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The N-terminal region of cystatin A (stefin A) binds to papain subsequent to the two hairpin loops of the inhibitor. Demonstration of two-step binding by rapid-kinetic studies of cystatin A labeled at the N-terminus with a fluorescent reporter group.
Protein Sci. 2000 Nov;9(11):2218-24. doi: 10.1110/ps.9.11.2218.
Protein Sci. 2000.
PMID: 11152132
Free PMC article.
Interactome Mapping Provides a Network of Neurodegenerative Disease Proteins and Uncovers Widespread Protein Aggregation in Affected Brains.
Haenig C, Atias N, Taylor AK, Mazza A, Schaefer MH, Russ J, Riechers SP, Jain S, Coughlin M, Fontaine JF, Freibaum BD, Brusendorf L, Zenkner M, Porras P, Stroedicke M, Schnoegl S, Arnsburg K, Boeddrich A, Pigazzini L, Heutink P, Taylor JP, Kirstein J, Andrade-Navarro MA, Sharan R, Wanker EE.
Haenig C, et al.
Cell Rep. 2020 Aug 18;32(7):108050. doi: 10.1016/j.celrep.2020.108050.
Cell Rep. 2020.
PMID: 32814053
Free article.
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