1-phosphatidylinositol 3-phosphate 5-kinase isoform X32 [Homo sapiens]

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Autophagy Inhibition by Targeting PIKfyve Potentiates Response to Immune Checkpoint Blockade in Prostate Cancer. [Nat Cancer. 2021]
Autophagy Inhibition by Targeting PIKfyve Potentiates Response to Immune Checkpoint Blockade in Prostate Cancer.
Qiao Y, Choi JE, Tien JC, Simko SA, Rajendiran T, Vo JN, Delekta AD, Wang L, Xiao L, Hodge NB, et al. Nat Cancer. 2021 Sep; 2:978-993. Epub 2021 Aug 2.
Inhibition of PIKfyve kinase prevents infection by Zaire ebolavirus and SARS-CoV-2. [Proc Natl Acad Sci U S A. 2020]
Inhibition of PIKfyve kinase prevents infection by Zaire ebolavirus and SARS-CoV-2.
Kang YL, Chou YY, Rothlauf PW, Liu Z, Soh TK, Cureton D, Case JB, Chen RE, Diamond MS, Whelan SPJ, et al. Proc Natl Acad Sci U S A. 2020 Aug 25; 117(34):20803-20813. Epub 2020 Aug 6.
PIKfyve inhibition increases exosome release and induces secretory autophagy. [Cell Mol Life Sci. 2016]
PIKfyve inhibition increases exosome release and induces secretory autophagy.
Hessvik NP, Øverbye A, Brech A, Torgersen ML, Jakobsen IS, Sandvig K, Llorente A. Cell Mol Life Sci. 2016 Dec; 73(24):4717-4737. Epub 2016 Jul 20.

RefSeq genomic sequence
See the genomic reference sequence for the PIKFYVE gene (NG_021188.2).
RefSeq mRNA
See reference mRNA sequence for the PIKFYVE gene (XM_017003574.2).
RefSeq protein isoforms
See 77 reference sequence protein isoforms for the PIKFYVE gene.

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Protein