RAF proto-oncogene serine/threonine-protein kinase isoform X2 [Homo sa - Protein

Run BLAST
Find regions of similarity between this sequence and other sequences using BLAST.
Identify Conserved Domains
View conserved domains detected in this protein sequence using CD-search.
Highlight Sequence Features
Opens the Highlight Feature Bar and highlights feature annotations from the FEATURES table of the record. The Highlight Feature Bar can be used to navigate to and highlight other features and provides links to display the highlighted region separately. Links in the FEATURES table will also highlight the corresponding region of the sequence. More...
Find in this Sequence
Finds sub-sequences or patterns in the sequence and highlights the matching regions. The tool works with standard single letter nucleotide or protein codes including ambiguities and can match Prosite patterns in protein sequences. More...
Show in Genome Data Viewer
Opens the Genome Data Viewer, NCBI's genome browser, at the genomic location at which this sequence is annotated. View this sequence in the context of other features annotated at the same location and browse to other genome regions.

RAF1 mutation leading to hypertrophic cardiomyopathy in a Chinese family with a history of sudden cardiac death: A diagnostic insight into Noonan syndrome. [Mol Genet Genomic Med. 2024]
RAF1 mutation leading to hypertrophic cardiomyopathy in a Chinese family with a history of sudden cardiac death: A diagnostic insight into Noonan syndrome.
Zheng J, Peng L, Cheng R, Li Z, Xie J, Huang E, Cheng J, Zhao Q. Mol Genet Genomic Med. 2024 Jan; 12(1):e2290. Epub 2023 Oct 3.
Molecular and cellular evidence for the impact of a hypertrophic cardiomyopathy-associated RAF1 variant on the structure and function of contractile machinery in bioartificial cardiac tissues. [Commun Biol. 2023]
Molecular and cellular evidence for the impact of a hypertrophic cardiomyopathy-associated RAF1 variant on the structure and function of contractile machinery in bioartificial cardiac tissues.
Nakhaei-Rad S, Haghighi F, Bazgir F, Dahlmann J, Busley AV, Buchholzer M, Kleemann K, Schänzer A, Borchardt A, Hahn A, et al. Commun Biol. 2023 Jun 21; 6(1):657. Epub 2023 Jun 21.
The GPCR-β-arrestin complex allosterically activates C-Raf by binding its amino terminus. [J Biol Chem. 2021]
The GPCR-β-arrestin complex allosterically activates C-Raf by binding its amino terminus.
Zang Y, Kahsai AW, Pakharukova N, Huang LY, Lefkowitz RJ. J Biol Chem. 2021 Dec; 297(6):101369. Epub 2021 Oct 30.

RefSeq genomic sequence
See the genomic reference sequence for the RAF1 gene (NG_007467.1).
RefSeq mRNA
See reference mRNA sequence for the RAF1 gene (XM_017006966.1).
RefSeq protein isoforms
See 18 reference sequence protein isoforms for the RAF1 gene.

BioProject
Proteins related to BioProjects
Nucleotide
Nucleotide sequence from coding region
Taxonomy
Taxonomy sequences associated with protein record
BioSystems
BioSystems
CDD Search Results
Display conserved domains within a protein
Conserved Domains (Concise)
Link to a concise list of conserved domains in a protein
Conserved Domains (Full)
Link to conserved domains within a protein
Domain Relatives
Display proteins with similar conserved domain architecture
Encoding mRNA
Link from protein to encoding mRNA
Gene
Link to related Genes
Genome
Genome record encoding protein sequence
Identical Structures
3D structures for identical protein sequences
PubMed (RefSeq)
Link to RefSeq PubMed articles
PubMed (Weighted)
Links to pubmed
SNP
Related SNPs

RAF proto-oncogene serine/threonine-protein kinase isoform X2 [Homo sapiens]
RAF proto-oncogene serine/threonine-protein kinase isoform X2 [Homo sapiens]
gi|1034634870|ref|XP_016862455.1|

Protein

Your browsing activity is empty.

Activity recording is turned off.

Protein