Deficiency in superoxide dismutases shortens life span of yeast cells

J Wawryn; A Krzepiłko; A Myszka; T Biliński

Deficiency in superoxide dismutases shortens life span of yeast cells

Acta Biochim Pol. 1999;46(2):249-53.

Authors

J Wawryn¹, A Krzepiłko, A Myszka, T Biliński

Affiliation

¹ Zamość College of Agriculture, Poland.

PMID: 10547026

Abstract

Deficiencies in superoxide dismutases (Cu,ZnSOD or Mn-SOD) strongly shorten the life span of yeast cells. The effects of these deficiencies are additive. In contrast, deficiencies in catalases do not influence life span. Our results confirm that free radical processes may be involved in aging.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Saccharomyces cerevisiae / cytology*
Saccharomyces cerevisiae / enzymology*
Superoxide Dismutase / metabolism*

Substances

Superoxide Dismutase