Membrane-associated ring finger (C3HC4) 8 [Mus musculus]

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MARCH8 attenuates cGAS-mediated innate immune responses through ubiquitylation. [Sci Signal. 2022]
MARCH8 attenuates cGAS-mediated innate immune responses through ubiquitylation.
Yang X, Shi C, Li H, Shen S, Su C, Yin H. Sci Signal. 2022 May 3; 15(732):eabk3067. Epub 2022 May 3.
E3 Ubiquitin Ligase MARCH8 Promotes Pancreatic Cancer Growth and Metastasis by Activating STAT3 via Degradation of PTPN4. [Pancreas. 2023]
E3 Ubiquitin Ligase MARCH8 Promotes Pancreatic Cancer Growth and Metastasis by Activating STAT3 via Degradation of PTPN4.
Chen C, Wang Y, Zhao Q, Li GD, Wang YH, Xu LC, Huang HZ, Song G, Li WT, He XH. Pancreas. 2023 Apr 1; 52(4):e224-e234. Epub 2023 Sep 25.
Ubiquitin-like protein 3 (UBL3) is required for MARCH ubiquitination of major histocompatibility complex class II and CD86. [Nat Commun. 2022]
Ubiquitin-like protein 3 (UBL3) is required for MARCH ubiquitination of major histocompatibility complex class II and CD86.
Liu H, Wilson KR, Firth AM, Macri C, Schriek P, Blum AB, Villar J, Wormald S, Shambrook M, Xu B, et al. Nat Commun. 2022 Apr 11; 13(1):1934. Epub 2022 Apr 11.

RefSeq protein isoforms
See 14 reference sequence protein isoforms for the Marchf8 gene.

Nucleotide
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Transcript/Protein Information [PANTHER Classification System]
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PANTHER Classification System
reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome

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Protein