Complete sequence of enzootic nasal tumor virus, a retrovirus associated with transmissible intranasal tumors of sheep

J Virol. 1999 May;73(5):3986-93. doi: 10.1128/JVI.73.5.3986-3993.1999.

Abstract

The sequence of the complete genome of ovine enzootic nasal tumor virus, an exogenous retrovirus associated exclusively with contagious intranasal tumors of sheep, was determined. The genome is 7,434 nucleotides long and exhibits a genetic organization characteristic of type B and D oncoviruses. Enzootic nasal tumor virus is closely related to the Jaagsiekte sheep retrovirus and to sheep endogenous retroviruses.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acid Sequence
  • Animals
  • Base Sequence
  • Betaretrovirus / classification
  • Betaretrovirus / genetics*
  • DNA, Viral
  • Gene Products, gag / genetics
  • Genes, env
  • Genes, pol
  • Molecular Sequence Data
  • Nose Neoplasms / veterinary*
  • Nose Neoplasms / virology
  • Pulmonary Adenomatosis, Ovine / virology
  • RNA, Spliced Leader
  • Retroviridae Infections / veterinary*
  • Retroviridae Infections / virology
  • Retroviridae Proteins / genetics
  • Sheep
  • Sheep Diseases / virology*
  • Terminal Repeat Sequences
  • Tumor Virus Infections / veterinary*
  • Tumor Virus Infections / virology

Substances

  • DNA, Viral
  • Gene Products, gag
  • RNA, Spliced Leader
  • Retroviridae Proteins

Associated data

  • GENBANK/Y16627