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Multiple functional defects in peripheral autonomic organs in mice lacking muscarinic acetylcholine receptor gene for the M3 subtype.
Proc Natl Acad Sci U S A. 2000 Aug 15;97(17):9579-84. doi: 10.1073/pnas.97.17.9579.
Proc Natl Acad Sci U S A. 2000.
PMID: 10944224
Free PMC article.
Mice lacking the M3 muscarinic acetylcholine receptor are hypophagic and lean.
Yamada M, Miyakawa T, Duttaroy A, Yamanaka A, Moriguchi T, Makita R, Ogawa M, Chou CJ, Xia B, Crawley JN, Felder CC, Deng CX, Wess J.
Yamada M, et al.
Nature. 2001 Mar 8;410(6825):207-12. doi: 10.1038/35065604.
Nature. 2001.
PMID: 11242080
Item in Clipboard
A critical role for beta cell M3 muscarinic acetylcholine receptors in regulating insulin release and blood glucose homeostasis in vivo.
Gautam D, Han SJ, Hamdan FF, Jeon J, Li B, Li JH, Cui Y, Mears D, Lu H, Deng C, Heard T, Wess J.
Gautam D, et al.
Cell Metab. 2006 Jun;3(6):449-61. doi: 10.1016/j.cmet.2006.04.009.
Cell Metab. 2006.
PMID: 16753580
Free article.
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Hepatic muscarinic acetylcholine receptors are not critically involved in maintaining glucose homeostasis in mice.
Li JH, Gautam D, Han SJ, Guettier JM, Cui Y, Lu H, Deng C, O'Hare J, Jou W, Gavrilova O, Buettner C, Wess J.
Li JH, et al.
Diabetes. 2009 Dec;58(12):2776-87. doi: 10.2337/db09-0522. Epub 2009 Sep 14.
Diabetes. 2009.
PMID: 19752163
Free PMC article.
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The M3-muscarinic receptor regulates learning and memory in a receptor phosphorylation/arrestin-dependent manner.
Poulin B, Butcher A, McWilliams P, Bourgognon JM, Pawlak R, Kong KC, Bottrill A, Mistry S, Wess J, Rosethorne EM, Charlton SJ, Tobin AB.
Poulin B, et al.
Proc Natl Acad Sci U S A. 2010 May 18;107(20):9440-5. doi: 10.1073/pnas.0914801107. Epub 2010 May 3.
Proc Natl Acad Sci U S A. 2010.
PMID: 20439723
Free PMC article.
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