Cadherins as modulators of angiogenesis and the structural integrity of blood vessels

Cancer Metastasis Rev. 2000;19(1-2):1-5. doi: 10.1023/a:1026522216059.

Abstract

The endothelial cell adhesion molecules, neural- and vascular endothelial-cadherin play essential roles in the formation of stable and fully functional blood vessels. This commentary discusses the multiple functions of these two cadherins in angiogenesis and the maintenance of blood vessel structural integrity.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Blood Vessels / anatomy & histology
  • Blood Vessels / physiology*
  • Cadherins / physiology*
  • Cell Adhesion / physiology
  • Endothelium, Vascular / physiology*
  • Homeostasis
  • Humans
  • Neovascularization, Physiologic / physiology*

Substances

  • Cadherins