Protein Family Models for Protein (Select 1655140894) - Protein Family Models

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Links from Protein

Items: 6

Select item 3898941.

Low molecular weight phosphotyrosine protein phosphatase

Date:: 2023-12-12

Family Accession:: NF013607.4
Method:: HMM

Select item 3473602.

new record, indexing in progress

Family Accession:

Select item 3164543.

new record, indexing in progress

Family Accession:

Select item 1467074.

new record, indexing in progress

Family Accession:

Select item 1461835.

new record, indexing in progress

Family Accession:

Select item 507526.

arsenate reductase (thioredoxin)

This family describes the well-studied thioredoxin-dependent arsenate reductase of Staphylococcus aureaus plasmid pI258 and other mechanistically similar arsenate reductases. The mechanism involves an intramolecular disulfide bond cascade, and aligned members of this family have four absolutely conserved Cys residues. This group of arsenate reductases belongs to the low-molecular weight protein-tyrosine phosphatase family (PF01451), as does a group of glutathione/glutaredoxin type arsenate reductases (TIGR02689). At least two other, non-homologous groups of arsenate reductases involved in arsenical resistance are also known. This enzyme reduces arsenate to arsenite, which may be more toxic but which is more easily exported.