RecName: Full=Activin receptor type-1; AltName: Full=Activin receptor - Protein

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BMP-ACVR1 Axis is Critical for Efficacy of PRC2 Inhibitors in B-Cell Lymphoma. [Adv Sci (Weinh). 2024]
BMP-ACVR1 Axis is Critical for Efficacy of PRC2 Inhibitors in B-Cell Lymphoma.
Liu D, Li Z, Tan D, An Y, Chu L, Chen T, Li W, Zhou A, Xiang R, Zhang L, et al. Adv Sci (Weinh). 2024 Mar; 11(12):e2306499. Epub 2024 Jan 16.
A blocking monoclonal antibody reveals dimerization of intracellular domains of ALK2 associated with genetic disorders. [Nat Commun. 2023]
A blocking monoclonal antibody reveals dimerization of intracellular domains of ALK2 associated with genetic disorders.
Katagiri T, Tsukamoto S, Kuratani M, Tsuji S, Nakamura K, Ohte S, Kawaguchi Y, Takaishi K. Nat Commun. 2023 May 25; 14(1):2960. Epub 2023 May 25.
Recapitulation of pro-inflammatory signature of monocytes with ACVR1A mutation using FOP patient-derived iPSCs. [Orphanet J Rare Dis. 2022]
Recapitulation of pro-inflammatory signature of monocytes with ACVR1A mutation using FOP patient-derived iPSCs.
Maekawa H, Jin Y, Nishio M, Kawai S, Nagata S, Kamakura T, Yoshitomi H, Niwa A, Saito MK, Matsuda S, et al. Orphanet J Rare Dis. 2022 Sep 21; 17(1):364. Epub 2022 Sep 21.

RefSeq genomic sequence
See the genomic reference sequence for the ACVR1 gene (NG_008004.1).
RefSeq protein isoforms
See 7 reference sequence protein isoforms for the ACVR1 gene.

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Related structures

Q04771 [Domain Mapping of Disease Mut...]
Q04771
Domain Mapping of Disease Mutations
MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF) [MODBASE, Database of Comparat...]
MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF)
Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
PANTHER Classification System
reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome
reagent reviews [ExactAntigen/Labome]
reagent reviews
ExactAntigen/Labome
Evolutionary Trace of Functional Site [Evolutionary Trace of Functio...]
Evolutionary Trace of Functional Site

RecName: Full=Activin receptor type-1; AltName: Full=Activin receptor type I; Sh...
RecName: Full=Activin receptor type-1; AltName: Full=Activin receptor type I; Short=ACTR-I; AltName: Full=Activin receptor-like kinase 2; Short=ALK-2; AltName: Full=Serine/threonine-protein kinase receptor R1; Short=SKR1; AltName: Full=TGF-B superfamily receptor type I; Short=TSR-I; Flags: Precursor
gi|462447|sp|Q04771.1|ACVR1_HUMAN

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