Analysis of major components and bisphenol A in commercial Bis-GMA and Bis-GMA-based resins using high performance liquid chromatography

Dent Mater J. 2000 Sep;19(3):263-9. doi: 10.4012/dmj.19.263.

Abstract

The purpose of this study was to examine the quality of commercially available Bis-GMA because concerns about Bis-GMA and Bis-GMA-based resins have been recently expressed in dentistry. Four major components and bisphenol A, which is a compound of recent controversy, were quantitatively analyzed using high performance liquid chromatography (HPLC) in three commercial Bis-GMA and six Bis-GMA-based composite resins. The contents of genuine Bis-GMA, Iso-bis-GMA, Bis-GMA-H, and Bis-GMA-M as well as the total content of the four monomers were 45.7-57.5%, 19.9-26.2%, 1.8-5.0%, 0.6-15.0% and 83.7-85.6% in the commercial Bis-GMAs, or 3.8-9.1%, 1.7-4.3%, 0.1-0.5%, 0.1-2.0% and 5.8-14.0% in composite resins, respectively. There were some differences in the composition of the major components between domestic and foreign materials. Bisphenol A contents in the unpolymerized composite resins were 1.5-10.2 micrograms/g resin.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Benzhydryl Compounds
  • Bisphenol A-Glycidyl Methacrylate / chemistry*
  • Bisphenol A-Glycidyl Methacrylate / standards*
  • Chromatography, High Pressure Liquid
  • Estrogens, Non-Steroidal / analysis*
  • Phenols / analysis*
  • Resin Cements / chemistry

Substances

  • Benzhydryl Compounds
  • Estrogens, Non-Steroidal
  • Phenols
  • Resin Cements
  • Bisphenol A-Glycidyl Methacrylate
  • bisphenol A