Abstract
Gene expression is finely regulated at the post-transcriptional level. Features of the untranslated regions of mRNAs that control their translation, degradation and localization include stem-loop structures, upstream initiation codons and open reading frames, internal ribosome entry sites and various cis-acting elements that are bound by RNA-binding proteins.
Publication types
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Research Support, Non-U.S. Gov't
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Review
MeSH terms
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Animals
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Codon, Initiator / genetics
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Humans
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Nucleic Acid Conformation
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Protein Biosynthesis / genetics
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RNA Processing, Post-Transcriptional / genetics
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RNA Stability / genetics
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RNA, Messenger / chemistry*
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RNA, Messenger / genetics*
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RNA, Messenger / metabolism
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Untranslated Regions / chemistry*
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Untranslated Regions / genetics*
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Untranslated Regions / metabolism
Substances
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Codon, Initiator
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RNA, Messenger
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Untranslated Regions