dbGaP Collections

A dbGaP Collection provides streamlined access to data across dbGaP studies or portions of dbGaP studies that share the same consent group, disease, or funding project. Data access for a collection is controlled by a single data access committee. The data in a collection is not harmonized across studies or otherwise altered from the original study.

Investigators using data within a dbGaP collection are required to follow the use restrictions and acknowledgement instructions from the original dataset.

The following is a list of currently available dbGaP Collections.

  • dbGaP Collection: Compilation of Individual-Level Genomic Data for General Research Use

    This study contains all authorized individual-level genomic datasets currently in dbGaP that are approved for General Research Use (GRU) and have no further limitations beyond those outlined in the model Data Use Certification Agreement. Access to this study will include any additional authorized individual-level GRU datasets that become available. Renewal of this study is required annually.

  • dbGaP Collection: NIH Autism -omics Studies

    This dbGaP umbrella study consists of substudies that include GWAS, sequencing (targeted, exome, whole genome), transcriptomics, etc, across many different cohorts. Many of the datasets have been curated and harmonized with NDAR prior to submission to dbGaP.

  • dbGaP Collection: Open Translational Science in Schizophrenia (OPTICS)

    This dbGaP collection consists of all genetic studies of schizophrenia available in dbGaP that have been consented for general research use. The goal is to facilitate identification of datasets with related scientific content in order to expedite the application process and ascertainment of datasets of interest for increased scientific discovery.

  • dbGaP Collection: Psychiatric Genomics Consortium (PGC) dbGaP Datasets

    The collection includes cases and controls used in the GWAS meta-analysis of neuropsychiatric phenotypes studied by investigators in the Psychiatric Genomics Consortium including major depression, bipolar disorder, attention deficit and hyperactivity disorder, schizophrenia, Tourette Syndrome, and obsessive-compulsive disorder. The consent type for data sets includes general research use as well as phenotype-specific restricted usage. This dbGaP collection was created to facilitate identification of datasets used in PGC analyses in order to expedite the application and ascertainment process for PGC members wishing to access data within the consortium. Non-PGC members may also apply for this dbGaP collection.

  • dbGaP Collection: NHLBI Heart Failure Related dbGaP Data (No IRB requirement)

    The NHLBI Big Data Analysis Challenge: Heart Failure Data Collection contains all NHLBI studies currently in dbGaP that contain data that may be relevant to research on heart failure. The studies in this collection are approved for General Research Use (GRU), Health/Medical/Biomedical Use (HMB), or Disease-Specific Use (DS) that permits research on heart failure. These studies span a variety of study designs, inclusion and exclusion criteria, sample sizes, and provide a wide breadth and depth of phenotype data on study participants. The available genomic data in these studies also varies, including genotyping arrays, sequencing (targeted, exome, whole genome), and additional -omic data (e.g., RNA or metabolite profiles).