Protein Family Models

This HMM hits a C-terminal region, thought to be the anticodin-binding domain, of tRNA ligases for amino acids His, Gly, Thr, and Pro. Proteins named by this HMM are mostly partials, scoring below cutoffs of more specific models because incomplete sequences generate insufficient scores.

Date:

2024-04-03

This HMM finds multiple types of aminoacyl--tRNA ligase, such as those for Thr, Pro, His, and Ser in Escherichia coli. Because equivalog-level HMMs exist to identify full-length members of the tRNA ligase families, any protein receiving annotation from this HMM is most likely to be either a partial sequence or a tRNA ligase-related protein involved in some process other than protein translation on the ribosome.

Date:

2024-04-03

glycine--tRNA ligase catalyzes the attachment of glycine to tRNA(Gly)

Date:

2022-08-10

Catalyzes a two-step reaction, first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

Date:

2021-07-28

This HMM describes a glycyl-tRNA synthetase distinct from the two alpha and two beta chains of the tetrameric E. coli glycyl-tRNA synthetase. This enzyme is a homodimeric class II tRNA synthetase and is recognized by pfam HMM tRNA-synt_2b, which recognizes His, Ser, Pro, and this set of glycyl-tRNA synthetases.

Gene:

glyS

Date:

2023-12-19