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The combined functions of proapoptotic Bcl-2 family members bak and bax are essential for normal development of multiple tissues.
Mol Cell. 2000 Dec;6(6):1389-99. doi: 10.1016/s1097-2765(00)00136-2.
Mol Cell. 2000.
PMID: 11163212
Free PMC article.
Combined loss of proapoptotic genes Bak or Bax with Bim synergizes to cause defects in hematopoiesis and in thymocyte apoptosis.
Hutcheson J, Scatizzi JC, Bickel E, Brown NJ, Bouillet P, Strasser A, Perlman H.
Hutcheson J, et al.
J Exp Med. 2005 Jun 20;201(12):1949-60. doi: 10.1084/jem.20041484.
J Exp Med. 2005.
PMID: 15967824
Free PMC article.
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