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Slit proteins bind Robo receptors and have an evolutionarily conserved role in repulsive axon guidance.
Cell. 1999 Mar 19;96(6):795-806. doi: 10.1016/s0092-8674(00)80590-5.
Cell. 1999.
PMID: 10102268
Free article.
Extracellular Ig domains 1 and 2 of Robo are important for ligand (Slit) binding.
Liu Z, Patel K, Schmidt H, Andrews W, Pini A, Sundaresan V.
Liu Z, et al.
Mol Cell Neurosci. 2004 Jun;26(2):232-40. doi: 10.1016/j.mcn.2004.01.002.
Mol Cell Neurosci. 2004.
PMID: 15207848
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Structural insights into the Slit-Robo complex.
Morlot C, Thielens NM, Ravelli RB, Hemrika W, Romijn RA, Gros P, Cusack S, McCarthy AA.
Morlot C, et al.
Proc Natl Acad Sci U S A. 2007 Sep 18;104(38):14923-8. doi: 10.1073/pnas.0705310104. Epub 2007 Sep 11.
Proc Natl Acad Sci U S A. 2007.
PMID: 17848514
Free PMC article.
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