RecName: Full=Nucleotide triphosphate diphosphatase NUDT15; AltName: F - Protein

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Association of NUDT15 gene polymorphism with adverse reaction, treatment efficacy, and dose of 6-mercaptopurine in patients with acute lymphoblastic leukemia: a systematic review and meta-analysis. [Haematologica. 2024]
Association of NUDT15 gene polymorphism with adverse reaction, treatment efficacy, and dose of 6-mercaptopurine in patients with acute lymphoblastic leukemia: a systematic review and meta-analysis.
Du S, Huang X, He X, Mao M, Chen M, Zhang R, Shao H, Lv Z, Liu X, Chuan J. Haematologica. 2024 Apr 1; 109(4):1053-1068. Epub 2024 Apr 1.
Analysis of the NUDT15 gene and metabolites of azathioprine in Japanese patients with inflammatory bowel disease. [BMC Gastroenterol. 2023]
Analysis of the NUDT15 gene and metabolites of azathioprine in Japanese patients with inflammatory bowel disease.
Suzuki S, Uchiyama K, Motoi Y, Yoshii Y, Inoue Y, Kubota T, Odahara S, Ohtaki Y, Takami S, Ito Z, et al. BMC Gastroenterol. 2023 Jul 15; 23(1):239. Epub 2023 Jul 15.
The c.415C>T polymorphism in NUDT15 is more frequent than the polymorphisms in TPMT in Chilean patients who use thiopurine drugs. [Pharmacogenet Genomics. 2023]
The c.415C>T polymorphism in NUDT15 is more frequent than the polymorphisms in TPMT in Chilean patients who use thiopurine drugs.
von Muhlenbrock C, Estay C, Covarrubias N, Miranda J, Venegas M. Pharmacogenet Genomics. 2023 Sep 1; 33(7):161-163. Epub 2023 Aug 2.

RefSeq genomic sequence
See the genomic reference sequence for the NUDT15 gene (NG_047021.1).
RefSeq protein isoforms
See 2 reference sequence protein isoforms for the NUDT15 gene.

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Q9NV35 [Domain Mapping of Disease Mut...]
Q9NV35
Domain Mapping of Disease Mutations
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RecName: Full=Nucleotide triphosphate diphosphatase NUDT15; AltName: Full=MutT h...
RecName: Full=Nucleotide triphosphate diphosphatase NUDT15; AltName: Full=MutT homolog 2; Short=MTH2; AltName: Full=Nucleoside diphosphate-linked moiety X motif 15; Short=Nudix motif 15; AltName: Full=Nucleoside diphosphate-linked to another moiety X hydrolase 15; Short=Nudix hydrolase 15
gi|68565944|sp|Q9NV35.1|NUD15_HUMAN

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