Resistance to paromomycin is conferred by rpsL mutations, accompanied by an enhanced antibiotic production in Streptomyces coelicolor A3(2)

J Antibiot (Tokyo). 2000 Dec;53(12):1424-7. doi: 10.7164/antibiotics.53.1424.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Drug Resistance, Microbial / genetics
  • Genes, Bacterial*
  • Mutation*
  • Paromomycin / biosynthesis
  • Paromomycin / pharmacology*
  • Ribosomal Proteins / genetics*
  • Streptomyces / genetics
  • Streptomyces / metabolism*

Substances

  • Ribosomal Proteins
  • ribosomal protein S12
  • Paromomycin