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nitrilase-related carbon-nitrogen hydrolase
This family contains hydrolases that break carbon-nitrogen bonds [1]. The family includes: Nitrilase EC:3.5.5.1 Swiss:Q42965, Aliphatic amidase EC:3.5.1.4 Swiss:Q01360, Biotidinase EC:3.5.1.12 Swiss:P43251, Beta-ureidopropionase EC:3.5.1.6 Swiss:Q03248. Nitrilase-related proteins generally have a conserved E-K-C catalytic triad, and are multimeric alpha-beta-beta-alpha sandwich proteins [2]. [1]. 7987228. A new family of carbon-nitrogen hydrolases.. Bork P, Koonin EV;. Protein Sci 1994;3:1344-1346.. [2]. 11380987. The nitrilase superfamily: classification, structure and. function.. Pace HC, Brenner C;. Genome Biol 2001;2:REVIEWS0001. (from Pfam)
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