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Podoplanin associates with CD44 to promote directional cell migration.
Martín-Villar E, Fernández-Muñoz B, Parsons M, Yurrita MM, Megías D, Pérez-Gómez E, Jones GE, Quintanilla M. Martín-Villar E, et al. Mol Biol Cell. 2010 Dec;21(24):4387-99. doi: 10.1091/mbc.E10-06-0489. Epub 2010 Oct 20. Mol Biol Cell. 2010. PMID: 20962267 Free PMC article.
CD44 variant regulates redox status in cancer cells by stabilizing the xCT subunit of system xc(-) and thereby promotes tumor growth.
Ishimoto T, Nagano O, Yae T, Tamada M, Motohara T, Oshima H, Oshima M, Ikeda T, Asaba R, Yagi H, Masuko T, Shimizu T, Ishikawa T, Kai K, Takahashi E, Imamura Y, Baba Y, Ohmura M, Suematsu M, Baba H, Saya H. Ishimoto T, et al. Cancer Cell. 2011 Mar 8;19(3):387-400. doi: 10.1016/j.ccr.2011.01.038. Cancer Cell. 2011. PMID: 21397861 Free article.