cullin 4B, isoform CRA_b [Homo sapiens]

Run BLAST
Find regions of similarity between this sequence and other sequences using BLAST.
Identify Conserved Domains
View conserved domains detected in this protein sequence using CD-search.
Show in Genome Data Viewer
Opens the Genome Data Viewer, NCBI's genome browser, at the genomic location at which this sequence is annotated. View this sequence in the context of other features annotated at the same location and browse to other genome regions.

CUL4B mutations impair human cortical neurogenesis through PP2A-dependent inhibition of AKT and ERK. [Cell Death Dis. 2024]
CUL4B mutations impair human cortical neurogenesis through PP2A-dependent inhibition of AKT and ERK.
Ma Y, Liu X, Zhou M, Sun W, Jiang B, Liu Q, Wang M, Zou Y, Liu Q, Gong Y, et al. Cell Death Dis. 2024 Feb 8; 15(2):121. Epub 2024 Feb 8.
The CUL4B-based E3 ubiquitin ligase regulates mitosis and brain development by recruiting phospho-specific DCAFs. [EMBO J. 2023]
The CUL4B-based E3 ubiquitin ligase regulates mitosis and brain development by recruiting phospho-specific DCAFs.
Stier A, Gilberto S, Mohamed WI, Royall LN, Helenius J, Mikicic I, Sajic T, Beli P, Müller DJ, Jessberger S, et al. EMBO J. 2023 Sep 4; 42(17):e112847. Epub 2023 Jun 27.
CUL4B-associated epilepsy: Report of a novel truncating variant promoting drug-resistant seizures and systematic review of the literature. [Seizure. 2023]
CUL4B-associated epilepsy: Report of a novel truncating variant promoting drug-resistant seizures and systematic review of the literature.
Della Vecchia S, Lopergolo D, Trovato R, Pasquariello R, Ferrari AR, Bartolini E. Seizure. 2023 Jan; 104:32-37. Epub 2022 Nov 29.

RefSeq genomic sequence
See the genomic reference sequence for the CUL4B gene (NG_009388.1).
RefSeq protein isoforms
See 4 reference sequence protein isoforms for the CUL4B gene.

BioProject
Proteins related to BioProjects
Nucleotide
Nucleotide sequence from coding region
PubMed
PubMed articles cited by protein sequence record
Taxonomy
Taxonomy sequences associated with protein record
BioSystems
BioSystems
CDD Search Results
Display conserved domains within a protein
Conserved Domains (Concise)
Link to a concise list of conserved domains in a protein
Conserved Domains (Full)
Link to conserved domains within a protein
Domain Relatives
Display proteins with similar conserved domain architecture
Gene
Link to related Genes
Genome
Genome record encoding protein sequence
Identical Structures
3D structures for identical protein sequences
PubMed (Weighted)
Links to pubmed
Related Structures (List)
List of related structures
Related Structures (Summary)
Related structures

Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
PANTHER Classification System
reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome
reagent reviews [ExactAntigen/Labome]
reagent reviews
ExactAntigen/Labome

Your browsing activity is empty.

Activity recording is turned off.

Protein