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Items: 17

  • The following term was not found in Protein Family Models: Tunyasuvunakool.
1.

type I-Fv CRISPR-associated protein Cas7fv

Cas7fv is one of the CRISPR associated (Cas) proteins of type I-F variant (I-Fv) CRISPR-Cas system. CRISPR (clustered regularly interspaced short palindromic repeats)-Cas modules are adaptive immune systems found in archaea and bacteria against foreign nucleic acids such as phages and plasmids via RNA-guided endonucleases. CRISPR-Cas systems are classified based on Cas protein content and arrangement in CRISPR-Cas loci into two main classes (1 and 2) and at least six types (I, II, III, IV, V, VI). Class 1 systems utilize multiple Cas proteins and CRISPR RNA (crRNA) to form an effector complex while class 2 systems employ a large, single effector with crRNA to mediate interference. Type I CRISPR-Cas systems are most widespread in nature and the Cas protein composition of the employed Cascade interference complexes differ between seven subtypes (A-F, U). Type I-F variant (I-Fv) is a subtype that rely on a minimal set of five Cas proteins and has structural differences with I-F and I-E Cascades. Double strand DNA recruitment and recognition in the type I-Fv Cascade is facilitated from the major groove side by Cas5fv instead of the large subunit Cas8 and the finger domain of Cas7fv.

Gene:
cas7fv
Date:
2021-10-22
Family Accession:
NF040577.1
Method:
HMM
2.

hydroxysqualene dehydroxylase HpnE

hydroxysqualene dehydroxylase HpnE reduces hydroxysqualene (HSQ) to squalene (SQ) and is a member of the amine oxidoreductase family

Date:
2021-09-27
Family Accession:
11496894
Method:
Sparcle
3.

pyocin knob domain-containing protein

pyocin knob domain-containing protein similar to R-type pyocins, which are high-molecular weight bacteriocins produced by some strains of Pseudomonas aeruginosa to specifically kill other strains of the same species; R-type pyocins are structurally similar to simple contractile tails, such as those of phage P2 and Mu; contains a lower baseplate protein N-terminal domain (BppL_N)

Date:
2021-02-09
Family Accession:
16062257
Method:
Sparcle
4.

YidC/Oxa1 family membrane protein insertase

YidC/Oxa1 family membrane protein insertase functions as a membrane protein chaperone and as an independent insertase for membrane proteins

Date:
2021-01-13
Family Accession:
15331943
Method:
Sparcle
5.

AP-3 complex subunit mu

AP-3 complex subunit mu is part of the AP-3 complex that is associated with the Golgi region as well as more peripheral structures

Date:
2021-08-10
Family Accession:
13000765
Method:
Sparcle
6.

FGFR/PDGFR/VEGFR family receptor tyrosine-protein kinase

FGFR/PDGFR/VEGFR family receptor tyrosine-protein kinase contains an extracellular ligand-binding region with immunoglobulin-like domains, a transmembrane segment, and an intracellular catalytic domain that catalyzes the transfer of the gamma-phosphoryl group from ATP to tyrosine (tyr) residues in protein substrates

Date:
2021-09-09
Family Accession:
10621977
Method:
Sparcle
7.

beta-ketoacyl synthase

beta-ketoacyl synthase similar to Pseudomonas aeruginosa beta-ketoacyl-[acyl-carrier-protein] synthase FabY that catalyzes the condensation of acetyl-CoA with malonyl-acyl carrier protein (ACP) to make the fatty acid synthesis primer beta-acetoacetyl-ACP

Date:
2021-02-12
Family Accession:
10093590
Method:
Sparcle
8.

GTP-binding protein

GTP-binding protein similar to Bacillus subtilis YsxC (also called GTP-binding protein EngB), an essential protein involved in cell division control

Date:
2021-04-20
Family Accession:
10799468
Method:
Sparcle
9.

FGFR/PDGFR/VEGFR family receptor tyrosine-protein kinase

FGFR/PDGFR/VEGFR family receptor tyrosine-protein kinase contains an extracellular ligand-binding region with immunoglobulin-like domains, a transmembrane segment, and an intracellular catalytic domain that catalyzes the transfer of the gamma-phosphoryl group from ATP to tyrosine (tyr) residues in protein substrates

Date:
2021-09-28
Family Accession:
12209028
Method:
Sparcle
10.

FGFR/PDGFR/VEGFR family receptor tyrosine-protein kinase

FGFR/PDGFR/VEGFR family receptor tyrosine-protein kinase contains an extracellular ligand-binding region with immunoglobulin-like domains, a transmembrane segment, and an intracellular catalytic domain that catalyzes the transfer of the gamma-phosphoryl group from ATP to tyrosine (tyr) residues in protein substrates

Date:
2021-08-17
Family Accession:
12207727
Method:
Sparcle
11.

type I-F CRISPR-associated endonuclease Cas1

type I-F CRISPR-associated endonuclease Cas1 which is the Cas1 protein particular to the YPEST subtype of CRISPR/Cas system; similar to Pectobacterium atrosepticum Cas1; Cas1 is virtually universal to CRISPR systems; CRISPR (clustered regularly interspaced short palindromic repeats) is a prokaryotic immunity system for foreign DNA, mostly from phage

Date:
2021-05-25
Family Accession:
10022725
Method:
Sparcle
12.

YidC/Oxa1 family membrane protein insertase

YidC/Oxa1 family membrane protein insertase functions as a membrane protein chaperone and as an independent insertase for membrane proteins

Date:
2021-01-13
Family Accession:
10489205
Method:
Sparcle
13.

eukaryotic translation initiation factor 3 subunit D

eukaryotic translation initiation factor 3 (eIF-3) subunit D is the mRNA cap-binding component of the eIF-3 complex, which is required for several steps in the initiation of protein synthesis of a specialized repertoire of mRNAs

Date:
2021-04-01
Family Accession:
10523878
Method:
Sparcle
14.

glycosyltransferase family 47 protein

glycosyltransferase family 47 protein, also called exostosin (EXT) family protein, similar to Arabidopsis thaliana xylogalacturonan beta-1,3-xylosyltransferase that catalyzes the transfer of xylose from UDP-xylose onto oligogalacturonides and endogenous acceptors

Date:
2021-01-28
Family Accession:
10503356
Method:
Sparcle
15.

exostosin

exostosin is a family 47 glycosyltransferase that is required for the biosynthesis of heparan-sulfate

Date:
2021-06-01
Family Accession:
10503393
Method:
Sparcle
16.

platelet-derived growth factor receptor beta

platelet-derived growth factor receptor beta is a receptor tyrosine kinase that catalyzes the transfer of the gamma-phosphoryl group from ATP to tyrosine (tyr) residues in protein substrates; binding to its ligands, the PDGFs, leads to receptor dimerization, trans phosphorylation and activation, and intracellular signaling

Date:
2021-08-26
Family Accession:
10441190
Method:
Sparcle
17.

type II CRISPR-associated endonuclease Cas1

type II CRISPR-associated endonuclease Cas1 which is the Cas1 variant of the NMENI subtype of CRISPR/Cas system; similar to Streptococcus thermophilus Cas1; Cas1 is virtually universal to CRISPR systems; CRISPR (clustered regularly interspaced short palindromic repeats) is a prokaryotic immunity system for foreign DNA, mostly from phage

Date:
2021-05-25
Family Accession:
10176709
Method:
Sparcle
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