proto-oncogene tyrosine-protein kinase Src isoform X1 [Homo sapiens]

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An allosteric switch between the activation loop and a c-terminal palindromic phospho-motif controls c-Src function. [Nat Commun. 2023]
An allosteric switch between the activation loop and a c-terminal palindromic phospho-motif controls c-Src function.
Cuesta-Hernández HN, Contreras J, Soriano-Maldonado P, Sánchez-Wandelmer J, Yeung W, Martín-Hurtado A, Muñoz IG, Kannan N, Llimargas M, Muñoz J, et al. Nat Commun. 2023 Oct 17; 14(1):6548. Epub 2023 Oct 17.
The c-Src/LIST Positive Feedback Loop Sustains Tumor Progression and Chemoresistance. [Adv Sci (Weinh). 2023]
The c-Src/LIST Positive Feedback Loop Sustains Tumor Progression and Chemoresistance.
Wang X, Wang B, Li F, Li X, Guo T, Gao Y, Wang D, Huang W. Adv Sci (Weinh). 2023 Jul; 10(20):e2300115. Epub 2023 May 8.
Disordered Domain Shifts the Conformational Ensemble of the Folded Regulatory Domain of the Multidomain Oncoprotein c-Src. [Biomacromolecules. 2023]
Disordered Domain Shifts the Conformational Ensemble of the Folded Regulatory Domain of the Multidomain Oncoprotein c-Src.
Gurumoorthy V, Shrestha UR, Zhang Q, Pingali SV, Boder ET, Urban VS, Smith JC, Petridis L, O'Neill H. Biomacromolecules. 2023 Feb 13; 24(2):714-723. Epub 2023 Jan 24.

RefSeq genomic sequence
See the genomic reference sequence for the SRC gene (NG_023033.1).
RefSeq mRNA
See reference mRNA sequence for the SRC gene (XM_017028026.2).
RefSeq protein isoforms
See 59 reference sequence protein isoforms for the SRC gene.

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Protein