DNA-PK hyperactivation occurs in deletion 11q chronic lymphocytic leukemia and is both a biomarker and therapeutic target for drug-resistant disease.
Kost SEF, Saleh A, Yuan SH, Kuzio B, Gibson SB, Yang L, Banerji V, Johnston JB, Katyal S. Blood Cancer J. 2023 Jan 27; 13(1):20. Epub 2023 Jan 27.