotide Variation
Frequency
G=0.340262 (90064/264690, TOPMED)
G=0.304107 (62365/205076, GENOGRAPHIC)
G=0.336200 (47072/140012, GnomAD) (+ 22 more)
G=0.30279 (22463/74186, ALFA)
G=0.41560 (11744/28258, 14KJPN)
G=0.42011 (7041/16760, 8.3KJPN)
G=0.3440 (2203/6404, 1000G_30x)
G=0.3444 (1725/5008, 1000G)
G=0.3029 (1357/4480, Estonian)
G=0.2841 (1095/3854, ALSPAC)
G=0.2931 (1087/3708, TWINSUK)
G=0.4195 (1229/2930, KOREAN)
G=0.3647 (760/2084, HGDP_Stanford)
G=0.3725 (704/1890, HapMap)
G=0.4329 (793/1832, Korea1K)
G=0.3377 (383/1134, Daghestan)
G=0.282 (281/998, GoNL)
G=0.283 (170/600, NorthernSweden)
A=0.376 (130/346, SGDP_PRJ)
G=0.352 (76/216, Qatari)
A=0.486 (101/208, Vietnamese)
G=0.12 (8/66, Ancient Sardinia)
G=0.33 (13/40, GENOME_DK)
A=0.50 (17/34, Siberian)
G=0.50 (17/34, Siberian)
Clinical Significance
Not Reported in ClinVar
Gene : Consequence
LOC105376735 : Intron Variant
Publications
0 citations
Genomic View
See rs on genome

ALFA Allele Frequency
The ALFA project provide aggregate allele frequency from dbGaP. More information is available on the project page including descriptions, data access, and terms of use.

Release Version: 20230706150541
Population Group Sample Size Ref Allele Alt Allele
Total Global 74186 A=0.69721 G=0.30279
European Sub 58854 A=0.70773 G=0.29227
African Sub 7160 A=0.6156 G=0.3844
African Others Sub 254 A=0.559 G=0.441
African American Sub 6906 A=0.6177 G=0.3823
Asian Sub 192 A=0.547 G=0.453
East Asian Sub 150 A=0.553 G=0.447
Other Asian Sub 42 A=0.52 G=0.48
Latin American 1 Sub 254 A=0.618 G=0.382
Latin American 2 Sub 1232 A=0.6218 G=0.3782
South Asian Sub 4958 A=0.7241 G=0.2759
Other Sub 1536 A=0.6797 G=0.3203


Help

Frequency tab displays a table of the reference and alternate allele frequencies reported by various studies and populations. Table lines, where Population="Global" refer to the entire study population, whereas lines, where Group="Sub", refer to a study-specific population subgroupings (i.e. AFR, CAU, etc.), if available. Frequency for the alternate allele (Alt Allele) is a ratio of samples observed-to-total, where the numerator (observed samples) is the number of chromosomes in the study with the minor allele present (found in "Sample size", where Group="Sub"), and the denominator (total samples) is the total number of all chromosomes in the study for the variant (found in "Sample size", where Group="Study-wide" and Population="Global").

Download
Study Population Group Sample Size Ref Allele Alt Allele
TopMed Global Study-wide 264690 A=0.659738 G=0.340262
Genographic Project Global Study-wide 205076 A=0.695893 G=0.304107
gnomAD - Genomes Global Study-wide 140012 A=0.663800 G=0.336200
gnomAD - Genomes European Sub 75832 A=0.70487 G=0.29513
gnomAD - Genomes African Sub 41928 A=0.61241 G=0.38759
gnomAD - Genomes American Sub 13652 A=0.62987 G=0.37013
gnomAD - Genomes Ashkenazi Jewish Sub 3324 A=0.6032 G=0.3968
gnomAD - Genomes East Asian Sub 3124 A=0.5647 G=0.4353
gnomAD - Genomes Other Sub 2152 A=0.6705 G=0.3295
Allele Frequency Aggregator Total Global 74186 A=0.69721 G=0.30279
Allele Frequency Aggregator European Sub 58854 A=0.70773 G=0.29227
Allele Frequency Aggregator African Sub 7160 A=0.6156 G=0.3844
Allele Frequency Aggregator South Asian Sub 4958 A=0.7241 G=0.2759
Allele Frequency Aggregator Other Sub 1536 A=0.6797 G=0.3203
Allele Frequency Aggregator Latin American 2 Sub 1232 A=0.6218 G=0.3782
Allele Frequency Aggregator Latin American 1 Sub 254 A=0.618 G=0.382
Allele Frequency Aggregator Asian Sub 192 A=0.547 G=0.453
14KJPN JAPANESE Study-wide 28258 A=0.58440 G=0.41560
8.3KJPN JAPANESE Study-wide 16760 A=0.57989 G=0.42011
1000Genomes_30x Global Study-wide 6404 A=0.6560 G=0.3440
1000Genomes_30x African Sub 1786 A=0.6036 G=0.3964
1000Genomes_30x Europe Sub 1266 A=0.7188 G=0.2812
1000Genomes_30x South Asian Sub 1202 A=0.7479 G=0.2521
1000Genomes_30x East Asian Sub 1170 A=0.5590 G=0.4410
1000Genomes_30x American Sub 980 A=0.673 G=0.327
1000Genomes Global Study-wide 5008 A=0.6556 G=0.3444
1000Genomes African Sub 1322 A=0.6120 G=0.3880
1000Genomes East Asian Sub 1008 A=0.5585 G=0.4415
1000Genomes Europe Sub 1006 A=0.7087 G=0.2913
1000Genomes South Asian Sub 978 A=0.747 G=0.253
1000Genomes American Sub 694 A=0.673 G=0.327
Genetic variation in the Estonian population Estonian Study-wide 4480 A=0.6971 G=0.3029
The Avon Longitudinal Study of Parents and Children PARENT AND CHILD COHORT Study-wide 3854 A=0.7159 G=0.2841
UK 10K study - Twins TWIN COHORT Study-wide 3708 A=0.7069 G=0.2931
KOREAN population from KRGDB KOREAN Study-wide 2930 A=0.5805 G=0.4195
HGDP-CEPH-db Supplement 1 Global Study-wide 2084 A=0.6353 G=0.3647
HGDP-CEPH-db Supplement 1 Est_Asia Sub 470 A=0.623 G=0.377
HGDP-CEPH-db Supplement 1 Central_South_Asia Sub 414 A=0.696 G=0.304
HGDP-CEPH-db Supplement 1 Middle_Est Sub 350 A=0.654 G=0.346
HGDP-CEPH-db Supplement 1 Europe Sub 320 A=0.713 G=0.287
HGDP-CEPH-db Supplement 1 Africa Sub 242 A=0.587 G=0.413
HGDP-CEPH-db Supplement 1 America Sub 216 A=0.523 G=0.477
HGDP-CEPH-db Supplement 1 Oceania Sub 72 A=0.43 G=0.57
HapMap Global Study-wide 1890 A=0.6275 G=0.3725
HapMap American Sub 770 A=0.652 G=0.348
HapMap African Sub 692 A=0.611 G=0.389
HapMap Asian Sub 252 A=0.556 G=0.444
HapMap Europe Sub 176 A=0.688 G=0.312
Korean Genome Project KOREAN Study-wide 1832 A=0.5671 G=0.4329
Genome-wide autozygosity in Daghestan Global Study-wide 1134 A=0.6623 G=0.3377
Genome-wide autozygosity in Daghestan Daghestan Sub 628 A=0.653 G=0.347
Genome-wide autozygosity in Daghestan Near_East Sub 144 A=0.611 G=0.389
Genome-wide autozygosity in Daghestan Central Asia Sub 120 A=0.658 G=0.342
Genome-wide autozygosity in Daghestan Europe Sub 108 A=0.722 G=0.278
Genome-wide autozygosity in Daghestan South Asian Sub 98 A=0.76 G=0.24
Genome-wide autozygosity in Daghestan Caucasus Sub 36 A=0.61 G=0.39
Genome of the Netherlands Release 5 Genome of the Netherlands Study-wide 998 A=0.718 G=0.282
Northern Sweden ACPOP Study-wide 600 A=0.717 G=0.283
SGDP_PRJ Global Study-wide 346 A=0.376 G=0.624
Qatari Global Study-wide 216 A=0.648 G=0.352
A Vietnamese Genetic Variation Database Global Study-wide 208 A=0.486 G=0.514
Ancient Sardinia genome-wide 1240k capture data generation and analysis Global Study-wide 66 A=0.88 G=0.12
The Danish reference pan genome Danish Study-wide 40 A=0.68 G=0.33
Siberian Global Study-wide 34 A=0.50 G=0.50
Help

Variant Details tab shows known variant placements on genomic sequences: chromosomes (NC_), RefSeqGene, pseudogenes or genomic regions (NG_), and in a separate table: on transcripts (NM_) and protein sequences (NP_). The corresponding transcript and protein locations are listed in adjacent lines, along with molecular consequences from Sequence Ontology. When no protein placement is available, only the transcript is listed. Column "Codon[Amino acid]" shows the actual base change in the format of "Reference > Alternate" allele, including the nucleotide codon change in transcripts, and the amino acid change in proteins, respectively, allowing for known ribosomal slippage sites. To view nucleotides adjacent to the variant use the Genomic View at the bottom of the page - zoom into the sequence until the nucleotides around the variant become visible.

Genomic Placements
Sequence name Change
GRCh38.p14 chr 1 NC_000001.11:g.10918005A>G
GRCh37.p13 chr 1 NC_000001.10:g.10978062A>G
Gene: LOC105376735, uncharacterized LOC105376735 (minus strand)
Molecule type Change Amino acid[Codon] SO Term
LOC105376735 transcript XR_001737778.2:n. N/A Intron Variant
Help

Clinical Significance tab shows a list of clinical significance entries from ClinVar associated with the variation, per allele. Click on the RCV accession (i.e. RCV000001615.2) or Allele ID (i.e. 12274) to access full ClinVar report.

Not Reported in ClinVar
Help

Aliases tab displays HGVS names representing the variant placements and allele changes on genomic, transcript and protein sequences, per allele. HGVS name is an expression for reporting sequence accession and version, sequence type, position, and allele change. The column "Note" can have two values: "diff" means that there is a difference between the reference allele (variation interval) at the placement reported in HGVS name and the reference alleles reported in other HGVS names, and "rev" means that the sequence of this variation interval at the placement reported in HGVS name is in reverse orientation to the sequence(s) of this variation in other HGVS names not labeled as "rev".

Placement A= G
GRCh38.p14 chr 1 NC_000001.11:g.10918005= NC_000001.11:g.10918005A>G
GRCh37.p13 chr 1 NC_000001.10:g.10978062= NC_000001.10:g.10978062A>G
Help

Submissions tab displays variations originally submitted to dbSNP, now supporting this RefSNP cluster (rs). We display Submitter handle, Submission identifier, Date and Build number, when the submission appeared for the first time. Direct submissions to dbSNP have Submission ID in the form of an ss-prefixed number (ss#). Other supporting variations are listed in the table without ss#.

99 SubSNP, 24 Frequency submissions
No Submitter Submission ID Date (Build)
1 KWOK ss2007873 Oct 18, 2000 (87)
2 SC_JCM ss2628089 Nov 08, 2000 (89)
3 TSC-CSHL ss3348505 Sep 28, 2001 (100)
4 WI_SSAHASNP ss11430618 Jul 11, 2003 (116)
5 CSHL-HAPMAP ss17362117 Feb 27, 2004 (120)
6 PERLEGEN ss23159924 Sep 20, 2004 (123)
7 ABI ss44017160 Mar 15, 2006 (126)
8 KRIBB_YJKIM ss65837031 Dec 01, 2006 (127)
9 AFFY ss65978940 Dec 01, 2006 (127)
10 ILLUMINA ss66637640 Dec 01, 2006 (127)
11 ILLUMINA ss67040701 Dec 01, 2006 (127)
12 ILLUMINA ss67365291 Dec 01, 2006 (127)
13 PERLEGEN ss68758459 May 18, 2007 (127)
14 ILLUMINA ss70416366 May 18, 2007 (127)
15 ILLUMINA ss70585536 May 25, 2008 (130)
16 ILLUMINA ss71128389 May 18, 2007 (127)
17 ILLUMINA ss75497754 Dec 06, 2007 (129)
18 HGSV ss80742291 Dec 15, 2007 (130)
19 KRIBB_YJKIM ss83711753 Dec 15, 2007 (130)
20 HUMANGENOME_JCVI ss99185855 Feb 06, 2009 (130)
21 BGI ss102719297 Dec 01, 2009 (131)
22 1000GENOMES ss107989595 Jan 22, 2009 (130)
23 ILLUMINA-UK ss118495605 Feb 14, 2009 (130)
24 ILLUMINA ss121603945 Dec 01, 2009 (131)
25 ENSEMBL ss139281780 Dec 01, 2009 (131)
26 ILLUMINA ss153283732 Dec 01, 2009 (131)
27 GMI ss154632196 Dec 01, 2009 (131)
28 ILLUMINA ss159235513 Dec 01, 2009 (131)
29 COMPLETE_GENOMICS ss166091311 Jul 04, 2010 (132)
30 ILLUMINA ss170233889 Jul 04, 2010 (132)
31 ILLUMINA ss172249352 Jul 04, 2010 (132)
32 BUSHMAN ss198013549 Jul 04, 2010 (132)
33 1000GENOMES ss218234856 Jul 14, 2010 (132)
34 1000GENOMES ss230425437 Jul 14, 2010 (132)
35 1000GENOMES ss238140690 Jul 15, 2010 (132)
36 GMI ss275712655 May 04, 2012 (137)
37 PJP ss290622713 May 09, 2011 (134)
38 ILLUMINA ss533119201 Sep 08, 2015 (146)
39 TISHKOFF ss553792979 Apr 25, 2013 (138)
40 SSMP ss647572837 Apr 25, 2013 (138)
41 ILLUMINA ss825385640 Apr 01, 2015 (144)
42 ILLUMINA ss832747846 Jul 12, 2019 (153)
43 EVA-GONL ss974853698 Aug 21, 2014 (142)
44 JMKIDD_LAB ss1067667539 Aug 21, 2014 (142)
45 1000GENOMES ss1289673950 Aug 21, 2014 (142)
46 HAMMER_LAB ss1397239643 Sep 08, 2015 (146)
47 DDI ss1425711256 Apr 01, 2015 (144)
48 EVA_GENOME_DK ss1573886153 Apr 01, 2015 (144)
49 EVA_UK10K_ALSPAC ss1599543675 Apr 01, 2015 (144)
50 EVA_UK10K_TWINSUK ss1642537708 Apr 01, 2015 (144)
51 EVA_SVP ss1712310987 Apr 01, 2015 (144)
52 HAMMER_LAB ss1793899182 Sep 08, 2015 (146)
53 WEILL_CORNELL_DGM ss1918052741 Feb 12, 2016 (147)
54 GENOMED ss1966683960 Jul 19, 2016 (147)
55 JJLAB ss2019540493 Sep 14, 2016 (149)
56 USC_VALOUEV ss2147537805 Dec 20, 2016 (150)
57 HUMAN_LONGEVITY ss2160031300 Dec 20, 2016 (150)
58 SYSTEMSBIOZJU ss2624286624 Nov 08, 2017 (151)
59 GRF ss2697433966 Nov 08, 2017 (151)
60 GNOMAD ss2751598991 Nov 08, 2017 (151)
61 SWEGEN ss2986293001 Nov 08, 2017 (151)
62 BIOINF_KMB_FNS_UNIBA ss3023534560 Nov 08, 2017 (151)
63 CSHL ss3343316352 Nov 08, 2017 (151)
64 ILLUMINA ss3626025460 Oct 11, 2018 (152)
65 ILLUMINA ss3637737154 Oct 11, 2018 (152)
66 ILLUMINA ss3638889882 Oct 11, 2018 (152)
67 ILLUMINA ss3639441802 Oct 11, 2018 (152)
68 ILLUMINA ss3642751041 Oct 11, 2018 (152)
69 URBANLAB ss3646599381 Oct 11, 2018 (152)
70 EGCUT_WGS ss3654393469 Jul 12, 2019 (153)
71 EVA_DECODE ss3686159637 Jul 12, 2019 (153)
72 ACPOP ss3726788508 Jul 12, 2019 (153)
73 EVA ss3745826463 Jul 12, 2019 (153)
74 PACBIO ss3783323705 Jul 12, 2019 (153)
75 PACBIO ss3788998308 Jul 12, 2019 (153)
76 PACBIO ss3793871046 Jul 12, 2019 (153)
77 KHV_HUMAN_GENOMES ss3798846838 Jul 12, 2019 (153)
78 EVA ss3826022400 Apr 25, 2020 (154)
79 HGDP ss3847324438 Apr 25, 2020 (154)
80 SGDP_PRJ ss3848189145 Apr 25, 2020 (154)
81 KRGDB ss3893071147 Apr 25, 2020 (154)
82 KOGIC ss3943818647 Apr 25, 2020 (154)
83 EVA ss3984778394 Apr 25, 2021 (155)
84 EVA ss4016893170 Apr 25, 2021 (155)
85 TOPMED ss4439155599 Apr 25, 2021 (155)
86 TOMMO_GENOMICS ss5142465462 Apr 25, 2021 (155)
87 1000G_HIGH_COVERAGE ss5241168471 Oct 12, 2022 (156)
88 GENOGRAPHIC ss5314461638 Oct 12, 2022 (156)
89 EVA ss5316737060 Oct 12, 2022 (156)
90 HUGCELL_USP ss5442373170 Oct 12, 2022 (156)
91 EVA ss5505765741 Oct 12, 2022 (156)
92 1000G_HIGH_COVERAGE ss5512923862 Oct 12, 2022 (156)
93 SANFORD_IMAGENETICS ss5624920857 Oct 12, 2022 (156)
94 TOMMO_GENOMICS ss5666764552 Oct 12, 2022 (156)
95 YY_MCH ss5800320739 Oct 12, 2022 (156)
96 EVA ss5831537125 Oct 12, 2022 (156)
97 EVA ss5848782453 Oct 12, 2022 (156)
98 EVA ss5907035541 Oct 12, 2022 (156)
99 EVA ss5936747894 Oct 12, 2022 (156)
100 1000Genomes NC_000001.10 - 10978062 Oct 11, 2018 (152)
101 1000Genomes_30x NC_000001.11 - 10918005 Oct 12, 2022 (156)
102 The Avon Longitudinal Study of Parents and Children NC_000001.10 - 10978062 Oct 11, 2018 (152)
103 Genome-wide autozygosity in Daghestan NC_000001.9 - 10900649 Apr 25, 2020 (154)
104 Genetic variation in the Estonian population NC_000001.10 - 10978062 Oct 11, 2018 (152)
105 Genographic Project NC_000001.11 - 10918005 Oct 12, 2022 (156)
106 The Danish reference pan genome NC_000001.10 - 10978062 Apr 25, 2020 (154)
107 gnomAD - Genomes NC_000001.11 - 10918005 Apr 25, 2021 (155)
108 Genome of the Netherlands Release 5 NC_000001.10 - 10978062 Apr 25, 2020 (154)
109 HGDP-CEPH-db Supplement 1 NC_000001.9 - 10900649 Apr 25, 2020 (154)
110 HapMap NC_000001.11 - 10918005 Apr 25, 2020 (154)
111 KOREAN population from KRGDB NC_000001.10 - 10978062 Apr 25, 2020 (154)
112 Korean Genome Project NC_000001.11 - 10918005 Apr 25, 2020 (154)
113 Northern Sweden NC_000001.10 - 10978062 Jul 12, 2019 (153)
114 Ancient Sardinia genome-wide 1240k capture data generation and analysis NC_000001.10 - 10978062 Apr 25, 2021 (155)
115 Qatari NC_000001.10 - 10978062 Apr 25, 2020 (154)
116 SGDP_PRJ NC_000001.10 - 10978062 Apr 25, 2020 (154)
117 Siberian NC_000001.10 - 10978062 Apr 25, 2020 (154)
118 8.3KJPN NC_000001.10 - 10978062 Apr 25, 2021 (155)
119 14KJPN NC_000001.11 - 10918005 Oct 12, 2022 (156)
120 TopMed NC_000001.11 - 10918005 Apr 25, 2021 (155)
121 UK 10K study - Twins NC_000001.10 - 10978062 Oct 11, 2018 (152)
122 A Vietnamese Genetic Variation Database NC_000001.10 - 10978062 Jul 12, 2019 (153)
123 ALFA NC_000001.11 - 10918005 Apr 25, 2021 (155)
Help

History tab displays RefSNPs (Associated ID) from previous builds (Build) that now support the current RefSNP, and the dates, when the history was updated for each Associated ID (History Updated).

Associated ID History Updated (Build)
rs17035972 Oct 07, 2004 (123)
rs60118760 May 25, 2008 (130)
Added to this RefSNP Cluster:
Submission IDs Observation SPDI Canonical SPDI Source RSIDs
ss80742291, ss3638889882, ss3639441802 NC_000001.8:10912327:A:G NC_000001.11:10918004:A:G (self)
1122, 2330, ss107989595, ss118495605, ss166091311, ss198013549, ss275712655, ss290622713, ss825385640, ss1397239643, ss1712310987, ss3642751041, ss3847324438 NC_000001.9:10900648:A:G NC_000001.11:10918004:A:G (self)
349699, 181657, 131717, 1388612, 77762, 248541, 73373, 4321, 94671, 206125, 54159, 434769, 181657, 37792, ss218234856, ss230425437, ss238140690, ss533119201, ss553792979, ss647572837, ss832747846, ss974853698, ss1067667539, ss1289673950, ss1425711256, ss1573886153, ss1599543675, ss1642537708, ss1793899182, ss1918052741, ss1966683960, ss2019540493, ss2147537805, ss2624286624, ss2697433966, ss2751598991, ss2986293001, ss3343316352, ss3626025460, ss3637737154, ss3654393469, ss3726788508, ss3745826463, ss3783323705, ss3788998308, ss3793871046, ss3826022400, ss3848189145, ss3893071147, ss3984778394, ss4016893170, ss5142465462, ss5316737060, ss5505765741, ss5624920857, ss5831537125, ss5936747894 NC_000001.10:10978061:A:G NC_000001.11:10918004:A:G (self)
449797, 66190, 2439438, 13045, 196648, 601656, 2761934, 10367338661, ss2160031300, ss3023534560, ss3646599381, ss3686159637, ss3798846838, ss3943818647, ss4439155599, ss5241168471, ss5314461638, ss5442373170, ss5512923862, ss5666764552, ss5800320739, ss5848782453, ss5907035541 NC_000001.11:10918004:A:G NC_000001.11:10918004:A:G (self)
ss11430618 NT_021937.15:1489995:A:G NC_000001.11:10918004:A:G (self)
ss17362117 NT_021937.16:5105120:A:G NC_000001.11:10918004:A:G (self)
ss2007873, ss2628089, ss3348505, ss23159924, ss44017160, ss65837031, ss65978940, ss66637640, ss67040701, ss67365291, ss68758459, ss70416366, ss70585536, ss71128389, ss75497754, ss83711753, ss99185855, ss102719297, ss121603945, ss139281780, ss153283732, ss154632196, ss159235513, ss170233889, ss172249352 NT_021937.19:6982793:A:G NC_000001.11:10918004:A:G (self)
Help

Publications tab displays PubMed articles citing the variation as a listing of PMID, Title, Author, Year, Journal, ordered by Year, descending.

No publications for rs1280972

Help

The Flanks tab provides retrieving flanking sequences of a SNP on all molecules that have placements.

Genome context:
Select flank length:

Genomic regions, transcripts, and products
Top Help

NCBI Graphical Sequence Viewer display of the genomic region, transcripts and protein products for the reported RefSNP (rs).
Use the zoom option to view the nucleotides around the RefSNP and find other neighboring RefSNPs.
Visit Sequence Viewer for help with navigating inside the display and modifying the selection of displayed data tracks.

Software version is: 2.0.1.post761+d5e8e07