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SB-431542 is a potent and specific inhibitor of transforming growth factor-beta superfamily type I activin receptor-like kinase (ALK) receptors ALK4, ALK5, and ALK7.
Mol Pharmacol. 2002 Jul;62(1):65-74. doi: 10.1124/mol.62.1.65.
Mol Pharmacol. 2002.
PMID: 12065756
Ttrap is an essential modulator of Smad3-dependent Nodal signaling during zebrafish gastrulation and left-right axis determination.
Esguerra CV, Nelles L, Vermeire L, Ibrahimi A, Crawford AD, Derua R, Janssens E, Waelkens E, Carmeliet P, Collen D, Huylebroeck D.
Esguerra CV, et al.
Development. 2007 Dec;134(24):4381-93. doi: 10.1242/dev.000026.
Development. 2007.
PMID: 18039968
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